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Method

Fast and accurate mapping of long reads to complete genome assemblies with VerityMap

  • First Published November 15, 2022
Research

Caenorhabditis nematode" > Genetic exchange with an outcrossing sister species causes severe genome-wide dysregulation in a selfing Caenorhabditis nematode

  • First Published November 9, 2022
Method

Sequencing Illumina libraries at high accuracy on the ONT MinION using R2C2

  • First Published November 9, 2022
Research

Caenorhabditis elegans" > Systematic transcriptome analysis associated with physiological and chronological aging in Caenorhabditis elegans

  • First Published November 9, 2022
Research

Non-Mendelian inheritance patterns and extreme deviation rates of CGG repeats in autism

  • First Published November 9, 2022
Research

Hybridization drives mitochondrial DNA degeneration and metabolic shift in a species with biparental mitochondrial inheritance

  • First Published November 9, 2022
Method

Methyl-SNP-seq reveals dual readouts of methylome and variome at molecule resolution while enabling target enrichment

  • First Published November 4, 2022
Corrigendum

Corrigendum: Cell cycle arrest explains the observed bulk 3D genomic alterations in response to long-term heat shock in K562 cells

  • First Published November 2, 2022
Method

Direct detection of natural selection in Bronze Age Britain

  • First Published October 31, 2022
Research

Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels

  • First Published October 13, 2022
Method

A statistical physics approach for disease module detection

  • First Published October 11, 2022
Method

A model-based constrained deep learning clustering approach for spatially resolved single-cell data

  • First Published October 5, 2022
Research

C. elegans short tandem repeats" > Natural variation in C. elegans short tandem repeats

  • First Published October 4, 2022
Research

Functional characterization of enhancer activity during a long terminal repeat's evolution

  • First Published October 3, 2022
Method

Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells

  • First Published September 30, 2022
Research

Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis

  • First Published September 30, 2022
Resource

A high-resolution map of small-scale inversions in the gibbon genome

  • First Published September 30, 2022
RECOMB 2022 Special/Methods

Learning probabilistic protein–DNA recognition codes from DNA-binding specificities using structural mappings

  • First Published September 19, 2022
Research

A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility

  • First Published September 15, 2022
Research

Widespread association of the Argonaute protein AGO2 with meiotic chromatin suggests a distinct nuclear function in mammalian male reproduction

  • First Published September 15, 2022
Resource

The western redcedar genome reveals low genetic diversity in a self-compatible conifer

  • First Published September 15, 2022
Research

Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection–related chromatin reorganization" > Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection–related chromatin reorganization

  • First Published September 15, 2022
Research

Identification of a transcriptional signature found in multiple models of ASD and related disorders

  • First Published September 14, 2022
Method

Surveying mutation density patterns around specific genomic features

  • First Published September 13, 2022
Method

Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling

  • First Published September 13, 2022
Method

Scalable and model-free detection of spatial patterns and colocalization

  • First Published September 9, 2022
Research

Mosaic loss of Chromosome Y in aged human microglia

  • First Published August 30, 2022
Corrigendum

Corrigendum: Human primitive brain displays negative mitochondrial-nuclear expression correlation of respiratory genes

  • First Published August 25, 2022
Resource

Assembly of a pangenome for global cattle reveals missing sequences and novel structural variations, providing new insights into their diversity and evolutionary history

  • First Published August 17, 2022
Resource

dbEmbryo multi-omics database for analyses of synergistic regulation in early mammalian embryo development

  • First Published August 17, 2022
Research

An atlas of fish genome evolution reveals delayed rediploidization following the teleost whole-genome duplication

  • First Published August 12, 2022
Method

Deep sequencing of short capped RNAs reveals novel families of noncoding RNAs

  • First Published August 12, 2022
Research

ceRNA crosstalk mediated by ncRNAs is a novel regulatory mechanism in fish sex determination and differentiation

  • First Published August 12, 2022
Resource

Recent, full-length gene retrocopies are common in canids

  • First Published August 12, 2022
Research

Genomic analyses of wild argali, domestic sheep, and their hybrids provide insights into chromosome evolution, phenotypic variation, and germplasm innovation

  • First Published August 10, 2022
Research

Ruminant-specific retrotransposons shape regulatory evolution of bovine immunity

  • First Published August 10, 2022
Research

Single-cell multi-omics of human preimplantation embryos shows susceptibility to glucocorticoids

  • First Published August 10, 2022
RECOMB 2022 Special/Methods

Assembler artifacts include misassembly because of unsafe unitigs and underassembly because of bidirected graphs

  • First Published July 27, 2022
Research

Coordination of zygotic genome activation entry and exit by H3K4me3 and H3K27me3 in porcine early embryos

  • First Published July 22, 2022
Method

High-resolution simulations of chromatin folding at genomic rearrangements in malignant B cells provide mechanistic insights into proto-oncogene deregulation

  • First Published July 21, 2022
Method

Identifying cell state–associated alternative splicing events and their coregulation

  • First Published July 20, 2022
Method

TransMeta simultaneously assembles multisample RNA-seq reads

  • First Published July 20, 2022
Research

Compartment-specific and ELAVL1-coordinated regulation of intronic polyadenylation isoforms by doxorubicin

  • First Published July 20, 2022
Perspective

Diversifying the genomic data science research community

  • First Published July 20, 2022
Research

Transcriptome innovations in primates revealed by single-molecule long-read sequencing

