Volume 30, Issue 1 | January 2020

Research
- - Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation
    Amanda J. Price
    Taeyoung Hwang
    Ran Tao
    Emily E. Burke
    Anandita Rajpurohit
    Joo Heon Shin
    ...[+1 authors]...,
    Thomas M. Hyde
    Joel E. Kleinman
    Andrew E. Jaffe
    Daniel R. Weinberger
    First Published December 18, 2019
  - Asymmetric repair of UV damage in nucleosomes imposes a DNA strand polarity on somatic mutations in skin cancer
    Peng Mao
    Michael J. Smerdon
    Steven A. Roberts
    John J. Wyrick
    First Published December 23, 2019
  - A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis
    Pengfei Cai
    Auke B.C. Otten
    Binbin Cheng
    Mitsuhiro A. Ishii
    Wen Zhang
    First Published December 4, 2019
  - Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification
    Megan Rothstein
    Marcos Simoes-Costa
    First Published December 17, 2019
Methods
- - Copolymerization of single-cell nucleic acids into balls of acrylamide gel
    Siran Li
    Jude Kendall
    Sarah Park
    Zihua Wang
    Joan Alexander
    Andrea Moffitt Nissim Ranade Cassidy Danyko Bruno Gegenhuber Stephan Fischer Brian D. Robinson Herbert Lepor Jessica Tollkuhn Jesse Gillis
    ...[+9 authors]...,
    Eric Brouzes
    Alex Krasnitz
    Dan Levy
    Michael Wigler
    First Published November 14, 2019
  - Identification of pathogenic variant enriched regions across genes and gene families
    Eduardo Pérez-Palma
    Patrick May
    Sumaiya Iqbal
    Lisa-Marie Niestroj
    Juanjiangmeng Du
    Henrike O. Heyne Jessica A. Castrillon Anne O'Donnell-Luria
    ...[+3 authors]...,
    Peter Nürnberg
    Aarno Palotie
    Mark Daly
    Dennis Lal
    First Published December 23, 2019
  - Quantitative prediction of enhancer–promoter interactions
    Polina S. Belokopytova
    Miroslav A. Nuriddinov
    Evgeniy A. Mozheiko
    Daniil Fishman
    Veniamin Fishman
    First Published December 2, 2019
  - Predicting transfer RNA gene activity from sequence and genome context
    Bryan P. Thornlow
    Joel Armstrong
    Andrew D. Holmes
    Jonathan M. Howard
    Russell B. Corbett-Detig
    First Published December 19, 2019
  - CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans
    Ping Wei
    Wen Xue
    Yun Zhao
    Guang Ning
    Jiwu Wang
    First Published November 13, 2019
  - Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9
    Daniel Agudelo
    Sophie Carter
    Minja Velimirovic
    Alexis Duringer
    Jean-François Rivest
    Sébastien Levesque Jeremy Loehr Mathilde Mouchiroud Denis Cyr Paula J. Waters
    ...[+5 authors]...,
    Mathieu Laplante
    Sylvain Moineau
    Adeline Goulet
    Yannick Doyon
    First Published January 3, 2020
Resources
- - Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9
    Yonghua Sun
    Bo Zhang
    Lingfei Luo
    De-Li Shi
    Han Wang
    Zongbin Cui Honghui Huang Ying Cao Xiaodong Shu Wenqing Zhang Jianfeng Zhou Yun Li Jiulin Du Qingshun Zhao Jun Chen Hanbing Zhong Tao P. Zhong Li Li Jing-Wei Xiong Jinrong Peng Wuhan Xiao Jian Zhang Jihua Yao Zhan Yin Xianming Mo Gang Peng Jun Zhu Yan Chen Yong Zhou Dong Liu Weijun Pan Yiyue Zhang Hua Ruan Feng Liu Zuoyan Zhu Anming Meng The ZAKOC Consortium Yonghua Sun Luyuan Pan Houpeng Wang Weixun Xie Mudan He Ding Ye Kuoyu Li Feng Xiong Liyue Liu Linglu Li Yun Zhang Bo Zhang Da Liu Zhenchao Cheng Yingying Hu Qian Wu Zhou Luo Yutian Zhang Yingdan Wu Wenyuan Li Lingfei Luo Jianlong Ma Dashuang Mo Pengcheng Cai Jinzi Chen Junhui Sun Yang Zhou Chuan Wu Rui Ni De-Li Shi Ming Shao Yan-Jun Zhang Li-Jun Feng Xiao-Ning Cheng Ji-Tong Li Yan-Yi Xing Yan Zhang Ya-Ping Meng Bei-Bei Yu Han Wang Jian Huang Shuqing Zhang Cheng Ji Yicheng Tan Jingjing Wang Fanmiao Zhang Mingyong Wang Guodong Huang Zhaomin Zhong Wei Zhang Zongbin Cui Yong Long Guili Song Xiaohui Li Xixi Li Kai Chen Jing Ren Junjun Yan Qing Li Honghui Huang Hua Ruan Shicheng Zhu Xuejiao Chen Jingjing Pan Faming Jiang Jiehui Chen Chao Huang Guoping