Your search for returned 6,372 results
Method
Cancer-associated dynamics and potential regulators of intronic polyadenylation revealed by IPAFinder using standard RNA-seq data
- First Published September 2, 2021
Research
Nuclease deficiencies alter plasma cell-free DNA methylation profiles
- First Published September 1, 2021
Method
Inferring genes that escape X-Chromosome inactivation reveals important contribution of variable escape genes to sex-biased diseases
- First Published August 23, 2021
Research
Crossover-active regions of the wheat genome are distinguished by DMC1, the chromosome axis, H3K27me3, and signatures of adaptation
- First Published August 23, 2021
Resource
A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells
- First Published August 23, 2021
Method
Variational inference using approximate likelihood under the coalescent with recombination
- First Published August 23, 2021
Research
Mutational bias in spermatogonia impacts the anatomy of regulatory sites in the human genome
- First Published August 20, 2021
Method
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi
- First Published August 18, 2021
Research
The human ribosomal DNA array is composed of highly homogenized tandem clusters
- First Published August 18, 2021
Resource
Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination" > A systematic analysis of Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination
- First Published August 18, 2021
Research
Ligand-induced native G-quadruplex stabilization impairs transcription initiation
- First Published August 16, 2021
Research
Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brain
- First Published August 16, 2021
Resource
Drosophila ovaries" > A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries
- First Published August 13, 2021
Resource
Small RNA expression and miRNA modification dynamics in human oocytes and early embryos
- First Published August 2, 2021
Resource
Global patterns of enhancer activity during sea urchin embryogenesis assessed by eRNA profiling
- First Published July 30, 2021
Research
Parental methylome reprogramming in human uniparental blastocysts reveals germline memory transition
- First Published July 30, 2021
Research
Differences in the number of de novo mutations between individuals are due to small family-specific effects and stochasticity
- First Published July 23, 2021
Research
Genome-wide variability in recombination activity is associated with meiotic chromatin organization
- First Published July 23, 2021
Method
Likelihood-based deconvolution of bulk gene expression data using single-cell references
- First Published July 22, 2021
Method
A graph neural network model to estimate cell-wise metabolic flux using single-cell RNA-seq data
- First Published July 22, 2021
Research
Single worm transcriptomics identifies a developmental core network of oscillating genes with deep conservation across nematodes
- First Published July 22, 2021
Research
Longitudinal linked-read sequencing reveals ecological and evolutionary responses of a human gut microbiome during antibiotic treatment
- First Published July 22, 2021
Research
Genomic architecture constrained placental mammal X Chromosome evolution
- First Published July 22, 2021
Research
Large palindromes on the primate X Chromosome are preserved by natural selection
- First Published July 21, 2021
Research
Enhancers with tissue-specific activity are enriched in intronic regions
- First Published July 21, 2021
Method
Sequence-based correction of barcode bias in massively parallel reporter assays
- First Published July 20, 2021
Method
cis-regulatory diversity in DNA regions" > A universal framework for detecting cis-regulatory diversity in DNA regions
- First Published July 19, 2021
Research
The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection
- First Published July 15, 2021
Method
Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
- First Published July 14, 2021
Research
Hydroxycarbamide effects on DNA methylation and gene expression in myeloproliferative neoplasms
- First Published July 9, 2021
Research
Genome-wide mapping reveals R-loops associated with centromeric repeats in maize
- First Published July 9, 2021
Research
Characterizing nucleotide variation and expansion dynamics in human-specific variable number tandem repeats
- First Published July 9, 2021
Method
A Bayesian inference transcription factor activity model for the analysis of single-cell transcriptomes
- First Published June 30, 2021
Research
Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome
- First Published June 29, 2021
Resource
Dictyostelium development" > Transcriptional milestones in Dictyostelium development
- First Published June 28, 2021
Research
Drosophila intestinal stem cells" > Evolution and genomic signatures of spontaneous somatic mutation in Drosophila intestinal stem cells
- First Published June 24, 2021
Research
Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes
- First Published June 23, 2021
Method
Haplotype diversity and sequence heterogeneity of human telomeres
- First Published June 23, 2021
Research
Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals
- First Published June 21, 2021
Method
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA
- First Published June 17, 2021
Research
The loss of heterochromatin is associated with multiscale three-dimensional genome reorganization and aberrant transcription during cellular senescence
- First Published June 17, 2021
Resource
Long-read RNA sequencing reveals widespread sex-specific alternative splicing in threespine stickleback fish
- First Published June 15, 2021
Method
Assessing conservation of alternative splicing with evolutionary splicing graphs
- First Published June 15, 2021
Research
Neisseria meningitidis" > The effect of recombination on the evolution of a population of Neisseria meningitidis
- First Published June 9, 2021
Method
Rapid and accurate alignment of nucleotide conversion sequencing reads with HISAT-3N
- First Published June 8, 2021
Research
A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes
- First Published June 4, 2021
Method
A machine learning method for the discovery of minimum marker gene combinations for cell type identification from single-cell RNA sequencing
