Volume 26, Issue 5 | May 2016

Research
- - Zygotes segregate entire parental genomes in distinct blastomere lineages causing cleavage-stage chimerism and mixoploidy
    Aspasia Destouni
    Masoud Zamani Esteki
    Maaike Catteeuw
    Olga Tšuiko
    Eftychia Dimitriadou
    Katrien Smits Ants Kurg
    ...[+2 authors]...,
    Andres Salumets
    Ann Van Soom
    Thierry Voet
    Joris R. Vermeesch
    First Published April 12, 2016
  - Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity
    Yishay Pinto
    Orshay Gabay
    Leonardo Arbiza
    Aaron J. Sams
    Alon Keinan
    First Published April 7, 2016
  - Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4
    Kate Liddiard
    Brian Ruis
    Taylor Takasugi
    Adam Harvey
    Kevin E. Ashelford
    First Published March 3, 2016
  - Enhancer methylation dynamics contribute to cancer plasticity and patient mortality
    Rachel E. Bell
    Tamar Golan
    Danna Sheinboim
    Hagar Malcov
    David Amar
    Avi Salamon Tamar Liron
    ...[+2 authors]...,
    Sahar Gelfman
    Yankel Gabet
    Ron Shamir
    Carmit Levy
    First Published February 23, 2016
  - Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters
    Vibhor Kumar
    Nirmala Arul Rayan
    Masafumi Muratani
    Stefan Lim
    Bavani Elanggovan
    Lixia Xin Tess Lu Harshyaa Makhija
    ...[+3 authors]...,
    Jeremie Poschmann
    Thomas Lufkin
    Huck Hui Ng
    Shyam Prabhakar
    First Published March 8, 2016
  - Human MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest
    Andrea Orioli
    Viviane Praz
    Philippe Lhôte
    Nouria Hernandez
    First Published March 3, 2016
  - nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
    Valentina Gandin
    Laia Masvidal
    Laura Hulea
    Simon-Pierre Gravel
    Marie Cargnello
    Shannon McLaughlan Yutian Cai Preetika Balanathan Masahiro Morita Arjuna Rajakumar Luc Furic Michael Pollak John A. Porco
    ...[+8 authors]...,
    Julie St-Pierre
    Jerry Pelletier
    Ola Larsson
    Ivan Topisirovic
    First Published March 16, 2016
  - Discovery of a new repeat family in the Callithrix jacchus genome
    Miriam K. Konkel
    Brygg Ullmer
    Erika L. Arceneaux
    Sreeja Sanampudi
    Sarah A. Brantley
    First Published February 25, 2016
Methods
- - Integrative subcellular proteomic analysis allows accurate prediction of human disease-causing genes
    Li Zhao
    Yiyun Chen
    Amol Onkar Bajaj
    Aiden Eblimit
    Mingchu Xu
    Zachry T. Soens Feng Wang Zhongqi Ge Sung Yun Jung Feng He
    ...[+5 authors]...,
    Yumei Li
    Theodore G. Wensel
    Jun Qin
    Rui Chen
    First Published February 24, 2016
  - An extended set of yeast-based functional assays accurately identifies human disease mutations
    Song Sun
    Fan Yang
    Guihong Tan
    Michael Costanzo
    Rose Oughtred
    Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
    ...[+10 authors]...,
    Brenda J. Andrews
    Charles Boone
    Kara Dolinski
    Frederick P. Roth
    First Published March 14, 2016
  - 2C-Cas9: a versatile tool for clonal analysis of gene function
    Vincenzo Di Donato
    Flavia De Santis
    Thomas O. Auer
    Noé Testa
    Héctor Sánchez-Iranzo
    First Published March 8, 2016
  - Sequence-targeted nucleosome sliding in vivo by a hybrid Chd1 chromatin remodeler
    Jeffrey N. McKnight
    Toshio Tsukiyama
    Gregory D. Bowman
    First Published March 18, 2016
Resource
- - Improved definition of the mouse transcriptome via targeted RNA sequencing
    Giovanni Bussotti
    Tommaso Leonardi
    Michael B. Clark
    Tim R. Mercer
    Joanna Crawford
    Lorenzo Malquori
    ...[+1 authors]...,
    Cedric Notredame
    Marcel E. Dinger
    John S. Mattick
    Anton J. Enright
    First Published May 2, 2016
Corrigenda
- - Corrigendum: Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies
    PingHsun Hsieh
    August E. Woerner
    Jeffrey D. Wall
    Joseph Lachance
    Sarah A. Tishkoff
    First Published May 2, 2016
  - Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
    Young Seok Ju
    Jose M.C. Tubio
    William Mifsud
    Beiyuan Fu
    Helen R. Davies
    Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
    ...[+39 authors]...,
    Fengtang Yang
    Serena Nik-Zainal
    Peter J. Campbell
    Michael R. Stratton
    First Published May 2, 2016

Table of Contents

Volume 26, Issue 5 | May 2016

Research

Zygotes segregate entire parental genomes in distinct blastomere lineages causing cleavage-stage chimerism and mixoploidy

Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity

Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4

Enhancer methylation dynamics contribute to cancer plasticity and patient mortality

Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters

Human MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest

nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

Discovery of a new repeat family in the Callithrix jacchus genome

Methods

Integrative subcellular proteomic analysis allows accurate prediction of human disease-causing genes

An extended set of yeast-based functional assays accurately identifies human disease mutations

2C-Cas9: a versatile tool for clonal analysis of gene function

Sequence-targeted nucleosome sliding in vivo by a hybrid Chd1 chromatin remodeler

Resource

Improved definition of the mouse transcriptome via targeted RNA sequencing

Corrigenda

Corrigendum: Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Table of Contents

Volume 26, Issue 5 | May 2016

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Research

Methods

Resource

Corrigenda