Volume 11, Issue 8 | August 2001

INSIGHT/OUTLOOK
- - The Search for Meaning in Noncoding DNA
    Andrew G. Clark
    First Published August 1, 2001
  - Transposon-Induced Hotspots for Genomic Instability
    Margaret G. Kidwell
    Andrew J. Holyoake
    First Published August 1, 2001
  - SAGE Thoughts on Aging
    Thomas E. Johnson
    First Published August 1, 2001
ARTICLES
- - Gene Targeting of Desrt, a Novel ARID Class DNA-Binding Protein, Causes Growth Retardation and Abnormal Development of Reproductive Organs
    Mireille H. Lahoud
    Sika Ristevski
    Deon J. Venter
    Lars S. Jermiin
    Ivan Bertoncello
    Silva Zavarsek Sue Hasthorpe
    ...[+2 authors]...,
    John Drago
    David de Kretser
    Paul J. Hertzog
    Ismail Kola
    First Published July 12, 2001
  - Analysis of Conserved Noncoding DNA in Drosophila Reveals Similar Constraints in Intergenic and Intronic Sequences
    Casey M. Bergman
    Martin Kreitman
    First Published August 1, 2001
  - Changes in Gene Expression Associated with Developmental Arrest and Longevity in Caenorhabditis elegans
    Steven J.M. Jones
    Donald L. Riddle
    Anatoli T. Pouzyrev
    Victor E. Velculescu
    LaDeana Hillier
    Sean R. Eddy
    ...[+1 authors]...,
    Shawn L. Stricklin
    David L. Baillie
    Robert Waterston
    Marco A. Marra
    First Published July 12, 2001
LETTERS
- - Molecular Characterization of Two Natural Hotspots in the Drosophila buzzatii Genome Induced by Transposon Insertions
    Mario Cáceres
    Marta Puig
    Alfredo Ruiz
    First Published July 12, 2001
  - Prokaryotic Homologs of the Eukaryotic DNA-End-Binding Protein Ku, Novel Domains in the Ku Protein and Prediction of a Prokaryotic Double-Strand Break Repair System
    L. Aravind
    Eugene V. Koonin
    First Published August 1, 2001
  - Divergence of Function in Sequence-Related Groups of Escherichia coli Proteins
    Laila Alves Nahum
    Monica Riley
    First Published August 1, 2001
  - Sequence Variation Within the Fragile X Locus
    Debra J. Mathews
    Carl Kashuk
    Gale Brightwell
    Evan E. Eichler
    Aravinda Chakravarti
    First Published August 1, 2001
  - Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs
    Yongtao Yu
    Chenggang Zhang
    Gangqiao Zhou
    Songfeng Wu
    Xianghu Qu
    Handong Wei Guichun Xing Chunna Dong Yun Zhai Jinghong Wan Shuguang Ouyang Li Li Shaowen Zhang
    ...[+8 authors]...,
    Kaixin Zhou
    Yinan Zhang
    Chutse Wu
    Fuchu He
    First Published August 1, 2001
METHODS
- - Capturing Whole-Genome Characteristics in Short Sequences Using a Naïve Bayesian Classifier
    Rickard Sandberg
    Gösta Winberg
    Carl-Ivar Bränden
    Alexander Kaske
    Ingemar Ernberg
    First Published August 1, 2001
  - Prediction of Protein Functional Domains from Sequences Using Artificial Neural Networks
    János Murvai
    Kristian Vlahoviček
    Csaba Szepesvári
    Sándor Pongor
    First Published August 1, 2001
  - Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation
    Shoulian Dong
    Eugene Wang
    Linda Hsie
    Yanxiang Cao
    Xiaogiong Chen
    First Published July 12, 2001
RESOURCES
- - Creating the Gene Ontology Resource: Design and Implementation
    The Gene Ontology Consortium
    First Published August 1, 2001
  - A Marker-Dense Physical Map of the Bradyrhizobium japonicum Genome
    Jeffrey P. Tomkins
    Todd C. Wood
    Minviluz G. Stacey
    John T. Loh
    Adam Judd
    First Published August 1, 2001
  - Computational and Experimental Analysis of Microsatellites in Rice (Oryza sativa L.): Frequency, Length Variation, Transposon Associations, and Genetic Marker Potential
    Svetlana Temnykh
    Genevieve DeClerck
    Angelika Lukashova
    Leonard Lipovich
    Samuel Cartinhour
    First Published August 1, 2001
  - Virtual Genome Scan: A Tool for Restriction Landmark-Based Scanning of the Human Genome
    Jean-Marie Rouillard
    Ayse E. Erson
    Rork Kuick
    Jun-ichi Asakawa
    Katharina Wimmer
    First Published July 12, 2001

Table of Contents

Volume 11, Issue 8 | August 2001

INSIGHT/OUTLOOK

The Search for Meaning in Noncoding DNA

Transposon-Induced Hotspots for Genomic Instability

SAGE Thoughts on Aging

ARTICLES

Gene Targeting of Desrt, a Novel ARID Class DNA-Binding Protein, Causes Growth Retardation and Abnormal Development of Reproductive Organs

Analysis of Conserved Noncoding DNA in Drosophila Reveals Similar Constraints in Intergenic and Intronic Sequences

Changes in Gene Expression Associated with Developmental Arrest and Longevity in Caenorhabditis elegans

LETTERS

Molecular Characterization of Two Natural Hotspots in the Drosophila buzzatii Genome Induced by Transposon Insertions

Prokaryotic Homologs of the Eukaryotic DNA-End-Binding Protein Ku, Novel Domains in the Ku Protein and Prediction of a Prokaryotic Double-Strand Break Repair System

Divergence of Function in Sequence-Related Groups of Escherichia coli Proteins

Sequence Variation Within the Fragile X Locus

Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs

METHODS

Capturing Whole-Genome Characteristics in Short Sequences Using a Naïve Bayesian Classifier

Prediction of Protein Functional Domains from Sequences Using Artificial Neural Networks

Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation

RESOURCES

Creating the Gene Ontology Resource: Design and Implementation

A Marker-Dense Physical Map of the Bradyrhizobium japonicum Genome

Computational and Experimental Analysis of Microsatellites in Rice (Oryza sativa L.): Frequency, Length Variation, Transposon Associations, and Genetic Marker Potential

Virtual Genome Scan: A Tool for Restriction Landmark-Based Scanning of the Human Genome

Table of Contents

Volume 11, Issue 8 | August 2001

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INSIGHT/OUTLOOK

ARTICLES

LETTERS

METHODS

RESOURCES