Your search for returned 6,370 results
Method
Genome skimming with nanopore sequencing precisely determines global and transposon DNA methylation in vertebrates
- First Published July 13, 2023
Research
Poecilia reticulata" > Extensive variation in germline de novo mutations in Poecilia reticulata
- First Published July 13, 2023
Research
Drosophila melanogaster" > Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster
- First Published July 13, 2023
Method
Accurate sequencing of DNA motifs able to form alternative (non-B) structures
- First Published July 11, 2023
Method
Genomic sketching with multiplicities and locality-sensitive hashing using Dashing 2
- First Published July 6, 2023
Method
Leveraging protein language models for accurate multiple sequence alignments
- First Published July 6, 2023
Method
Efficient mapping of accurate long reads in minimizer space with mapquik
- First Published June 30, 2023
Method
Fast inference of genetic recombination rates in biobank scale data
- First Published June 22, 2023
Method
Modeling and predicting cancer clonal evolution with reinforcement learning
- First Published June 21, 2023
Method
Deriving confidence intervals for mutation rates across a wide range of evolutionary distances using FracMinHash
- First Published June 21, 2023
Corrigendum
Neurospora crassa" > Corrigendum: Chromatin structure influences rate and spectrum of spontaneous mutations in Neurospora crassa
- First Published June 16, 2023
Method
Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models
- First Published June 14, 2023
Method
Minimal positional substring cover is a haplotype threading alternative to Li and Stephens model
- First Published June 14, 2023
Resource
The fine-scale recombination rate variation and associations with genomic features in a butterfly
- First Published June 12, 2023
Method
Accurate integration of multiple heterogeneous single-cell RNA-seq data sets by learning contrastive biological variation
- First Published June 12, 2023
Method
Characterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets
- First Published June 12, 2023
Method
Debiased personalized gene coexpression networks for population-scale scRNA-seq data
- First Published June 9, 2023
Research
Integration site–dependent HIV-1 promoter activity shapes host chromatin conformation
- First Published June 9, 2023
Method
Targeted, programmable, and precise tandem duplication in the mammalian genome
- First Published June 9, 2023
Resource
Brassica napus using a pooled CRISPR library" > Genome-scale targeted mutagenesis in Brassica napus using a pooled CRISPR library
- First Published June 8, 2023
Research
Plant polymerase IV sensitizes chromatin through histone modifications to preclude spread of silencing into protein-coding domains
- First Published June 5, 2023
Method
Genealogical inference and more flexible sequence clustering using iterative-PopPUNK
- First Published May 30, 2023
Method
Extremely fast construction and querying of compacted and colored de Bruijn graphs with GGCAT
- First Published May 30, 2023
Resource
Discordant calls across genotype discovery approaches elucidate variants with systematic errors
- First Published May 30, 2023
Method
A fast and scalable method for inferring phylogenetic networks from trees by aligning lineage taxon strings
- First Published May 22, 2023
Research
Variation in histone configurations correlates with gene expression across nine inbred strains of mice
- First Published May 22, 2023
Method
Enabling tradeoffs in privacy and utility in genomic data Beacons and summary statistics
- First Published May 22, 2023
Method
Leveraging family data to design Mendelian randomization that is provably robust to population stratification
- First Published May 17, 2023
Method
Improving quartet graph construction for scalable and accurate species tree estimation from gene trees
- First Published May 17, 2023
Method
Efficient and accurate KIR and HLA genotyping with massively parallel sequencing data
- First Published May 11, 2023
Research
Gaps and complex structurally variant loci in phased genome assemblies
- First Published May 10, 2023
Resource
Comparing genomic and epigenomic features across species using the WashU Comparative Epigenome Browser
- First Published May 8, 2023
Research
Dynamic modulation of genomic enhancer elements in the suprachiasmatic nucleus, the site of the mammalian circadian clock
- First Published May 8, 2023
Method
Multiplexed long-read plasmid validation and analysis using OnRamp
- First Published May 8, 2023
Perspective
Challenges and considerations for reproducibility of STARR-seq assays
- First Published May 2, 2023
Method
CRISPR-Cas9-based repeat depletion for high-throughput genotyping of complex plant genomes
- First Published May 1, 2023
Research
Highly complete long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity
- First Published May 1, 2023
Method
Accurate transcriptome-wide identification and quantification of alternative polyadenylation from RNA-seq data with APAIQ
- First Published April 28, 2023
Research
Incomplete erasure of histone marks during epigenetic reprogramming in medaka early development
- First Published April 28, 2023
Research
MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain
- First Published April 26, 2023
Resource
A single-cell transcriptome atlas of the maturing zebrafish telencephalon
- First Published April 18, 2023
Method
Density separation of petrous bone powders for optimized ancient DNA yields
- First Published April 18, 2023
Research
Motif conservation, stability, and host gene expression are the main drivers of snoRNA expression across vertebrates
- First Published April 18, 2023
Method
Genome enrichment of rare and unknown species from complicated microbiomes by nanopore selective sequencing
- First Published April 11, 2023
Research
The motif composition of variable number tandem repeats impacts gene expression
- First Published April 10, 2023
Resource
