Table of Contents

February 2026; 36 (2)

Review

  • Recent advances in methods to characterize archaic introgression in modern humans

    • David Peede,
    • Mayra M. Bañuelos,
    • Jazeps Medina Tretmanis,
    • Miriam Miyagi,
    • and Emilia Huerta-Sánchez
    Genome Res. February 2026 36: 239-256; Published in Advance January 16, 2026, doi:10.1101/gr.278993.124
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Research

  • Transcription and potential functions of a novel XIST isoform in male peripheral glia

    • Kevin S. O'Leary,
    • Meng-Yen Li,
    • Kevyn Jackson,
    • Lijie Shi,
    • Elena Ezhkova,
    • Bernice E. Morrow,
    • and Deyou Zheng
    Genome Res. February 2026 36: 257-274; Published in Advance December 12, 2025, doi:10.1101/gr.280832.125
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  • Transcriptomic landscape of transposable elements reveals LTR7-PLAAT4 as a potential oncogene and therapeutic target in pancreatic adenocarcinoma

    • Meilong Shi,
    • Chuanqi Teng,
    • Shan Zhang,
    • Xiaobo He,
    • Lingyun Xu,
    • Fengxian Han,
    • Rongqi Wen,
    • Ganjun Yu,
    • Jingwen Liu,
    • Yang Feng,
    • Yanfeng Wu,
    • Yan Ren,
    • Gang Jin,
    • and Jing Li
    Genome Res. February 2026 36: 275-290; Published in Advance January 8, 2026, doi:10.1101/gr.280528.125
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  • Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells

    • Marcel Tarbier,
    • Sebastian D. Mackowiak,
    • Vaishnovi Sekar,
    • Franziska Bonath,
    • Etka Yapar,
    • Bastian Fromm,
    • Omid R. Faridani,
    • Inna Biryukova,
    • and Marc R. Friedländer
    Genome Res. February 2026 36: 291-302; Published in Advance January 12, 2026, doi:10.1101/gr.279914.124
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  • MHC in newts illuminates the evolutionary dynamics of complex regions in giant genomes

    • Wiesław Babik,
    • Katarzyna Dudek,
    • Gemma Palomar,
    • Marzena Marszałek,
    • Grzegorz Dubin,
    • Maximina H. Yun,
    • and Magdalena Migalska
    Genome Res. February 2026 36: 303-317; Published in Advance January 12, 2026, doi:10.1101/gr.281127.125

  • Stable genome structures in living fossil fishes

    • Cheng Wang,
    • Chase D. Brownstein,
    • Wenjun Chen,
    • Zufa Ding,
    • Dan Yu,
    • Yu Deng,
    • Chenguang Feng,
    • Thomas J. Near,
    • Shunping He,
    • and Liandong Yang
    Genome Res. February 2026 36: 318-329; Published in Advance January 13, 2026, doi:10.1101/gr.280800.125

Methods

  • The oligogenic inheritance test GCOD detects risk genes and their interactions in congenital heart defects

    • Maureen Pittman,
    • Kihyun Lee,
    • Franco Felix,
    • Yu Huang,
    • Adrienne Lam,
    • Mauro W. Costa,
    • Deepak Srivastava,
    • and Katherine S. Pollard
    Genome Res. February 2026 36: 330-347; Published in Advance December 12, 2025, doi:10.1101/gr.281141.125
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  • Autoencoders for genomic variation analysis

    • Margarita Geleta,
    • Daniel Mas Montserrat,
    • Xavier Giro-i-Nieto,
    • and Alexander G. Ioannidis
    Genome Res. February 2026 36: 348-360; Published in Advance January 20, 2026, doi:10.1101/gr.280086.124
    OPEN ACCESS ARTICLE

  • A scalable computational framework for predicting gene expression from candidate cis-regulatory elements

    • Qinhu Zhang,
    • Siguo Wang,
    • Zhipeng Li,
    • Wenzheng Bao,
    • Wenjian Liu,
    • and De-Shuang Huang
    Genome Res. February 2026 36: 361-374; Published in Advance January 16, 2026, doi:10.1101/gr.281219.125
    OPEN ACCESS ARTICLE

  • Quantifying pathological progression from single-cell transcriptomic data with scPSS

    • Samin Rahman Khan,
    • M Saifur Rahman,
    • M. Sohel Rahman,
    • and Md Abul Hassan Samee
    Genome Res. February 2026 36: 375-386; Published in Advance January 14, 2026, doi:10.1101/gr.280411.125

  • scSHEFT enables multiomics label transfer from scRNA-seq to scATAC-seq through dual alignment

    • Zhitao Huang,
    • Ruiqing Zheng,
    • Pengzhen Jia,
    • Xuhua Yan,
    • Jinmiao Chen,
    • and Min Li
    Genome Res. February 2026 36: 387-396; Published in Advance January 20, 2026, doi:10.1101/gr.280410.125

  • Partitioned multi-MUM finding for scalable pangenomics with MumemtoM

    • Vikram S. Shivakumar and
    • Ben Langmead
    Genome Res. February 2026 36: 397-404; Published in Advance November 7, 2025, doi:10.1101/gr.280940.125

  • Strain-level metagenomic profiling using pangenome graphs with PanTax

    • Wenhai Zhang,
    • Yuansheng Liu,
    • Guangyi Li,
    • Jialu Xu,
    • Enlian Chen,
    • Alexander Schönhuth,
    • and Xiao Luo
    Genome Res. February 2026 36: 405-420; Published in Advance January 14, 2026, doi:10.1101/gr.280858.125
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Resource

  • The SynMall resource for characterizing the functional impact of synonymous variation

    • Chen Ye,
    • Xiaoyan Li,
    • Na Cheng,
    • Yansen Su,
    • and Junfeng Xia
    Genome Res. February 2026 36: 421-431; Published in Advance December 17, 2025, doi:10.1101/gr.281257.125

Corrigendum

  • Corrigendum: Machine learning identifies activation of RUNX/AP-1 as drivers of mesenchymal and fibrotic regulatory programs in gastric cancer

    • Milad Razavi-Mohseni,
    • Weitai Huang,
    • Yu A. Guo,
    • Dustin Shigaki,
    • Shamaine Wei Ting Ho,
    • Patrick Tan,
    • Anders J. Skanderup,
    • and Michael A. Beer
    Genome Res. February 2026 36: 432; doi:10.1101/gr.281294.125
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This Issue

February 2026; 36 (2)
Cover
  1. Review
  2. Research
  3. Methods
  4. Resource
  5. Corrigendum

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