Method
Dual-contrastive learning for spatial domain identification in spatial transcriptomics with STAMGC
- First Published September 16, 2026
Method
Unifying multimodal single-cell data with a mixture-of-experts β-variational autoencoder framework
- First Published September 16, 2026
Method
k-mer-based Upstream Preprocessing of long reads for Isoform Discovery" > k-mer-based Upstream Preprocessing of long reads for Isoform Discovery
- First Published September 14, 2026
Method
Resolving missing human polymorphic inversions and other complex variants from ultra-long read data
- First Published September 1, 2026
Method
Identification of differential topologically associating domains from low sequencing depth and pseudo-bulk chromatin contact maps
- First Published August 28, 2026
Method
Robust annotation and discovery of novel cell types in single-cell ATAC-seq data through cross-modal reference alignment
- First Published August 28, 2026
Method
Achieving spatial multiomics diagonal integration from unaligned serial sections with DIME
- First Published August 26, 2026
Method
Accurate reconstruction of spatial cell type maps and characterization of domain-specific functions based on a gene-aware heterogeneous network
- First Published August 25, 2026
Method
Bayesian inference of lineage trees by joint analysis of single-cell multimodal lineage-tracing data with BiLinT
- First Published August 21, 2026
Method
A biobank-scale method for learning modulators of gene-environment interaction underlying human complex traits from multiple environmental exposures
- First Published August 18, 2026
Method
Detecting somatic mutations in rare clones using single-cell multiomics
- First Published August 13, 2026
Method
A SNP panel for coanalysis of capture and shotgun ancient DNA data
- First Published August 12, 2026
Method
Pattern-Filter structural validation of single-cell RNA-seq reads reduces artifactual barcodes and improves biological resolution
- First Published August 12, 2026
Method
Knowledge-driven interpretable neural networks provide mechanistic insight
- First Published July 24, 2026
Method
Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks
- First Published July 22, 2026
Method
Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI
- First Published July 22, 2026
Method
ComicGTN infers disease-associated rare cell states from single-cell multiomic data using DNA sequence–augmented graph transformer networks
- First Published July 17, 2026
Method
A sequence-based classifier distinguishes phenotype-associated genes from other gene models in plants
- First Published July 14, 2026
Method
Biobank-scale genotype similarity search and dynamic patient-matched cohort creation with GenoSiS
- First Published July 10, 2026
Method
De novo structural variants in autism spectrum disorder disrupt distal regulatory interactions of neuronal genes
- First Published July 8, 2026
Method
High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV
- First Published July 6, 2026
Method
A unified analysis of cell-type- and trajectory-associated pathways in single-cell data using Phoenix
- First Published June 29, 2026
Method
Locations of consecutive G•C base pairs direct genomic nucleosome positioning
- First Published June 25, 2026
Method
Spatially informed reference-free cell-type deconvolution for spatial transcriptomics with SpatialCD
- First Published June 22, 2026
Method
Flexible and scalable inference of spatially varying correlation in spatial transcriptomics with spCorr
- First Published June 17, 2026
Method
MAPLE enables ultrasensitive detection of low-frequency cfDNA methylation haplotypes using short capture probes with cost-efficient performance
- First Published June 16, 2026
Method
A comparison of ancient DNA yields across ossicles and the petrous bone reveals the best preservation in the stapes and incus
- First Published June 11, 2026
Method
Reference-informed spatial domain detection using weak supervision for spatial transcriptomics
- First Published June 3, 2026
Method
Transfer learning enhances clinical utility of polygenic scores with small, phenotypically refined cohorts
- First Published June 2, 2026
Method
Augmenting transcriptome annotations through the lens of splicing evolution
- First Published May 29, 2026
Method
RECOMBINE identifies recurrent composite markers of cell types and states
- First Published May 20, 2026
Method
Cultivation-independent high-quality microbial genome reconstruction from environmental samples with midi-metagenomics
- First Published May 15, 2026
Method
Tree reconstruction guarantees from CRISPR-Cas9 lineage tracing data using Neighbor-Joining
- First Published May 14, 2026
Method
Accurate delineation of cellular niches via integrated spatial transcriptomics and histological imaging with SYMOL
- First Published May 14, 2026
Method
Using CRISPR barcoding as a molecular clock to capture dynamic processes at single-cell resolution
- First Published May 1, 2026
Method
Genealogy-based trait association with LOCATER boosts power at loci with allelic heterogeneity
- First Published April 16, 2026
Method
Balancing Gene Ontology annotation specificity in protein function prediction based on the protein sequence large graph
- First Published April 15, 2026
Method
Highly efficient and scarless genome editing via essential-gene-coupled homology-directed repair
- First Published April 15, 2026
Method
Dynamics of intronic polyadenylation in the hematopoietic lineage and its regulation by DNA methylation
- First Published April 13, 2026
Method
Simultaneous modeling of chromatin conformation changes from multiple single-cell interaction maps with ChromMovie
- First Published April 8, 2026
Method
Enabling efficient and robust analysis of tandem repeats in genomic data using Wavefront-based String Decomposer
- First Published April 8, 2026
Method
Nanopore sequencing identifies high-frequency somatic structural variations in laryngeal squamous cell carcinoma genomes
- First Published April 8, 2026
Method
Incorporating valuable prior knowledge to improve deep learning prediction of genetic perturbation responses
- First Published March 26, 2026
Method
High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND
- First Published March 26, 2026
Method
k-mer cross-species profiling reveals taxon-specific TE expansions accompanied by KZFP co-option and functional impacts in ruminants" > k-mer cross-species profiling reveals taxon-specific TE expansions accompanied by KZFP co-option and functional impacts in ruminants
- First Published March 23, 2026
Method
High-resolution genotype-free mapping of genetic variation with CRI-SPA-Map
- First Published March 23, 2026
Method
Complete genetic and epigenetic architecture of D4Z4 macrosatellites in FSHD, BAMS, and reference cohorts with D4Z4End2End
- First Published March 23, 2026
Method
Restoring the potency of a neutralizing antibody via guided hypermutation with hyper-antibody editor HAE1
- First Published March 19, 2026