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Chromosome-scale genome assembly and annotation of Octodon degus

  • First Published October 26, 2026
Method

Integration-free and cluster-free detection of localized differential gene coexpression in single-cell data with DiCoLo

  • First Published October 26, 2026
Method

A new noninvasive prenatal paternity test based on double nucleotide polymorphisms abates sequencing uncertainties and improves sensitivity

  • First Published October 23, 2026
Resource

Developmental transcriptomic analysis of primary mouse cortical neurons reveals sex-specific expression of neuropeptides

  • First Published October 23, 2026
Method

Refining indel- and structural variant-trait associations with LAVrefiner

  • First Published October 21, 2026
Research

Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs in three ray-finned fishes

  • First Published October 21, 2026
Method

The Vizitig pangenome and pantranscriptome explorer

  • First Published October 21, 2026
Research

Base composition reflects RNA polymerase II displacement

  • First Published October 21, 2026
Research

Liver X receptors participate in the fasting response by assisting CEBPB binding to enhancers and promoting the fasting transcriptional program

  • First Published October 16, 2026
Resource

Glucocorticoid regulation of the human noncoding genome

  • First Published October 16, 2026
Method

Conditional diffusion for single-cell Hi-C data imputation and enhancement with scHiC-Diff

  • First Published October 16, 2026
Research

Pangenome and transcriptomics reveal the genomic basis associated with interspecific variation of sexually dimorphic nuptial spines in moustache toads

  • First Published October 16, 2026
Research

The divergent 3D genome landscapes of aging and neurodegenerative mouse models

  • First Published October 13, 2026
Research

Identity-by-descent captures shared environmental factors at biobank scale

  • First Published October 13, 2026
Research

Parental genome reprogramming drives allelic convergence while preserving parent-of-origin memory during human early embryonic development

  • First Published October 13, 2026
Method

Reconstruction of contact signals from repeated elements with Hicberg

  • First Published October 13, 2026
Method

Single-cell transcriptome analysis reveals onco-fetal reprogramming with implications for drug resistance and clinical outcome

  • First Published October 9, 2026
Method

Protein large language model–assisted one-to-one gene homology mapping in cross-species single-cell transcriptome integration

  • First Published October 9, 2026
Research

Temporal transcriptomics identifies trans-regulation by multiple lncRNAs in human iPSCs

  • First Published October 9, 2026
Research

Error correction algorithms for efficient gene expression quantification in single cell transcriptomics with Arcane

  • First Published October 7, 2026
Research

Shared transcriptional consequences of epigenetic machinery disruption in murine neuronal progenitors

  • First Published October 7, 2026
Method

Optical genome mapping identifies clinically relevant somatic structural variation in epilepsy-affected brain tissue

  • First Published October 1, 2026
Research

Meso-scale spatial analysis of papilloma formation and clonal expansion in cancerized skin

  • First Published October 1, 2026
Method

Scaling coalescent-based species tree inference to 100,000 taxa with STELAR-X

  • First Published October 1, 2026
Method

Fast and accurate construction of multiple sequence alignments from protein language embeddings with ARIES

  • First Published October 1, 2026
Corrigendum

Corrigendum: Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing

  • First Published October 1, 2026
Research

Dissecting functional regulatory convergence over 160 million years of therian evolution

  • First Published September 23, 2026
Method

Viral haplotype reconstruction from long reads with virCHap

  • First Published September 23, 2026
Method

Multilevel ensemble for genome-wide prediction of cell-specific G-quadruplexes utilizing transformed sequences and enhanced chromatin accessibility with G4Beacon2

  • First Published September 22, 2026
Method

Deep genomic models of allele-specific measurements

  • First Published September 21, 2026
Method

Decoding cell division history and lineage-resolved phenotypic patterns from single-cell barcode and transcriptomic data

  • First Published September 21, 2026
Research

Spatial genome organization in nematodes with programmed DNA elimination

  • First Published September 21, 2026
Method

CircExor enables interpretable prediction of circRNA localization into extracellular vesicles

  • First Published September 17, 2026
Method

Unifying multimodal single-cell data with a mixture-of-experts β-variational autoencoder framework

  • First Published September 16, 2026
Method

Dual-contrastive learning for spatial domain identification in spatial transcriptomics with STAMGC

  • First Published September 16, 2026
Resource

SwinePan for pig graph-based pangenome and multiomics data mining

  • First Published September 16, 2026
Research

Combined effects of Ret coding and enhancer loss-of-function alleles cause progressive loss of inhibitory motor neurons in the enteric nervous system

  • First Published September 16, 2026
Method

k-mer-based Upstream Preprocessing of long reads for Isoform Discovery

  • First Published September 14, 2026
Resource

T2T genomes of Caenorhabditis nigoni and Caenorhabditis briggsae reveal divergence in satellite DNA abundance

  • First Published September 4, 2026
Method

Resolving missing human polymorphic inversions and other complex variants from ultralong read data

  • First Published September 1, 2026
Method

Identification of differential topologically associating domains from low sequencing depth and pseudobulk chromatin contact maps

  • First Published August 28, 2026
Method

Robust annotation and discovery of novel cell types in single-cell ATAC-seq data through cross-modal reference alignment

  • First Published August 28, 2026
Method

Achieving spatial multiomics diagonal integration from unaligned serial sections with DIME

  • First Published August 26, 2026
Research

A network of steroid receptor transcription factors regulates ovarian chromatin remodeling in the transition to ovulation

  • First Published August 25, 2026
Method

Bayesian inference of lineage trees by joint analysis of single-cell multimodal lineage-tracing data with BiLinT

  • First Published August 21, 2026
Method

A biobank-scale method for learning modulators of gene-environment interaction underlying human complex traits from multiple environmental exposures

  • First Published August 18, 2026
Research

Nuclear mitochondrial sequences in great ape telomere-to-telomere genomes

  • First Published August 18, 2026
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