RESEARCH

Alternate Polyadenylation in Human mRNAs: A Large-Scale Analysis by EST Clustering

• First Published May 1, 1998

LETTER

Bacterial Contig Map of the 21q11 Region Associated with Alzheimer’s Disease and Abnormal Myelopoiesis in Down Syndrome

• First Published April 1, 1998

INSIGHT/OUTLOOK

The Beautifully Simple but Intriguingly Complex World of Small Genomes

• First Published April 1, 1998

GENOME METHODS

Modification of Bacterial Artificial Chromosome Clones Using Cre Recombinase: Introduction of Selectable Markers for Expression in Eukaryotic Cells

• First Published April 1, 1998

LETTER

GLC1A Glaucoma Genes" > Characterization and Comparison of the Human and MouseGLC1A Glaucoma Genes

• First Published April 1, 1998

GENOME METHODS

Xenoduplex Analysis—A Method for Comparative Gene Mapping Using Hybrid Panels

• First Published April 1, 1998

PERSPECTIVE

The Context of Human Genetic Evolution

• First Published April 1, 1998

RESEARCH

Multiple Members of a Third Subfamily of P-Type ATPases Identified by Genomic Sequences and ESTs

• First Published April 1, 1998

INSIGHT/OUTLOOK

WebWise: Guide to the Institute of Molecular Biology Genome Sequencing Center—Jena Web Site

• First Published April 1, 1998

RESEARCH

Analysis of EST-Driven Gene Annotation in Human Genomic Sequence

• First Published April 1, 1998

RESEARCH

Caenorhabditis elegans by Comparative Sequence Analysis and Homology Modeling" > New Insulin-Like Proteins with Atypical Disulfide Bond Pattern Characterized in Caenorhabditis elegans by Comparative Sequence Analysis and Homology Modeling

• First Published April 1, 1998

RESEARCH

Computational Advances in Maximum Likelihood Methods for Molecular Phylogeny

• First Published March 1, 1998

Letter

EbEST: An Automated Tool Using Expressed Sequence Tags to Delineate Gene Structure

• First Published March 1, 1998

Letter

Estimation of Errors in “Raw” DNA Sequences: A Validation Study

• First Published March 1, 1998

Letter

Kaleidaseq: A Web-Based Tool to Monitor Data Flow in a High Throughput Sequencing Facility

• First Published March 1, 1998

INSIGHT/OUTLOOK

Late-Night Thoughts on the Sequence Annotation Problem

• First Published March 1, 1998

Letter

BioViews: Java-Based Tools for Genomic Data Visualization

• First Published March 1, 1998

RESEARCH

Phred. I. Accuracy Assessment" > Base-Calling of Automated Sequencer Traces UsingPhred. I. Accuracy Assessment

• First Published March 1, 1998

Letter

Identification of Human Gene Core Promoters in Silico

• First Published March 1, 1998

Letter

SeqHelp: A Program to Analyze Molecular Sequences Utilizing Common Computational Resources

• First Published March 1, 1998

Letter

Alternative Gene Form Discovery and Candidate Gene Selection from Gene Indexing Projects

• First Published March 1, 1998

INSIGHT/OUTLOOK

Base Qualities Help Sequencing Software

• First Published March 1, 1998

Editor's Note

Editor’s Note

• First Published March 1, 1998

RESEARCH

Phred. II. Error Probabilities" > Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities

• First Published March 1, 1998

Phylogenomics: Improving Functional Predictions for Uncharacterized Genes by Evolutionary Analysis

• First Published March 1, 1998

RESEARCH

GAIA: Framework Annotation of Genomic Sequence

• First Published March 1, 1998

RESEARCH

Reconstruction of Amino Acid Biosynthesis Pathways from the Complete Genome Sequence

• First Published March 1, 1998

INSIGHT/OUTLOOK

WebWise: Guide to the Baylor College of Medicine Human Genome Sequencing Center’s Web Site

• First Published March 1, 1998

RESEARCH

Software for Constructing and Verifying Pedigrees within Large Genealogies and an Application to the Old Order Amish of Lancaster County

• First Published March 1, 1998

RESEARCH

Consed: A Graphical Tool for Sequence Finishing" > Consed: A Graphical Tool for Sequence Finishing

• First Published March 1, 1998

Letter

Sequence Assembly with CAFTOOLS

• First Published March 1, 1998

RESEARCH

Physical and Genetic Mapping of the Human X Chromosome Centromere: Repression of Recombination

• First Published February 1, 1998

LETTER

Leishmania majorFriedlin Genome" > A Physical Map of the Leishmania majorFriedlin Genome

• First Published February 1, 1998

INSIGHT/OUTLOOK

ArabidopsisGenome Sequencing " > Opportunities and Challenges Grow from ArabidopsisGenome Sequencing

• First Published February 1, 1998

REVIEW

Tetrahymena thermophila " > Mapping the Germ-Line and Somatic Genomes of a Ciliated Protozoan,Tetrahymena thermophila

