Table of Contents

INSIGHT/OUTLOOK

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A Chimpanzee Genome Project Is a Biomedical Imperative
- Ajit Varki
Genome Res. August 1, 2000 10: 1065-1070; doi:10.1101/gr.10.8.1065
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WABA Success: A Tool for Sequence Comparison between Large Genomes
- David L. Baillie and
- Ann M. Rose
Genome Res. August 1, 2000 10: 1071-1073; doi:10.1101/gr.10.8.1071
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Guilt by Association: Contextual Information in Genome Analysis
- L. Aravind
Genome Res. August 1, 2000 10: 1074-1077; doi:10.1101/gr.10.8.1074

REVIEW

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Automation for Genomics, Part One: Preparation for Sequencing
- Deirdre Meldrum
Genome Res. August 1, 2000 10: 1081-1092; doi:10.1101/gr.101400

REPORTS

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Genomic Sequence Analysis of the Mouse Naip Gene Array
- Matthew G. Endrizzi,
- Vey Hadinoto,
- Joseph D. Growney,
- Webb Miller,
- and William F. Dietrich
Genome Res. August 1, 2000 10: 1095-1102; doi:10.1101/gr.10.8.1095
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Gene Survey of the Pathogenic Protozoan Trypanosoma cruzi
- Betina M. Porcel,
- Anh-Nhi Tran,
- Martti Tammi,
- Zoltan Nyarady,
- Maria Rydåker,
- Turan P. Urmenyi,
- Edson Rondinelli,
- Ulf Pettersson,
- Bj̈orn Andersson,
- and Lena Åslund
Genome Res. August 1, 2000 10: 1103-1107; doi:10.1101/gr.10.8.1103
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GT Repeats Are Associated with Recombination on Human Chromosome 22
- Jacek Majewski and
- Jurg Ott
Genome Res. August 1, 2000 10: 1108-1114; doi:10.1101/gr.10.8.1108

ARTICLES

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Conservation, Regulation, Synteny, and Introns in a Large-scale C. briggsae–C. elegans Genomic Alignment
- W. James Kent and
- Alan M. Zahler
Genome Res. August 1, 2000 10: 1115-1125; doi:10.1101/gr.10.8.1115
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Genome-wide Detection of Allelic Imbalance Using Human SNPs and High-density DNA Arrays
- Rui Mei,
- Patricia C. Galipeau,
- Cynthia Prass,
- Anthony Berno,
- Ghassan Ghandour,
- Nila Patil,
- Roger K. Wolff,
- Mark S. Chee,
- Brian J. Reid,
- and David J. Lockhart
Genome Res. August 1, 2000 10: 1126-1137; doi:10.1101/gr.10.8.1126

LETTERS

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Discovery of a Novel, Paternally Expressed Ubiquitin-specific Processing Protease Gene through Comparative Analysis of an Imprinted Region of Mouse Chromosome 7 and Human Chromosome 19q13.4
- Joomyeong Kim,
- Vladimir N. Noskov,
- Xiaochen Lu,
- Anne Bergmann,
- Xiaojia Ren,
- Tiffany Warth,
- Paul Richardson,
- Natalya Kouprina,
- and Lisa Stubbs
Genome Res. August 1, 2000 10: 1138-1147; doi:10.1101/gr.10.8.1138
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Alfresco—A Workbench for Comparative Genomic Sequence Analysis
- Niclas Jareborg and
- Richard Durbin
Genome Res. August 1, 2000 10: 1148-1157; doi:10.1101/gr.10.8.1148
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High-resolution Genetic and Physical Map of the Lgn1 Interval in C57BL/6J Implicates Naip2 or Naip5 in Legionella pneumophila Pathogenesis
- Joseph D. Growney and
- William F. Dietrich
Genome Res. August 1, 2000 10: 1158-1171; doi:10.1101/gr.10.8.1158
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Eukaryote-specific Domains in Translation Initiation Factors: Implications for Translation Regulation and Evolution of the Translation System
- L. Aravind and
- Eugene V. Koonin
Genome Res. August 1, 2000 10: 1172-1184; doi:10.1101/gr.10.8.1172
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Ecologic Genomics of DNA: Upstream Bending in Prokaryotic Promoters
- Alexander Bolshoy and
- Eviatar Nevo
Genome Res. August 1, 2000 10: 1185-1193; doi:10.1101/gr.10.8.1185
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Genomic Sequence Analysis of Fugu rubripes CFTR and Flanking Genes in a 60 kb Region Conserving Synteny with 800 kb of Human Chromosome 7
- Heather Davidson,
- Martin S. Taylor,
- Ann Doherty,
- A. Christopher Boyd,
- and David J. Porteous
Genome Res. August 1, 2000 10: 1194-1203; doi:10.1101/gr.10.8.1194

