Your search for returned 6,370 results
Resource
Haplotype-resolved 3D chromatin architecture of the hybrid pig
- First Published March 13, 2024
Research
N6-adenine methylation (6mA) governs the encystment process, showcased in the unicellular eukaryote Pseudocohnilembus persalinus" > Dynamic DNA N6-adenine methylation (6mA) governs the encystment process, showcased in the unicellular eukaryote Pseudocohnilembus persalinus
- First Published March 12, 2024
Research
RNA Pol II–dependent transcription efficiency fine-tunes A-to-I editing levels
- First Published March 12, 2024
Resource
Comprehensive assessment of 11 de novo HiFi assemblers on complex eukaryotic genomes and metagenomes
- First Published March 1, 2024
Research
Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma
- First Published February 26, 2024
Resource
Pangenome-genotyped structural variation improves molecular phenotype mapping in cattle
- First Published February 14, 2024
Research
Differences in molecular sampling and data processing explain variation among single-cell and single-nucleus RNA-seq experiments
- First Published February 14, 2024
Research
Preferential formation of Z-RNA over intercalated motifs in long noncoding RNA
- First Published February 14, 2024
Corrigendum
Corrigendum: A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons
- First Published February 7, 2024
Perspective
Why community consultation matters in genomic research benefit-sharing models
- First Published January 31, 2024
Method
A statistical learning method for simultaneous copy number estimation and subclone clustering with single-cell sequencing data
- First Published January 30, 2024
Research
Oxidative stress accelerates intestinal tumorigenesis by enhancing 8-oxoguanine-mediated mutagenesis in MUTYH-deficient mice
- First Published January 30, 2024
Resource
GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis
- First Published January 30, 2024
Research
Histone deacetylases maintain expression of the pluripotent gene network via recruitment of RNA polymerase II to coding and noncoding loci
- First Published January 30, 2024
Method
A Bayesian framework to study tumor subclone–specific expression by combining bulk DNA and single-cell RNA sequencing data
- First Published January 9, 2024
Method
Bombyx mori" > High-throughput and genome-scale targeted mutagenesis using CRISPR in a nonmodel multicellular organism, Bombyx mori
- First Published January 8, 2024
Research
Small polymorphisms are a source of ancestral bias in structural variant breakpoint placement
- First Published January 4, 2024
Method
Power-law behavior of transcriptional bursting regulated by enhancer–promoter communication
- First Published January 3, 2024
Research
Xenopus sperm and male pronuclei" > Cohesin and CTCF do not assemble TADs in Xenopus sperm and male pronuclei
- First Published December 21, 2023
Research
De novo transcriptome assembly of mouse male germ cells reveals novel genes, stage-specific bidirectional promoter activity, and noncoding RNA expression
- First Published December 21, 2023
Method
Data integration and inference of gene regulation using single-cell temporal multimodal data with scTIE
- First Published December 15, 2023
Method
Assessing and mitigating privacy risks of sparse, noisy genotypes by local alignment to haplotype databases
- First Published December 14, 2023
Research
Identification and validation of supervariants reveal novel loci associated with human white matter microstructure
- First Published December 12, 2023
Research
Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase
- First Published December 11, 2023
Method
Using long-read CAGE sequencing to profile cryptic-promoter-derived transcripts and their contribution to the immunopeptidome
- First Published December 8, 2023
Research
Whole-genome long-read sequencing downsampling and its effect on variant-calling precision and recall
- First Published December 7, 2023
Research
Evidence for selfing in a vertebrate from whole-genome sequencing
- First Published December 7, 2023
Method
Aberrant landscapes of maternal meiotic crossovers contribute to aneuploidies in human embryos
- First Published December 1, 2023
Research
Proteome-wide structural analysis quantifies structural conservation across distant species
- First Published November 22, 2023
Method
Integrating SNVs and CNAs on a phylogenetic tree from single-cell DNA sequencing data
- First Published November 22, 2023
Research
Transposon wave remodeled the epigenomic landscape in the rapid evolution of X-Chromosome dosage compensation
- First Published November 21, 2023
Research
MBD4 causes maternal germline hypermutation in primates" > A naturally occurring variant of MBD4 causes maternal germline hypermutation in primates
- First Published November 20, 2023
Method
Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice
- First Published November 17, 2023
Research
Cellular age explains variation in age-related cell-to-cell transcriptome variability
- First Published November 16, 2023
Research
Drosophila metamorphosis" > tRNA-derived small RNAs are embedded in the gene regulatory network instructing Drosophila metamorphosis
- First Published November 16, 2023
Research
A DNA methylation haplotype block landscape in human tissues and preimplantation embryos reveals regulatory elements defined by comethylation patterns
- First Published November 8, 2023
Research
Telomeric repeat evolution in the phylum Nematoda revealed by high-quality genome assemblies and subtelomere structures
- First Published November 2, 2023
Research
TERT promoter" > E4F1 and ZNF148 are transcriptional activators of the −57A > C and wild-type TERT promoter
- First Published November 2, 2023
Method
De novo reconstruction of satellite repeat units from sequence data
- First Published November 2, 2023
Resource
The pig pangenome provides insights into the roles of coding structural variations in genetic diversity and adaptation
- First Published November 1, 2023
Method
Infernape uncovers cell type–specific and spatially resolved alternative polyadenylation in the brain
- First Published October 31, 2023
Resource
