Cover image
Noncoding RNAs in the human genome are depicted as an abundance of stars in a winter's night sky. In this issue, a CRISPR interference (CRISPRi) screen is used to identify a novel long noncoding RNA (lncRNA) that regulates keratinocyte proliferation, cell cycle progression, and clonogenicity in human skin. This lncRNA, named progenitor renewal associated non-coding RNA (PRANCR), is illustrated as one of Santa's reindeer among the stars. (Cover artwork by Bryan Sun. [For details, see Cai et al., pp. 22–34.])