Dong Xiaogui Yi Ying Cao Ruikun Hu Weilai Huang Jiangfang Liu Hong WangXiao Dong Shu Jianhong Xia Shaoyang Zhao Pengtao Wang Xiuhua Wu Wenqing Zhang Yiyue Zhang Mengchang Xu Wei Liu Zhibing Huang Qing Lin Mei Wu Jianfeng Zhou Aibo Sheng Peipei Tang Xiaoxia Gong Wei Mou Congcong Zu Yun Li Ling Lu Yunzhang Liu Xiaozhi Rong Jianyang Chen Jiulin Du Jiwen Bu Xufei Du Tingting Liu Shanye Gu Qingshun Zhao Zhangji Dong Xiaohua Dong Shasha Cao Yunyun Yue Chun Gu Meijing Liu Jun Chen Hongjian Gong Hanbing Zhong Xuanjun Yang Jiahao Chen Qiushi Xu Tao P. Zhong Daqin Jin Peilu She Jianjian Sun Kaa Seng Lai Li Li Yu Zhang Yanyan Shi Fangying Zhao Jing-Wei Xiong Meijun Pang Lu Gao Lei Lei Jinrong Peng Jane Lo Wuhan Xiao Xiaolian Cai Gang Ouyang Jian Zhang Weirui Ma Liyun Miao Jihua Yao Yu Hu Zhan Yin Xianming Mo Xue Li Gang Peng Cuizhen Zhang Fenghua Wang Jun Zhu Ruimeng Yang Hao Yuan Yan Chen Yi Pan Yong Zhou Dong Liu Feng Zhao Weijun Pan Feng Liu Yanyan Ding Yuanyuan Xue Lu Wang Yifan Zhang Dongyuan Ma Xinyan Lu Shuai Gao Jun Xia Zuoyan Zhu Anming Meng Xingfeng Liu Juhui Qiu Bo Gong Luxi Chen Cong Xiong Likun Yao
    ...[+202 authors]...,
    Cencan Xing
    Yixia Wang
    Weimin Shen
    Jiawei Sun
    First Published December 12, 2019
  - Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow–derived stromal stem cells
    Inigo Barrio-Hernandez
    Abbas Jafari
    Kristoffer T.G. Rigbolt
    Philip Hallenborg
    Virginia Sanchez-Quiles
    Ida Skovrind Vyacheslav Akimov
    ...[+2 authors]...,
    Irina Kratchmarova
    Joern Dengjel
    Moustapha Kassem
    Blagoy Blagoev
    First Published December 12, 2019
  - The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny, and Escherichia core genomic diversity
    Zhemin Zhou
    Nabil-Fareed Alikhan
    Khaled Mohamed
    Yulei Fan
    Mark Achtman
    Derek Brown Marie Chattaway Tim Dallman Richard Delahay Christian Kornschober Ariane Pietzka Burkhard Malorny Liljana Petrovska Rob Davies Andy Robertson
    ...[+10 authors]...,
    William Tyne
    François-Xavier Weill
    Marie Accou-Demartin
    Nicola Williams
    First Published December 6, 2019
Corrigenda
- - Corrigendum: Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging
    Jacob C. Kimmel
    Lolita Penland
    Nimrod D. Rubinstein
    David G. Hendrickson
    David R. Kelley
    First Published January 9, 2020
  - Corrigendum: Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development
    Michal Pawlak
    Katarzyna Z. Kedzierska
    Maciej Migdal
    Karim Abu Nahia
    Jordan A. Ramilowski
    Lukasz Bugajski Kosuke Hashimoto
    ...[+2 authors]...,
    Aleksandra Marconi
    Katarzyna Piwocka
    Piero Carninci
    Cecilia L. Winata
    First Published January 9, 2020

Table of Contents

Volume 30, Issue 1 | January 2020

Research

Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation

Asymmetric repair of UV damage in nucleosomes imposes a DNA strand polarity on somatic mutations in skin cancer

A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis

Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification

Methods

Copolymerization of single-cell nucleic acids into balls of acrylamide gel

Identification of pathogenic variant enriched regions across genes and gene families

Quantitative prediction of enhancer–promoter interactions

Predicting transfer RNA gene activity from sequence and genome context

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9

Resources

Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9

Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow–derived stromal stem cells

The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny, and Escherichia core genomic diversity

Corrigenda

Corrigendum: Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging

Corrigendum: Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development

Table of Contents

Volume 30, Issue 1 | January 2020

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Research

Methods

Resources

Corrigenda