Your search for returned 6,401 results
Research
Fetal signatures in the 3D genome of iPSC-derived neurons and their implications for disease modeling
- First Published August 3, 2026
Research
Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments
- First Published July 30, 2026
Method
Knowledge-driven interpretable neural networks for mechanistic insight
- First Published July 24, 2026
Method
Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks
- First Published July 22, 2026
Method
Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI
- First Published July 22, 2026
Research
Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer
- First Published July 17, 2026
Research
Methylation variability and LINE-1 transcriptional activation in multiple myeloma
- First Published July 17, 2026
Method
ComicGTN infers disease-associated rare cell states from single-cell multiomic data using DNA sequence–augmented graph transformer networks
- First Published July 17, 2026
Research
Genome-wide crossover analysis in the holocentric pantry moth reveals strong crossover assurance and interference during spermatogenesis
- First Published July 16, 2026
Research
The impact of sex, age, and genetic ancestry on DNA methylation across tissues
- First Published July 14, 2026
Method
A sequence-based classifier distinguishes phenotype-associated genes from other gene models in plants
- First Published July 14, 2026
Research
An RNA polymerase III tissue and tumor atlas uncovers context-specific activities linked to 3D epigenome regulatory mechanisms
- First Published July 13, 2026
Method
Biobank-scale genotype similarity search and dynamic patient-matched cohort creation with GenoSiS
- First Published July 10, 2026
Method
De novo structural variants in autism spectrum disorder disrupt distal regulatory interactions of neuronal genes
- First Published July 8, 2026
Resource
Dietary effects on cytosolic and mitochondrial tRNA abundance and modification patterns across mouse tissues
- First Published July 8, 2026
Research
Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma
- First Published July 8, 2026
Corrigendum
Corrigendum: Evaluation of strategies for evidence-driven genome annotation using long-read RNA-seq
- First Published July 7, 2026
Corrigendum
Corrigendum: Characterizing cytosine methylation of polymorphic transposable element insertions using the human pangenome resources
- First Published July 7, 2026
Corrigendum
Corrigendum: Systematic evaluation of the effect of polyadenylation signal variants on the expression of disease-associated genes
- First Published July 7, 2026
Method
High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV
- First Published July 6, 2026
Resource
Complete sequencing of medaka genomes reveals the architecture of centromeric satellites, giant mobile elements, and sex chromosomes
- First Published July 1, 2026
Research
Convergence and conflict among telomere specialized transposons across 60 million years of Drosophilid evolution
- First Published July 1, 2026
Research
Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture
- First Published June 29, 2026
Method
A unified analysis of cell-type- and trajectory-associated pathways in single-cell data using Phoenix
- First Published June 29, 2026
Method
Locations of consecutive G•C base pairs direct genomic nucleosome positioning
- First Published June 25, 2026
Method
Spatially informed reference-free cell-type deconvolution for spatial transcriptomics with SpatialCD
- First Published June 22, 2026
Research
Spatially resolved profiling of steroid nuclear receptors reveals a role for the disordered N-terminal domains in genome targeting and AP-1 interaction
- First Published June 22, 2026
Perspective
The Topological Regulatory Logic of noncoding RNA–mediated gene expression
- First Published June 17, 2026
Method
Flexible and scalable inference of spatially varying correlation in spatial transcriptomics with spCorr
- First Published June 17, 2026
Resource
Tracing genome size dynamics in sharks and rays with inclusive sequence analysis by the Squalomix Consortium
- First Published June 16, 2026
Research
Covariation of genetic and epigenetic divergence in barn swallows
- First Published June 16, 2026
Method
MAPLE enables ultrasensitive detection of low-frequency cfDNA methylation haplotypes using short capture probes with cost-efficient performance
- First Published June 16, 2026
Research
Cyanophora paradoxa reveals unique repair signature" > Elevated DNA insertion rate in Cyanophora paradoxa reveals unique repair signature
- First Published June 12, 2026
Method
A comparison of ancient DNA yields across ossicles and the petrous bone reveals the best preservation in the stapes and incus
- First Published June 11, 2026
Research
Evolution of an adaptive, inducible defensive trait in a model crustacean
- First Published June 5, 2026
Method
Reference-informed spatial domain detection using weak supervision for spatial transcriptomics
- First Published June 3, 2026
Method
Transfer learning enhances clinical utility of polygenic scores with small, phenotypically refined cohorts
- First Published June 2, 2026
Research
Genome evolution in parthenogenetic nematodes shaped by chromosome rearrangements and introgression
- First Published May 29, 2026
Method
Augmenting transcriptome annotations through the lens of splicing evolution
- First Published May 29, 2026
Research
Transposable element small RNAs and large RNAs in aging brains and implications in Huntington's and Parkinson's disease
- First Published May 28, 2026
Research
Whole-genome variant detection in long-read sequencing data from ultralow input patient samples
- First Published May 28, 2026
Resource
A comprehensive single-cell atlas of monoallelic expression across various tissues in zebrafish
- First Published May 28, 2026
Method
RECOMBINE identifies recurrent composite markers of cell types and states
- First Published May 20, 2026
Research
Interplay between purging and admixture shapes genetic load in an invasive guppy population
- First Published May 20, 2026
Research
Herbaria provide a valuable resource for obtaining informative mRNA
- First Published May 19, 2026
Review
Building genomic data structures from compressed representations using prefix-free parsing
- First Published May 15, 2026
Method
Cultivation-independent high-quality microbial genome reconstruction from environmental samples with midi-metagenomics