- First Published June 4, 2021
Research
Arabidopsis" > Polycomb-dependent differential chromatin compartmentalization determines gene coregulation in Arabidopsis
- First Published June 3, 2021
Research
Conserved noncoding sequences provide insights into regulatory sequence and loss of gene expression in maize
- First Published May 27, 2021
Method
A joint deep learning model enables simultaneous batch effect correction, denoising, and clustering in single-cell transcriptomics
- First Published May 25, 2021
Method
Characterizing spatial gene expression heterogeneity in spatially resolved single-cell transcriptomic data with nonuniform cellular densities
- First Published May 25, 2021
Method
Analysis of alternative polyadenylation from single-cell RNA-seq using scDaPars reveals cell subpopulations invisible to gene expression
- First Published May 25, 2021
Resource
Drosophila brain on cocaine at single-cell resolution" > The Drosophila brain on cocaine at single-cell resolution
- First Published May 25, 2021
Method
Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories
- First Published May 19, 2021
Research
Positive selective sweeps of epigenetic mutations regulating specialized metabolites in plants
- First Published May 18, 2021
Research
CTCF looping is established during gastrulation in medaka embryos
- First Published May 18, 2021
Research
Chromatin architecture transitions from zebrafish sperm through early embryogenesis
- First Published May 18, 2021
Research
Distinct roles for RSC and SWI/SNF chromatin remodelers in genomic excision repair
- First Published May 17, 2021
Research
Competition for DNA binding between paralogous transcription factors determines their genomic occupancy and regulatory functions
- First Published May 11, 2021
Research
Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy
- First Published May 7, 2021
Research
The genomic basis of evolutionary differentiation among honey bees
- First Published May 4, 2021
Research
Toxoplasma gondii and Neospora caninum genomes reveals misassembly, karyotype differences, and chromosomal rearrangements" > Reevaluation of the Toxoplasma gondii and Neospora caninum genomes reveals misassembly, karyotype differences, and chromosomal rearrangements
- First Published April 27, 2021
Research
Toxoplasma gondii and related tissue coccidia" > A novel fragmented mitochondrial genome in the protist pathogen Toxoplasma gondii and related tissue coccidia
- First Published April 27, 2021
Research
Linking the dynamics of chromatin occupancy and transcription with predictive models
- First Published April 23, 2021
Resource
Caenorhabditis elegans nematodes" > Comprehensive characterization of tissue-specific chromatin accessibility in L2 Caenorhabditis elegans nematodes
- First Published April 22, 2021
Resource
Modeling transcriptional regulation of model species with deep learning
- First Published April 22, 2021
Research
Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands
- First Published April 20, 2021
Research
Enterprise, a massive transposon carrying Spok meiotic drive genes" > The Enterprise, a massive transposon carrying Spok meiotic drive genes
- First Published April 19, 2021
Research
Xenopus laevis" > Identification and characterization of centromeric sequences in Xenopus laevis
- First Published April 19, 2021
Method
Systematic evaluation of the effect of polyadenylation signal variants on the expression of disease-associated genes
- First Published April 19, 2021
Research
Genome-wide analysis of plant miRNA action clarifies levels of regulatory dynamics across developmental contexts
- First Published April 16, 2021
Research
The contributions from the progenitor genomes of the mesopolyploid Brassiceae are evolutionarily distinct but functionally compatible
- First Published April 16, 2021
Research
Copy number variation underlies complex phenotypes in domestic dog breeds and other canids
- First Published April 16, 2021
Research
Tissue-specific reprogramming of host tRNA transcriptome by the microbiome
- First Published April 15, 2021
Research
Drosophila fat body is infection-specific" > The mode of expression divergence in Drosophila fat body is infection-specific
- First Published April 15, 2021
Method
Profiling single-cell histone modifications using indexing chromatin immunocleavage sequencing
- First Published April 14, 2021
Method
Mapping the regulatory landscape of auditory hair cells from single-cell multi-omics data
- First Published April 9, 2021
Method
Bayesian estimation of cell type–specific gene expression with prior derived from single-cell data
- First Published April 9, 2021
Method
Automated quality control and cell identification of droplet-based single-cell data using dropkick
- First Published April 9, 2021
Method
Interpretation of allele-specific chromatin accessibility using cell state–aware deep learning
- First Published April 8, 2021
Resource
Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring
- First Published April 8, 2021
Method
Optimized sample selection for cost-efficient long-read population sequencing
- First Published April 2, 2021
Research
Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication
- First Published April 2, 2021
Research
Antisense RNAs during early vertebrate development are divided in groups with distinct features
- First Published April 1, 2021
Method
A HIT-trapping strategy for rapid generation of reversible and conditional alleles using a universal donor
- First Published April 1, 2021
Corrigendum
Corrigendum: Benchmark and integration of resources for the estimation of human transcription factor activities
- First Published April 1, 2021
Method
Fast decoding cell type–specific transcription factor binding landscape at single-nucleotide resolution
- First Published March 19, 2021
Method
Alignment of single-cell RNA-seq samples without overcorrection using kernel density matching
- First Published March 19, 2021
Method
Ultrafast functional profiling of RNA-seq data for nonmodel organisms
- First Published March 17, 2021
Method
Correcting signal biases and detecting regulatory elements in STARR-seq data
- First Published March 15, 2021