A sheep pangenome reveals the spectrum of structural variations and their effects on tail phenotypes
- First Published April 3, 2023
Resource
Genome-wide identification of tandem repeats associated with splicing variation across 49 tissues in humans
- First Published March 27, 2023
Method
Simultaneous profiling of host expression and microbial abundance by spatial metatranscriptome sequencing
- First Published March 27, 2023
Research
SWATH-MS-based proteogenomic analysis reveals the involvement of alternative splicing in poplar upon lead stress
- First Published March 24, 2023
Method
Tn5 tagments and transposes oligos to single-stranded DNA for strand-specific RNA sequencing
- First Published March 23, 2023
Research
Enhancers display constrained sequence flexibility and context-specific modulation of motif function
- First Published March 20, 2023
Research
The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters
- First Published March 16, 2023
Research
Neurospora crassa" > Chromatin structure influences rate and spectrum of spontaneous mutations in Neurospora crassa
- First Published March 15, 2023
Method
Defining the separation landscape of topological domains for decoding consensus domain organization of the 3D genome
- First Published March 9, 2023
Resource
Complete sequencing of a cynomolgus macaque major histocompatibility complex haplotype
- First Published February 28, 2023
Research
Large haplotypes highlight a complex age structure within the maize pan-genome
- First Published February 28, 2023
Method
Complex hierarchical structures in single-cell genomics data unveiled by deep hyperbolic manifold learning
- First Published February 27, 2023
Method
Characterization of network hierarchy reflects cell state specificity in genome organization
- First Published February 24, 2023
Resource
The Planemo toolkit for developing, deploying, and executing scientific data analyses in Galaxy and beyond
- First Published February 24, 2023
Research
DNMT3B-mutated ICF1 patient iPSCs is amenable to correction, with the exception of a subset of regions with H3K4me3- and/or CTCF-based epigenetic memory" > The aberrant epigenome of DNMT3B-mutated ICF1 patient iPSCs is amenable to correction, with the exception of a subset of regions with H3K4me3- and/or CTCF-based epigenetic memory
- First Published February 24, 2023
Research
Kinetic networks identify TWIST2 as a key regulatory node in adipogenesis
- First Published February 21, 2023
Research
Regulation of endogenous retrovirus–derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells
- First Published February 17, 2023
Method
Atlas-scale single-cell chromatin accessibility using nanowell-based combinatorial indexing
- First Published February 15, 2023
Method
N6-methyldeoxyadenosine antibody-based genomic profiling in eukaryotes" > Evaluation of N6-methyldeoxyadenosine antibody-based genomic profiling in eukaryotes
- First Published February 14, 2023
Research
Multi-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptional repression during oogenesis
- First Published January 23, 2023
Method
Robust analysis of prokaryotic pangenome gene gain and loss rates with Panstripe
- First Published January 20, 2023
Method
An efficient genotyper and star-allele caller for pharmacogenomics
- First Published January 19, 2023
Method
Nematode gene annotation by machine-learning-assisted proteotranscriptomics enables proteome-wide evolutionary analysis
- First Published January 18, 2023
Method
Matching queried single-cell open-chromatin profiles to large pools of single-cell transcriptomes and epigenomes for reference supported analysis
- First Published January 18, 2023
Resource
A temporal in vivo catalog of chromatin accessibility and expression profiles in pineoblastoma reveals a prevalent role for repressor elements
- First Published January 17, 2023
Research
Active enhancers strengthen insulation by RNA-mediated CTCF binding at chromatin domain boundaries
- First Published January 17, 2023
Resource
Hydra genome reveals conserved regulators of cell state" > A chromosome-scale epigenetic map of the Hydra genome reveals conserved regulators of cell state
- First Published January 13, 2023
Resource
Dynamic regulation of gonadal transposon control across the lifespan of the naturally short-lived African turquoise killifish
- First Published December 28, 2022
Research
Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation
- First Published December 28, 2022
Erratum
Erratum: A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility
- First Published December 22, 2022
Method
A somatic hypermutation–based machine learning model stratifies individuals with Crohn's disease and controls
- First Published December 16, 2022
Method
Cross-species cell-type assignment from single-cell RNA-seq data by a heterogeneous graph neural network
- First Published December 16, 2022
Research
Redistribution of lamina-associated domains reshapes binding of pioneer factor FOXA2 in development of nonalcoholic fatty liver disease
- First Published December 15, 2022
Method
Three assays for in-solution enrichment of ancient human DNA at more than a million SNPs
- First Published December 14, 2022
Research
Chlamydomonas reinhardtii" > Rates and spectra of de novo structural mutations in Chlamydomonas reinhardtii
- First Published December 12, 2022
Research
Diversity, duplication, and genomic organization of homeobox genes in Lepidoptera
- First Published December 8, 2022
Method
Estimation of intrafamilial DNA contamination in family trio genome sequencing using deviation from Mendelian inheritance
- First Published December 6, 2022
Research
Gene essentiality in cancer cell lines is modified by the sex chromosomes
- First Published November 23, 2022
Method
Analyzing rare mutations in metagenomes assembled using long and accurate reads
- First Published November 23, 2022
Method
Marker-free characterization of full-length transcriptomes of single live circulating tumor cells
- First Published November 22, 2022