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Research

Fetal signatures in the 3D genome of iPSC-derived neurons and their implications for disease modeling

  • First Published August 3, 2026
Research

MEIS1 in conferring sleep abnormalities and impaired cerebellar development" > Cross-species variant-to-function analyses implicate MEIS1 in conferring sleep abnormalities and impaired cerebellar development

  • First Published July 30, 2026
Research

Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments

  • First Published July 30, 2026
Research

Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer

  • First Published July 17, 2026
Research

Methylation variability and LINE-1 transcriptional activation in multiple myeloma

  • First Published July 17, 2026
Research

Genome-wide crossover analysis in the holocentric pantry moth reveals strong crossover assurance and interference during spermatogenesis

  • First Published July 16, 2026
Research

The impact of sex, age, and genetic ancestry on DNA methylation across tissues

  • First Published July 14, 2026
Research

An RNA polymerase III tissue and tumor atlas uncovers context-specific activities linked to 3D epigenome regulatory mechanisms

  • First Published July 13, 2026
Research

Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma

  • First Published July 8, 2026
Research

Convergence and conflict among telomere-specialized transposons across 60 million years of Drosophilid evolution

  • First Published July 1, 2026
Research

Resf1 is required for proper placental development and configuration of trophoblast cell–specific heterochromatin" > Resf1 is required for proper placental development and configuration of trophoblast cell–specific heterochromatin

  • First Published June 29, 2026
Research

Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture

  • First Published June 29, 2026
Research

Spatially resolved profiling of steroid nuclear receptors reveals a role for the disordered N-terminal domains in genome targeting and AP-1 interaction

  • First Published June 22, 2026
Research

Covariation of genetic and epigenetic divergence in barn swallows

  • First Published June 16, 2026
Research

Cyanophora paradoxa reveals unique repair signature" > Elevated DNA insertion rate in Cyanophora paradoxa reveals unique repair signature

  • First Published June 12, 2026
Research

Evolution of an adaptive, inducible defensive trait in a model crustacean

  • First Published June 5, 2026
Research

Genome evolution in parthenogenetic nematodes shaped by chromosome rearrangements and introgression

  • First Published May 29, 2026
Research

Transposable element small RNAs and large RNAs in aging brains and implications in Huntington's and Parkinson's disease

  • First Published May 28, 2026
Research

Whole-genome variant detection in long-read sequencing data from ultralow input patient samples

  • First Published May 28, 2026
Research

Interplay between purging and admixture shapes genetic load in an invasive guppy population

  • First Published May 20, 2026
Research

Herbaria provide a valuable resource for obtaining informative mRNA

  • First Published May 19, 2026
Research

N-ethyl-N-nitrosourea" > Evidence for negative selection against somatic mutations induced in normal fibroblasts by N-ethyl-N-nitrosourea

  • First Published May 15, 2026
Research

Allele-specific splicing modulates protein isoforms and Alzheimer's disease risk

  • First Published May 14, 2026
Research

Characterizing cytosine methylation of polymorphic transposable element insertions using the human pangenome resources

  • First Published May 14, 2026
Research

Single-cell transcriptomics reveals rapid divergence of genes guiding meiosis and spermiogenesis in two passerine birds

  • First Published May 14, 2026
Research

Drosophila" > Structural variants are enriched in deleterious visible phenotypes in Drosophila

  • First Published May 14, 2026
Research

6A reprogramming unveils vitamin-driven post-transcriptional regulation in mice" > Tissue-specific mRNA m6A reprogramming unveils vitamin-driven post-transcriptional regulation in mice

  • First Published May 11, 2026
Research

Dynamic body size evolution during speciation of predatory cichlid fishes in the Lake Malawi superradiation

  • First Published May 4, 2026
Research

Single-cell template strand sequencing reveals culture-induced chromosomal instability in a gibbon cell line

  • First Published May 4, 2026
Research

R-loops shape the H2A.Z landscape and promote balanced lineage allocation during differentiation

  • First Published May 4, 2026
Research

Age-dependent mutational loads in human tRNA genes are tumor-specific and result in chimeric tRNA sequences that could disrupt the genetic code

  • First Published April 15, 2026
Research

Drosophila innate immune response" > A genome-wide survey reveals that a diverse array of enhancers coordinates the Drosophila innate immune response

  • First Published April 15, 2026
Research

Epigenetic characterization of pseudogenes across human tissues

  • First Published April 15, 2026
Research

Dynamics and consequences of differential RNA isoform production during cardiomyocyte fate determination and early-stage maturation

  • First Published April 3, 2026
Research

Centromeric instability and chromoanasynthesis observed in nine supernumerary marker chromosomes resolved with long-read genome sequencing

  • First Published March 25, 2026
Research

ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells

  • First Published March 25, 2026
Research

Aphelenchus avenae implicates P5CS in nematode desiccation stress response" > Haplotype-resolved telomere-to-telomere genome of Aphelenchus avenae implicates P5CS in nematode desiccation stress response

  • First Published March 23, 2026
Research

cis-antisense RNA duplexes" > A transcriptome-wide systematic search does not detect A-to-I RNA editing in cis-antisense RNA duplexes

  • First Published March 12, 2026
Research

Confounding factors in assessing the enriched expression of somatic mutant alleles in bulk tumor samples

  • First Published March 4, 2026
Research

cis-regulatory modules acting during vertebrate organogenesis" > Functional genomics analysis of developing zebrafish and human endoderm reveals highly conserved cis-regulatory modules acting during vertebrate organogenesis

  • First Published March 4, 2026
Research

Dynamic A-to-I RNA editing in response to gut microbiome in honey bees

  • First Published March 4, 2026
Research

Assessing the readiness of Oxford Nanopore sequencing for clinical genomics applications

  • First Published February 11, 2026
Research

Drosophila species" > Transposable elements contribute to the evolution of host shift–related genes in cactophilic Drosophila species

  • First Published February 10, 2026
Research

Degrees of convergent evolution in rodent adaptations to arid environments

  • First Published January 21, 2026
Research

Saccharomyces cerevisiae strains" > Natural diversity of telomere length distributions across 100 Saccharomyces cerevisiae strains

  • First Published January 16, 2026
Research

Stable genome structures in living fossil fishes

  • First Published January 13, 2026
Research

MHC in newts illuminates the evolutionary dynamics of complex regions in giant genomes

  • First Published January 12, 2026
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