Volume 36, Issue 8 | August 2026

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In memoriam
- - Jim Watson (1928–2025): a genomics visionary
    Aravinda Chakravarti
    Evan E. Eichler
    Anne C. Ferguson-Smith
    Richard A. Gibbs
    Eric D. Green
    John R. Inglis
    Kateryna D. Makova
    Richard M. Myers
    Hillary E. Sussman
    First Published July 23, 2026
Research
- - An RNA polymerase III tissue and tumor atlas uncovers context-specific activities linked to 3D epigenome regulatory mechanisms
    Simon Lizarazo
    Sihang Zhou
    Ruiying Cheng
    Rajendra K C
    Saindhabi Ghosh
    Yawei Shen
    Qing Liu
    Kevin Van Bortle
    First Published July 13, 2026
  - Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture
    Kate Liddiard
    Emmon Coral
    Harsh Bhatt
    Kez Cleal
    Duncan M. Baird
    First Published June 29, 2026
  - Resf1 is required for proper placental development and configuration of trophoblast cell–specific heterochromatin
    Kei Fukuda
    Kimiko Inoue
    Chikako Shimura
    Moe Kitazawa
    Michiko Hirose
    Takashi Ishiuchi
    Shogo Matoba
    Atsuo Ogura
    Yoichi Shinkai
    First Published June 29, 2026
  - Covariation of genetic and epigenetic divergence in barn swallows
    Sarah A. Mueller
    Uthara Srinivasan
    Zachary M. Laubach
    Drew R. Schield
    Jan A.C. von Rönn
    Rebecca J. Safran
    Jochen B.W. Wolf
    First Published June 16, 2026
  - Genome-wide crossover analysis in the holocentric pantry moth reveals strong crossover assurance and interference during spermatogenesis
    LingSze Lee
    Apratim Mitra
    Leif Benner
    Melania Bruno
    Lorielle M. Raab
    Rose K. Runyan
    Emma Smith
    Ryan K. Dale
    Leah F. Rosin
    First Published July 16, 2026
  - Evolution of an adaptive, inducible defensive trait in a model crustacean
    Zhixiong Deng
    Sen Xu
    Dengqing Li
    Guo Yu
    Swatantra Neupane
    Li Wang
    ...[+1 authors]...,
    David Blair
    Wei Hu
    Adam Petrusek
    Mingbo Yin
    First Published June 5, 2026
  - Elevated DNA insertion rate in Cyanophora paradoxa reveals unique repair signature
    Marc Krasovec
    Anna Lipzen
    Nigel Grimsley
    Gilles Mirambeau
    Kerrie Barry
    Igor V. Grigoriev
    Gwenael Piganeau
    First Published June 12, 2026
Methods
- - A comparison of ancient DNA yields across ossicles and the petrous bone reveals the best preservation in the stapes and incus
    Ekin Sağlıcan
    Arda Sevkar
    Duygu Deniz Kazancı
    Gonzalo Oteo-García
    Sevgi Yorulmaz
    Kıvılcım Başak Vural Gökhan Çakan Gökçen Adiloğlu Duru Buldak Güneş Duru Aliye Öztan Brenna Hassett Nurcan Kayacan Aslı Erim Özdoğan Anders Götherström
    ...[+10 authors]...,
    Füsun Özer
    Ömür Dilek Erdal
    Yılmaz Selim Erdal
    Mehmet Somel
    First Published June 11, 2026
  - Biobank-scale genotype similarity search and dynamic patient-matched cohort creation with GenoSiS
    Kristen Schneider
    Murad Chowdhury
    Mariano Tepper
    Jawad B. Khan
    Jonathan A. Shortt
    Chris Gignoux
    Ryan M. Layer
    First Published July 10, 2026
  - Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI
    Peimeng Zhen
    Han Shu
    Bingtao Wang
    Yongtian Wang
    Jialu Hu
    Jiajie Peng
    Xuequn Shang
    Tao Wang
    Jing Chen
    First Published July 22, 2026
  - ComicGTN infers disease-associated rare cell states from single-cell multiomic data using DNA sequence–augmented graph transformer networks
    Boran Yang
    Jiao Hua
    Guanghua Zhou
    Yuhui Feng
    Jing Qi
    Yiyuan Guo
    Danshu Sheng
    Shuilin Jin
    First Published July 17, 2026
  - Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks
    Zihuan Du
    Xiaoyu Zhang
    Qiang Zhang
    Jing Li
    Zhijie Cao
    Ge Gao
    Tao Lin
    Dong Wang
    Shuai Gao
    First Published July 22, 2026
  - A unified analysis of cell-type- and trajectory-associated pathways in single-cell data using Phoenix
    Yudit Halperin
    Daphna Nachmani
    Michal Rabani
    First Published June 29, 2026
Resources
- - Complete sequencing of medaka genomes reveals the architecture of centromeric satellites, giant mobile elements, and sex chromosomes
    Yoshihiko Suzuki
    Kazuki Ichikawa
    Yusuke Inoue
    Chie Owa
    Haruka Kobayashi
    Kenji Morikami Ryohei Nakamura Takafumi Ikeda Manabu Fujie Mayumi Kawamitsu Nana Arakaki Eugene W. Myers Hiroyuki Aburatani Yusuke Takehana Masaru Matsuda
    ...[+10 authors]...,
    Kiyoshi Naruse
    Shigehiro Kuraku
    Hiroyuki Takeda
    Shinichi Morishita
    First Published July 1, 2026
  - Tracing genome size dynamics in sharks and rays with inclusive sequence analysis by the Squalomix Consortium
    Shigehiro Kuraku
    Yawako W. Kawaguchi
    Taiki Niwa
    Ryo Misawa
    Yohey Ogawa
    Mitsutaka Kadota Kazuhiro Saito Waichiro Godo Tatsuya Sakamoto
    ...[+4 authors]...,
    Wataru Takagi
    Sachiko Isobe
    Kenta Shirasawa
    Akane Kawaguchi
    First Published June 16, 2026

Table of Contents

Volume 36, Issue 8 | August 2026

In memoriam

Jim Watson (1928–2025): a genomics visionary

Research

An RNA polymerase III tissue and tumor atlas uncovers context-specific activities linked to 3D epigenome regulatory mechanisms

Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture

Resf1 is required for proper placental development and configuration of trophoblast cell–specific heterochromatin

Covariation of genetic and epigenetic divergence in barn swallows

Genome-wide crossover analysis in the holocentric pantry moth reveals strong crossover assurance and interference during spermatogenesis

Evolution of an adaptive, inducible defensive trait in a model crustacean

Elevated DNA insertion rate in Cyanophora paradoxa reveals unique repair signature

Methods

A comparison of ancient DNA yields across ossicles and the petrous bone reveals the best preservation in the stapes and incus

Biobank-scale genotype similarity search and dynamic patient-matched cohort creation with GenoSiS

Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI

ComicGTN infers disease-associated rare cell states from single-cell multiomic data using DNA sequence–augmented graph transformer networks

Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks

A unified analysis of cell-type- and trajectory-associated pathways in single-cell data using Phoenix

Resources

Complete sequencing of medaka genomes reveals the architecture of centromeric satellites, giant mobile elements, and sex chromosomes

Tracing genome size dynamics in sharks and rays with inclusive sequence analysis by the Squalomix Consortium

Table of Contents

Volume 36, Issue 8 | August 2026

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In memoriam

Research

Methods

Resources