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Research

Aphelenchus avenae implicates P5CS in nematode desiccation stress response" > Haplotype-resolved telomere-to-telomere genome of Aphelenchus avenae implicates P5CS in nematode desiccation stress response

  • First Published March 23, 2026
Method

High-resolution genotype-free mapping of genetic variation with CRI-SPA-Map

  • First Published March 23, 2026
Method

Restoring the potency of a neutralizing antibody via guided hypermutation with hyper-antibody editor HAE1

  • First Published March 19, 2026
Method

Parallel analysis of replication timing, gene expression, and copy number with PARTAGE

  • First Published March 19, 2026
Research

cis-antisense RNA duplexes" > A transcriptome-wide systematic search does not detect A-to-I RNA editing in cis-antisense RNA duplexes

  • First Published March 12, 2026
Method

Scalable cell-specific coexpression networks for granular regulatory pattern discovery with NeighbourNet

  • First Published March 5, 2026
Method

Minimizing reference bias with an imputed personalized reference

  • First Published March 5, 2026
Method

Automated interpretable artificial intelligence genomic prediction with AIGP

  • First Published March 5, 2026
Resource

Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease

  • First Published March 4, 2026
Research

Confounding factors in assessing the enriched expression of somatic mutant alleles in bulk tumor samples

  • First Published March 4, 2026
Research

cis-regulatory modules acting during vertebrate organogenesis" > Functional genomics analysis of developing zebrafish and human endoderm reveals highly conserved cis-regulatory modules acting during vertebrate organogenesis

  • First Published March 4, 2026
Research

Dynamic A-to-I RNA editing in response to gut microbiome in honey bees

  • First Published March 4, 2026
Erratum

Erratum: Expanded methylome and quantitative trait loci detection by long-read profiling of personal DNA

  • First Published March 2, 2026
Method

Gene duplication is associated with gene diversification and potential neofunctionalization in lung cancer evolution

  • First Published February 19, 2026
Method

Robust and efficient annotation of cell states through gene signature scoring

  • First Published February 18, 2026
Review

A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest

  • First Published February 17, 2026
Method

Mapping and quantifying nascent transcript start sites using TT-TSS-seq

  • First Published February 17, 2026
Research

Assessing the readiness of Oxford Nanopore sequencing for clinical genomics applications

  • First Published February 11, 2026
Research

Drosophila species" > Transposable elements contribute to the evolution of host shift–related genes in cactophilic Drosophila species

  • First Published February 10, 2026
Method

Analysis of coding gene expression from small RNA sequencing

  • First Published February 10, 2026
Method

spRefine denoises and imputes spatial transcriptomic data with a reference-free framework powered by genomic language model

  • First Published February 3, 2026
Corrigendum

Corrigendum: Machine learning identifies activation of RUNX/AP-1 as drivers of mesenchymal and fibrotic regulatory programs in gastric cancer

  • First Published February 3, 2026
Resource

Tetrahymena" > A systems view on DNA damage response kinetics in Tetrahymena

  • First Published January 28, 2026
Research

Degrees of convergent evolution in rodent adaptations to arid environments

  • First Published January 21, 2026
Resource

Cell type–specific gene regulatory atlas prioritizes drug targets and repurposable medicines in Alzheimer's disease

  • First Published January 21, 2026
Method

scSHEFT enables multiomics label transfer from scRNA-seq to scATAC-seq through dual alignment

  • First Published January 20, 2026
Method

Autoencoders for genomic variation analysis

  • First Published January 20, 2026
Review

Recent advances in methods to characterize archaic introgression in modern humans

  • First Published January 16, 2026
Method

cis-regulatory elements" > A scalable computational framework for predicting gene expression from candidate cis-regulatory elements

  • First Published January 16, 2026
Research

Saccharomyces cerevisiae strains" > Natural diversity of telomere length distributions across 100 Saccharomyces cerevisiae strains

  • First Published January 16, 2026
Method

Read-level genotyping of short tandem repeats using long reads and single-nucleotide variation with STRkit

  • First Published January 15, 2026
Method

Quantifying pathological progression from single-cell transcriptomic data with scPSS

  • First Published January 14, 2026
Method

Strain-level metagenomic profiling using pangenome graphs with PanTax

  • First Published January 14, 2026
Research

Stable genome structures in living fossil fishes

  • First Published January 13, 2026
Research

Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells

  • First Published January 12, 2026
Research

MHC in newts illuminates the evolutionary dynamics of complex regions in giant genomes

  • First Published January 12, 2026
Method

Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation

  • First Published January 12, 2026
Method

Early feature extraction drives model performance in high-resolution chromatin accessibility prediction

  • First Published January 12, 2026
Research

LTR7-PLAAT4 as a potential oncogene and therapeutic target in pancreatic adenocarcinoma" > Transcriptomic landscape of transposable elements reveals LTR7-PLAAT4 as a potential oncogene and therapeutic target in pancreatic adenocarcinoma

  • First Published January 8, 2026
Method

A spectral component approach leveraging identity-by-descent graphs to address recent population structure in genomic analysis

  • First Published December 23, 2025
Resource

The SynMall resource for characterizing the functional impact of synonymous variation

  • First Published December 17, 2025
Method

Automated chromatin profiling with spa-ChIP-seq uncovers the impacts of condition variations

  • First Published December 12, 2025
Research

XIST isoform in male peripheral glia" > Transcription and potential functions of a novel XIST isoform in male peripheral glia

  • First Published December 12, 2025
Resource

The PanOryza pangene catalog of Asian cultivated rice

  • First Published December 12, 2025
Method

The oligogenic inheritance test GCOD detects risk genes and their interactions in congenital heart defects

  • First Published December 12, 2025
Method

6A demethylation in mRNAs" > A versatile type VI CRISPR-based approach for targeted m6A demethylation in mRNAs

  • First Published December 11, 2025
Research

Drosophila testis tumor stem cell–like cells" > Cell-type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem cell–like cells

  • First Published December 10, 2025
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