METHODS

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Predicting Protein Function by Genomic Context: Quantitative Evaluation and Qualitative Inferences
- Martijn Huynen,
- Berend Snel,
- Warren Lathe III,
- and Peer Bork
Genome Res. August 1, 2000 10: 1204-1210; doi:10.1101/gr.10.8.1204
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Loss of Heterozygosity Assay for Molecular Detection of Cancer Using Energy-transfer Primers and Capillary Array Electrophoresis
- Igor L. Medintz,
- Chyi-Chia Richard Lee,
- Wendy W. Wong,
- Kristin Pirkola,
- David Sidransky,
- and Richard A. Mathies
Genome Res. August 1, 2000 10: 1211-1218; doi:10.1101/gr.10.8.1211
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High-resolution Quantification of Specific mRNA Levels in Human Brain Autopsies and Biopsies
- Anja Castensson,
- Lina Emilsson,
- Paul Preece,
- and and Elena Jazin
Genome Res. August 1, 2000 10: 1219-1229; doi:10.1101/gr.10.8.1219
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Tissue Gene Expression Analysis Using Arrayed Normalized cDNA Libraries
- Holger Eickhoff,
- Johannes Schuchhardt,
- Igor Ivanov,
- Sebastian Meier-Ewert,
- John O'Brien,
- Arif Malik,
- Neeraj Tandon,
- Eryk-Witold Wolski,
- Elke Rohlfs,
- Lajos Nyarsik,
- Richard Reinhardt,
- Wilfried Nietfeld,
- and Hans Lehrach
Genome Res. August 1, 2000 10: 1230-1240; doi:10.1101/gr.10.8.1230
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A Quantitative Evaluation of SAGE
- Jes Stollberg,
- Johann Urschitz,
- Zsolt Urban,
- and Charles D. Boyd
Genome Res. August 1, 2000 10: 1241-1248; doi:10.1101/gr.10.8.1241
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Determination of Single-Nucleotide Polymorphisms by Real-time Pyrophosphate DNA Sequencing
- Anders Alderborn,
- Anna Kristofferson,
- and Ulf Hammerling
Genome Res. August 1, 2000 10: 1249-1258; doi:10.1101/gr.10.8.1249

RESOURCE

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Expression-based Genetic/Physical Maps of Single-Nucleotide Polymorphisms Identified by the Cancer Genome Anatomy Project
- Robert Clifford,
- Michael Edmonson,
- Ying Hu,
- Cu Nguyen,
- Titia Scherpbier,
- and Kenneth H. Buetow
Genome Res. August 1, 2000 10: 1259-1265; doi:10.1101/gr.10.8.1259

INSIGHT/OUTLOOK

A Chimpanzee Genome Project Is a Biomedical Imperative

WABA Success: A Tool for Sequence Comparison between Large Genomes

Guilt by Association: Contextual Information in Genome Analysis

REVIEW

Automation for Genomics, Part One: Preparation for Sequencing

REPORTS

Genomic Sequence Analysis of the Mouse Naip Gene Array

Gene Survey of the Pathogenic Protozoan Trypanosoma cruzi

GT Repeats Are Associated with Recombination on Human Chromosome 22

ARTICLES

Conservation, Regulation, Synteny, and Introns in a Large-scale C. briggsae–C. elegans Genomic Alignment

Genome-wide Detection of Allelic Imbalance Using Human SNPs and High-density DNA Arrays

LETTERS

Discovery of a Novel, Paternally Expressed Ubiquitin-specific Processing Protease Gene through Comparative Analysis of an Imprinted Region of Mouse Chromosome 7 and Human Chromosome 19q13.4

Alfresco—A Workbench for Comparative Genomic Sequence Analysis

High-resolution Genetic and Physical Map of the Lgn1 Interval in C57BL/6J Implicates Naip2 or Naip5 in Legionella pneumophila Pathogenesis

Eukaryote-specific Domains in Translation Initiation Factors: Implications for Translation Regulation and Evolution of the Translation System

Ecologic Genomics of DNA: Upstream Bending in Prokaryotic Promoters

Genomic Sequence Analysis of Fugu rubripes CFTR and Flanking Genes in a 60 kb Region Conserving Synteny with 800 kb of Human Chromosome 7

METHODS

Predicting Protein Function by Genomic Context: Quantitative Evaluation and Qualitative Inferences

Loss of Heterozygosity Assay for Molecular Detection of Cancer Using Energy-transfer Primers and Capillary Array Electrophoresis

High-resolution Quantification of Specific mRNA Levels in Human Brain Autopsies and Biopsies

Tissue Gene Expression Analysis Using Arrayed Normalized cDNA Libraries

A Quantitative Evaluation of SAGE

Determination of Single-Nucleotide Polymorphisms by Real-time Pyrophosphate DNA Sequencing

RESOURCE

Expression-based Genetic/Physical Maps of Single-Nucleotide Polymorphisms Identified by the Cancer Genome Anatomy Project

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