Multiscale network modeling reveals the gene regulatory landscape driving cancer prognosis in 32 cancer types
- First Published October 31, 2023
Method
Latent feature extraction with a prior-based self-attention framework for spatial transcriptomics
- First Published October 30, 2023
Research
Clustered and diverse transcription factor binding underlies cell type specificity of enhancers for housekeeping genes
- First Published October 26, 2023
Research
Single-cell transcriptome and metagenome profiling reveals the genetic basis of rumen functions and convergent developmental patterns in ruminants
- First Published October 26, 2023
Research
GC-biased gene conversion drives accelerated evolution of ultraconserved elements in mammalian and avian genomes
- First Published October 26, 2023
Method
Localizing unmapped sequences with families to validate the Telomere-to-Telomere assembly and identify new hotspots for genetic diversity
- First Published October 25, 2023
Method
Identifying crossovers and shared genetic material in whole genome sequencing data from families
- First Published October 25, 2023
Research
Genome-wide chromatin interaction profiling reveals a vital role of super-enhancers and rearrangements in host enhancer contacts during BmNPV infection
- First Published October 23, 2023
Research
Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells
- First Published October 18, 2023
Research
Transposon accumulation at xenobiotic gene family loci in aphids
- First Published October 18, 2023
Method
ESICCC as a systematic computational framework for evaluation, selection, and integration of cell-cell communication inference methods
- First Published October 12, 2023
Research
Deciphering D4Z4 CpG methylation gradients in fascioscapulohumeral muscular dystrophy using nanopore sequencing
- First Published October 5, 2023
Research
Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development
- First Published October 5, 2023
Research
Comprehensive isoform-level analysis reveals the contribution of alternative isoforms to venom evolution and repertoire diversity
- First Published October 5, 2023
Research
Drosophila natural strains" > Transposons contribute to the functional diversification of the head, gut, and ovary transcriptomes across Drosophila natural strains
- First Published October 4, 2023
Research
The rate of de novo structural variation is increased in in vitro–produced offspring and preferentially affects the paternal genome
- First Published October 4, 2023
Resource
An organism-wide ATAC-seq peak catalog for the bovine and its use to identify regulatory variants
- First Published September 26, 2023
Research
Analyses of 600+ insect genomes reveal repetitive element dynamics and highlight biodiversity-scale repeat annotation challenges
- First Published September 22, 2023
Resource
Genetic features and genomic targets of human KRAB-zinc finger proteins
- First Published September 20, 2023
Resource
Single-nucleus transcriptomic mapping uncovers targets for traumatic brain injury
- First Published September 20, 2023
Resource
Acomys) ear" > Spatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse (Acomys) ear
- First Published September 19, 2023
Research
Transposable elements drive the evolution of metazoan zinc finger genes
- First Published September 15, 2023
Research
Bos species" > A Chinese indicine pangenome reveals a wealth of novel structural variants introgressed from other Bos species
- First Published September 15, 2023
Research
Nucleosome repositioning in chronic lymphocytic leukemia
- First Published September 12, 2023
Research
Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features
- First Published September 12, 2023
Research
Copy number variation alters local and global mutational tolerance
- First Published August 31, 2023
Research
Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits
- First Published August 25, 2023
Method
Accurate and fast graph-based pangenome annotation and clustering with ggCaller
- First Published August 24, 2023
Method
Fast and accurate out-of-core PCA framework for large scale biobank data
- First Published August 24, 2023
Research
Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotype organization
- First Published August 17, 2023
Research
Chlamydomonas reinhardtii" > Telomerase-independent survival leads to a mosaic of complex subtelomere rearrangements in Chlamydomonas reinhardtii
- First Published August 14, 2023
Method
Dissecting and improving gene regulatory network inference using single-cell transcriptome data
- First Published August 14, 2023
Method
Ultrafast genome-wide inference of pairwise coalescence times
- First Published August 10, 2023
Method
k using minimum decycling sets" > Efficient minimizer orders for large values of k using minimum decycling sets
- First Published August 9, 2023
Method
Partial alignment of multislice spatially resolved transcriptomics data
- First Published August 8, 2023
Method
Assessing transcriptomic reidentification risks using discriminative sequence models
- First Published August 4, 2023
Research
ZSWIM8 destabilizes many murine microRNAs and is required for proper embryonic growth and development
- First Published August 2, 2023
Method
A transcriptome-based single-cell biological age model and resource for tissue-specific aging measures
- First Published July 31, 2023
Method
Diffusion-enhanced characterization of 3D chromatin structure reveals its linkage to gene regulatory networks and the interactome
- First Published July 25, 2023
Method
Inferring and comparing metabolism across heterogeneous sets of annotated genomes using AuCoMe
- First Published July 19, 2023
Research
Historical RNA expression profiles from the extinct Tasmanian tiger
- First Published July 18, 2023
Research
Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells
- First Published July 18, 2023
Method
Unraveling the palindromic and nonpalindromic motifs of retroviral integration site sequences by statistical mixture models
- First Published July 18, 2023
Research
Ultra-long-range interactions between active regulatory elements
- First Published July 14, 2023
Research
Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution
- First Published July 13, 2023