- First Published May 15, 2026
Research
N-ethyl-N-nitrosourea" > Evidence for negative selection against somatic mutations induced in normal fibroblasts by N-ethyl-N-nitrosourea
- First Published May 15, 2026
Method
Accurate delineation of cellular niches via integrated spatial transcriptomics and histological imaging with SYMOL
- First Published May 14, 2026
Research
Allele-specific splicing modulates protein isoforms and Alzheimer's disease risk
- First Published May 14, 2026
Research
Characterizing cytosine methylation of polymorphic transposable element insertions using the human pangenome resources
- First Published May 14, 2026
Research
DNA conformational flexibility descriptors improve transcription factor binding prediction across diverse transcription factor families
- First Published May 14, 2026
Method
Tree reconstruction guarantees from CRISPR-Cas9 lineage tracing data using Neighbor-Joining
- First Published May 14, 2026
Research
Single-cell transcriptomics reveals rapid divergence of genes guiding meiosis and spermiogenesis in two passerine birds
- First Published May 14, 2026
Research
Drosophila" > Structural variants are enriched in deleterious visible phenotypes in Drosophila
- First Published May 14, 2026
Research
Dynamic body size evolution during speciation of predatory cichlid fishes in the Lake Malawi superradiation
- First Published May 4, 2026
Research
Single-cell template strand sequencing reveals culture-induced chromosomal instability in a gibbon cell line
- First Published May 4, 2026
Research
R-loops shape the H2A.Z landscape and promote balanced lineage allocation during differentiation
- First Published May 4, 2026
Method
Using CRISPR barcoding as a molecular clock to capture dynamic processes at single-cell resolution
- First Published May 1, 2026
Method
Genealogy-based trait association with LOCATER boosts power at loci with allelic heterogeneity
- First Published April 16, 2026
Method
Balancing Gene Ontology annotation specificity in protein function prediction based on the protein sequence large graph
- First Published April 15, 2026
Research
Age-dependent mutational loads in human tRNA genes are tumor-specific and result in chimeric tRNA sequences that could disrupt the genetic code
- First Published April 15, 2026
Research
Drosophila innate immune response" > A genome-wide survey reveals that a diverse array of enhancers coordinates the Drosophila innate immune response
- First Published April 15, 2026
Research
Epigenetic characterization of pseudogenes across human tissues
- First Published April 15, 2026
Method
Highly efficient and scarless genome editing via essential-gene-coupled homology-directed repair
- First Published April 15, 2026
Method
Dynamics of intronic polyadenylation in the hematopoietic lineage and its regulation by DNA methylation
- First Published April 13, 2026
Method
Simultaneous modeling of chromatin conformation changes from multiple single-cell interaction maps with ChromMovie
- First Published April 8, 2026
Resource
Lignature provides a curated resource of ligand-induced transcriptomic signatures for signaling inference
- First Published April 8, 2026
Method
Nanopore sequencing identifies high-frequency somatic structural variations in laryngeal squamous cell carcinoma genomes
- First Published April 8, 2026
Method
Enabling efficient and robust analysis of tandem repeats in genomic data using Wavefront-based String Decomposer
- First Published April 8, 2026
Resource
Whole-genome sequencing of diverse 351 cultured prokaryotes including as-yet-unsequenced type strains
- First Published April 7, 2026
Corrigendum
Corrigendum: TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation
- First Published April 7, 2026
Research
Dynamics and consequences of differential RNA isoform production during cardiomyocyte fate determination and early-stage maturation
- First Published April 3, 2026
Method
Incorporating valuable prior knowledge to improve deep learning prediction of genetic perturbation responses
- First Published March 26, 2026
Resource
Isoform- and pathway-specific regulation of post-transcriptional RNA processing in human cells
- First Published March 26, 2026
Method
High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND
- First Published March 26, 2026
Research
Centromeric instability and chromoanasynthesis observed in nine supernumerary marker chromosomes resolved with long-read genome sequencing
- First Published March 25, 2026
Research
ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells
- First Published March 25, 2026
Method
Complete genetic and epigenetic architecture of D4Z4 macrosatellites in FSHD, BAMS, and reference cohorts with D4Z4End2End
- First Published March 23, 2026
Method
k-mer cross-species profiling reveals taxon-specific TE expansions accompanied by KZFP co-option and functional impacts in ruminants" > k-mer cross-species profiling reveals taxon-specific TE expansions accompanied by KZFP co-option and functional impacts in ruminants
- First Published March 23, 2026
Method
High-resolution genotype-free mapping of genetic variation with CRI-SPA-Map
- First Published March 23, 2026
Method
Restoring the potency of a neutralizing antibody via guided hypermutation with hyper-antibody editor HAE1
- First Published March 19, 2026
Method
Parallel analysis of replication timing, gene expression, and copy number with PARTAGE
- First Published March 19, 2026
Research
cis-antisense RNA duplexes" > A transcriptome-wide systematic search does not detect A-to-I RNA editing in cis-antisense RNA duplexes
- First Published March 12, 2026
Method
Scalable cell-specific coexpression networks for granular regulatory pattern discovery with NeighbourNet
- First Published March 5, 2026
Method
Minimizing reference bias with an imputed personalized reference
- First Published March 5, 2026
Method
Automated interpretable artificial intelligence genomic prediction with AIGP
- First Published March 5, 2026
Resource
Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease
- First Published March 4, 2026
Research
Confounding factors in assessing the enriched expression of somatic mutant alleles in bulk tumor samples
- First Published March 4, 2026
Research
Dynamic A-to-I RNA editing in response to gut microbiome in honey bees
- First Published March 4, 2026