• First Published February 1, 1998

RESEARCH

The Distribution of Variation in Regulatory Gene Segments, as Present in MHC Class II Promoters

• First Published February 1, 1998

INSIGHT/OUTLOOK

WebWise: Guide to the Stanford Human Genome Center and the Whitehead/MIT Genome Center Web Sites

• First Published February 1, 1998

LETTER

Integrated YAC Contig Map of the Prader–Willi/Angelman Region on Chromosome 15q11–q13 with Average STS Spacing of 35 kb

• First Published February 1, 1998

RESEARCH

Allele Frequency Distributions in Pooled DNA Samples: Applications to Mapping Complex Disease Genes

• First Published February 1, 1998

INSIGHT/OUTLOOK

Why Is the Centromere So Cold?

• First Published February 1, 1998

LETTER

Contig Maps and Genomic Sequencing Identify Candidate Genes in the Usher 1C Locus

• First Published January 1, 1998

LETTER

A Gene Map of the Best’s Vitelliform Macular Dystrophy Region in Chromosome 11q12–q13.1

• First Published January 1, 1998

RESEARCH

Comparative Sequence Analysis of a Gene-Rich Cluster at Human Chromosome 12p13 and its Syntenic Region in Mouse Chromosome 6

• First Published January 1, 1998

INSIGHT/OUTLOOK

Speciation, Chromosomes, and Genomes

• First Published January 1, 1998

RESEARCH

Armigeres subalbatus Using Aedes aegyptiRFLP Markers" > Development of a Comparative Genetic Linkage Map for Armigeres subalbatus Using Aedes aegyptiRFLP Markers

• First Published January 1, 1998

METHODS

High-Precision Genotyping by Denaturing Capillary Electrophoresis

• First Published January 1, 1998

REVIEW

Zebrafish: Genomics on the Fast Track

• First Published January 1, 1998

INSIGHT/OUTLOOK

WebWise: Guide to The Sanger Center’s Web Site

• First Published January 1, 1998

RESEARCH

Toxoplasma gondiiReveals Sequences Restricted to the Apicomplexa" > Gene Discovery by EST Sequencing in Toxoplasma gondiiReveals Sequences Restricted to the Apicomplexa

• First Published January 1, 1998

INSIGHT/OUTLOOK

Man to Mouse—Lessons Learned from the Distal End of the Human X Chromosome

• First Published December 1, 1997

RESEARCH

Fugu rubripes and their Association with CpG-Rich Islands" > The Comparative Genomic Structure and Sequence of the Surfeit Gene Homologs in the Puffer Fish Fugu rubripes and their Association with CpG-Rich Islands

• First Published December 1, 1997

LETTER

Genome Mapping by Fluorescent Fingerprinting

• First Published December 1, 1997

LETTER

Cloning-Free PCR-Based Allele Replacement Methods

• First Published December 1, 1997

REVIEW

Zooming in on the Human–Mouse Comparative Map: Genome Conservation Re-examined on a High-Resolution Scale

• First Published December 1, 1997

INSIGHT/OUTLOOK

WebWise: The Washington University Genome Sequencing Center’s Web Site

• First Published December 1, 1997

LETTER

A First-Generation Whole Genome–Radiation Hybrid Map Spanning the Mouse Genome

• First Published December 1, 1997

LETTER

Saccharomyces cerevisiae in a Readily Usable Form" > The Complete Set of Predicted Genes from Saccharomyces cerevisiae in a Readily Usable Form

• First Published December 1, 1997

INSIGHT/OUTLOOK

Sequence Ready—or Not?

• First Published December 1, 1997

INSIGHT/OUTLOOK

Do These Sequences Make CENs Yet?

• First Published November 1, 1997

GENOME METHODS

A Streamlined Mutation Detection System: Multicolor Post-PCR Fluorescence Labeling and Single-Strand Conformational Polymorphism Analysis by Capillary Electrophoresis

• First Published November 1, 1997

REVIEW

The Importance of Fungi to Man

• First Published November 1, 1997

INSIGHT/OUTLOOK

WebWise: Navigating the Human Genome Project

• First Published November 1, 1997

LETTER

Genetic Mapping of 262 Loci Derived from Expressed Sequences in a Murine Interspecific Cross Using Single-Strand Conformational Polymorphism Analysis

• First Published November 1, 1997

RESEARCH

Arabidopsis thaliana Centromere Regions: Genetic Map Positions and Repetitive DNA Structure" > Arabidopsis thaliana Centromere Regions: Genetic Map Positions and Repetitive DNA Structure

• First Published November 1, 1997

LETTER

High Throughput Fingerprint Analysis of Large-Insert Clones

• First Published November 1, 1997

LETTER

AluInsertion Polymorphisms and Human Evolution: Evidence for a Larger Population Size in Africa " > AluInsertion Polymorphisms and Human Evolution: Evidence for a Larger Population Size in Africa

• First Published November 1, 1997

RESEARCH

Steady-State Transcript Levels of the Porphobilinogen Deaminase Gene in Patients with Acute Intermittent Porphyria

• First Published November 1, 1997

GENOME METHODS

A Simple Method for Automated Allele Binning in Microsatellite Markers

• First Published November 1, 1997

INSIGHT/OUTLOOK

Gaucher Disease Phenotypes Outflanked?