  • First Published July 15, 2022
Research

Cell cycle arrest explains the observed bulk 3D genomic alterations in response to long-term heat shock in K562 cells

  • First Published July 14, 2022
Method

Haplotype and population structure inference using neural networks in whole-genome sequencing data

  • First Published July 6, 2022
Method

Highly accurate quantification of allelic gene expression for population and disease genetics

  • First Published July 6, 2022
Method

An efficient method to identify, date, and describe admixture events using haplotype information

  • First Published July 6, 2022
RECOMB 2022 Special/Methods

Unsupervised cell functional annotation for single-cell RNA-seq

  • First Published June 28, 2022
Research

High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes

  • First Published June 27, 2022
Resource

KCNQ4" > Proactive functional classification of all possible missense single-nucleotide variants in KCNQ4

  • First Published June 27, 2022
Corrigendum

Corrigendum: Enhancer–silencer transitions in the human genome

  • First Published June 24, 2022
Corrigendum

Corrigendum: NicE-C efficiently reveals open chromatin–associated chromosome interactions at high resolution

  • First Published June 24, 2022
Corrigendum

Corrigendum: An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease–related patterns

  • First Published June 24, 2022
RECOMB 2022 Special/Methods

Ultra-high-diversity factorizable libraries for efficient therapeutic discovery

  • First Published June 23, 2022
Research

Genomic analysis of Rad26 and Rad1–Rad10 reveals differences in their dependence on Mediator and RNA polymerase II

  • First Published June 23, 2022
Research

Somatic retrotransposition in the developing rhesus macaque brain

  • First Published June 21, 2022
Research

HDAC9 structural variants disrupting TWIST1 transcriptional regulation lead to craniofacial and limb malformations" > HDAC9 structural variants disrupting TWIST1 transcriptional regulation lead to craniofacial and limb malformations

  • First Published June 16, 2022
Method

Dynamic regulatory module networks for inference of cell type–specific transcriptional networks

  • First Published June 15, 2022
Research

Extensive protein dosage compensation in aneuploid human cancers

  • First Published June 14, 2022
Method

Polishing copy number variant calls on exome sequencing data via deep learning

  • First Published June 13, 2022
Research

Diurnal and eating-associated microbial patterns revealed via high-frequency saliva sampling

  • First Published June 10, 2022
Resource

Precision environmental health monitoring by longitudinal exposome and multi-omics profiling

  • First Published June 6, 2022
Research

Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways

  • First Published June 1, 2022
Research

Frequent somatic gene conversion as a mechanism for loss of heterozygosity in tumor suppressor genes

  • First Published May 26, 2022
Research

Evolution of transcription factor binding through sequence variations and turnover of binding sites

  • First Published May 26, 2022
Resource

Native RNA sequencing in fission yeast reveals frequent alternative splicing isoforms

  • First Published May 26, 2022
Method

Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data

  • First Published May 24, 2022
Research

TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation

  • First Published May 24, 2022
RECOMB 2022 Special/Methods

Lossless indexing with counting de Bruijn graphs

  • First Published May 24, 2022
Research

Rtt109 promotes nucleosome replacement ahead of the replication fork

  • First Published May 24, 2022
Corrigendum

Corrigendum: Low-input RNase footprinting for simultaneous quantification of cytosolic and mitochondrial translation

  • First Published May 11, 2022
Method

Automated annotation of human centromeres with HORmon

  • First Published May 11, 2022
Research

Rapid evolution and strain turnover in the infant gut microbiome

  • First Published May 11, 2022
Method

Gene prediction in the immunoglobulin loci

  • First Published May 11, 2022
Method

Early embryonic mutations reveal dynamics of somatic and germ cell lineages in mice

  • First Published May 9, 2022
Research

Drosophila" > Transposable element accumulation drives size differences among polymorphic Y Chromosomes in Drosophila

  • First Published May 2, 2022
Research

Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression

  • First Published May 2, 2022
Research

E. coli measured at single-base resolution" > Genome-wide promoter assembly in E. coli measured at single-base resolution

  • First Published April 28, 2022
Method

A complete pedigree-based graph workflow for rare candidate variant analysis

  • First Published April 28, 2022
Research

Relative contributions of sex hormones, sex chromosomes, and gonads to sex differences in tissue gene regulation

  • First Published April 8, 2022
Research

Long-read sequencing of 111 rice genomes reveals significantly larger pan-genomes

  • First Published April 8, 2022
Research

H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells

  • First Published April 8, 2022
Method

Chromatin interaction–aware gene regulatory modeling with graph attention networks

  • First Published April 8, 2022
Method

Variations in antibody repertoires correlate with vaccine responses

  • First Published March 31, 2022
Research

Saccharomyces cerevisiae in Taiwan reveals ecology and evolution of predomesticated lineages" > Extensive sampling of Saccharomyces cerevisiae in Taiwan reveals ecology and evolution of predomesticated lineages

  • First Published March 31, 2022
Perspective

Short arms of human acrocentric chromosomes and the completion of the human genome sequence

  • First Published March 31, 2022
Commentary

Implications of the first complete human genome assembly

  • First Published March 31, 2022
Perspective

The genetics and epigenetics of satellite centromeres

  • First Published March 31, 2022
Research

The role of insulators and transcription in 3D chromatin organization of flies

  • First Published March 30, 2022
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