• First Published October 1, 1997

LETTER

The Largest Subunit of Human RNA Polymerase III Is Closely Related to the Largest Subunit of Yeast and Trypanosome RNA Polymerase III

• First Published October 1, 1997

INSIGHT/OUTLOOK

When the Chips are Down

• First Published October 1, 1997

RESEARCH

The Significance of Digital Gene Expression Profiles

• First Published October 1, 1997

INSIGHT/OUTLOOK

Modeling Human Evolution—To Tree or Not to Tree?

• First Published October 1, 1997

LETTER

Detection of Numerous Y Chromosome Biallelic Polymorphisms by Denaturing High-Performance Liquid Chromatography

• First Published October 1, 1997

LETTER

Identification of Three Additional Genes Contiguous to the Glucocerebrosidase Locus on Chromosome 1q21: Implications for Gaucher Disease

• First Published October 1, 1997

METHODS

IMAGE cDNA Clones, UniGene Clustering, and ACeDB: An Integrated Resource for Expressed Sequence Information

• First Published October 1, 1997

INSIGHT/OUTLOOK

Database Divisions and Homology Search Files: A Guide for the Perplexed

• First Published October 1, 1997

RESEARCH

Caenorhabditis elegans " > Interpreting a Sequenced Genome: Toward a Cosmid Transgenic Library ofCaenorhabditis elegans

• First Published October 1, 1997

REVIEW

The Role of Genomics in Studying Genetic Susceptibility to Infectious Disease

• First Published October 1, 1997

PERSPECTIVE

Long Human–Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse Genome

• First Published October 1, 1997

RESEARCH

High-Resolution Mapping and Transcript Identification at the Progressive Epilepsy with Mental Retardation Locus on Chromosome 8p

• First Published September 1, 1997

RESEARCH

DFNB7 andDFNB11 Region of Chromosome 9q13–21" > Construction of P1-Derived Artificial Chromosome and Yeast Artificial Chromosome Contigs Encompassing the DFNB7 andDFNB11 Region of Chromosome 9q13–21

• First Published September 1, 1997

LETTER

Characterization of Short Tandem Repeats from Thirty-One Human Telomeres

• First Published September 1, 1997

REVIEW

Eukaryotic Promoter Recognition

• First Published September 1, 1997

LETTER

CpG Islands of the Pig

• First Published September 1, 1997

INSIGHT/OUTLOOK

Closing in on Telomeric Closure

• First Published September 1, 1997

INSIGHT/OUTLOOK

More BLAST for the Buck

• First Published September 1, 1997

RESEARCH

A Radiation Hybrid Map of Human Chromosome 5 with Integration of Cytogenetic, Genetic, and Transcript Maps

• First Published September 1, 1997

RESEARCH

myostatin (GDF8) in Double-Muscled Belgian Blue and Piedmontese Cattle" > Mutations in myostatin (GDF8) in Double-Muscled Belgian Blue and Piedmontese Cattle

• First Published September 1, 1997

CORRECTION

Corrections for vol. 7, p. 522

• First Published September 1, 1997

INSIGHT/OUTLOOK

Plant Genomics Moves into the Limelight

• First Published September 1, 1997

LETTER

Cloning, Characterization, and Mapping of a Murine Promiscuous Chemokine Receptor Gene: Homolog of the Human Duffy Gene

• First Published September 1, 1997

INSIGHT/OUTLOOK

Small Open Reading Frames: Beautiful Needles in the Haystack

• First Published August 1, 1997

RESEARCH

Mycobacterium leprae Genome" > Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome

• First Published August 1, 1997

RESEARCH

A High-Resolution Physical and Transcript Map of the Cri du Chat Region of Human Chromosome 5p

• First Published August 1, 1997

RESEARCH

High-Resolution Physical and Transcriptional Mapping of the Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy Locus on Chromosome 21q22.3 by FISH

• First Published August 1, 1997

INSIGHT/OUTLOOK

Rare Disease Genes—Lessons and Challenges

• First Published August 1, 1997

LETTER

A Locus for Autosomal Recessive Pseudoxanthoma Elasticum, with Penetrance of Vascular Symptoms in Carriers, Maps to Chromosome 16p13.1

• First Published August 1, 1997

GENOME METHODS

Pfu DNA Polymerase on a Human Mitochondrial DNA Sequence" > Fidelity and Mutational Spectrum of Pfu DNA Polymerase on a Human Mitochondrial DNA Sequence

• First Published August 1, 1997

REVIEW

Recombination Hot Spots and Human Disease

• First Published August 1, 1997