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Letter

Nucleosomes are well positioned in exons and carry characteristic histone modifications

  • First Published August 17, 2009
Letter

cis-acting sequences" > Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences

  • First Published August 17, 2009
Resource

LookSeq: A browser-based viewer for deep sequencing data

  • First Published August 13, 2009
Letter

Desulfovibrio magneticus strain RS-1 revealed common gene clusters in magnetotactic bacteria" > Whole genome sequence of Desulfovibrio magneticus strain RS-1 revealed common gene clusters in magnetotactic bacteria

  • First Published August 12, 2009
Resource

BayesCall: A model-based base-calling algorithm for high-throughput short-read sequencing

  • First Published August 6, 2009
Methods

Sensitive and accurate detection of copy number variants using read depth of coverage

  • First Published August 5, 2009
Letter

Population genomics in a disease targeted primary cell model

  • First Published August 4, 2009
Methods

Distinguishing direct versus indirect transcription factor–DNA interactions

  • First Published August 3, 2009
Letter

The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands

  • First Published August 3, 2009
Letter

5′-Transducing SVA retrotransposon groups spread efficiently throughout the human genome

  • First Published August 3, 2009
Erratum

Erratum

  • First Published August 3, 2009
Resource

Fast model-based estimation of ancestry in unrelated individuals

  • First Published July 31, 2009
Methods

Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing

  • First Published July 28, 2009
Letter

Exon-trapping mediated by the human retrotransposon SVA

  • First Published July 27, 2009
Letter

Profiling the repertoire of phenotypes influenced by environmental cues that occur during asexual reproduction

  • First Published July 27, 2009
Resource

GenGIS: A geospatial information system for genomic data

  • First Published July 27, 2009
Methods

Direct multiplex sequencing (DMPS)—a novel method for targeted high-throughput sequencing of ancient and highly degraded DNA

  • First Published July 27, 2009
Letter

Xenopus tropicalis" > Abundant and dynamically expressed miRNAs, piRNAs, and other small RNAs in the vertebrate Xenopus tropicalis

  • First Published July 23, 2009
Methods

Quantitative phenotyping via deep barcode sequencing

  • First Published July 21, 2009
Letter

Relaxation of selective constraints on avian mitochondrial DNA following the degeneration of flight ability

  • First Published July 17, 2009
Methods

A probabilistic approach for SNP discovery in high-throughput human resequencing data

  • First Published July 15, 2009
Resource

Instrumenting the health care enterprise for discovery research in the genomic era

  • First Published July 14, 2009
Methods

Identification of deleterious mutations within three human genomes

  • First Published July 14, 2009
Resource

The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine

  • First Published July 14, 2009
Commentary

Every genome sequence needs a good map

  • First Published July 13, 2009
Resource

High-resolution mapping and analysis of copy number variations in the human genome: A data resource for clinical and research applications

  • First Published July 10, 2009
Letter

Unusual composition of a yeast chromosome arm is associated with its delayed replication

  • First Published July 10, 2009
Resource

RazerS—fast read mapping with sensitivity control

  • First Published July 10, 2009
Letter

Clusters and superclusters of phased small RNAs in the developing inflorescence of rice

  • First Published July 7, 2009
Letter

Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences

  • First Published July 7, 2009
Methods

High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing

  • First Published July 6, 2009
Methods

Transcriptional and post-transcriptional profile of human chromosome 21

  • First Published July 6, 2009
Letter

High-resolution analysis of epigenetic changes associated with X inactivation

  • First Published July 6, 2009
Methods

Identification of rare cancer driver mutations by network reconstruction

  • First Published July 2, 2009
Resource

JBrowse: A next-generation genome browser

  • First Published July 1, 2009
Letter

Escherichia coli O157 genomes" > Inference of the impact of insertion sequence (IS) elements on bacterial genome diversification through analysis of small-size structural polymorphisms in Escherichia coli O157 genomes

  • First Published June 29, 2009
Resource

mGene: Accurate SVM-based gene finding with an application to nematode genomes

  • First Published June 29, 2009
Resource

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

  • First Published June 23, 2009
Letter

0→G1 transition" > Epigenetics of human T cells during the G0→G1 transition

  • First Published June 22, 2009
Methods

Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding

  • First Published June 22, 2009
Letter

Arabidopsis pollen development and function" > Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and function

  • First Published June 22, 2009
Methods

Positional conservation and amino acids shape the correct diagnosis and population frequencies of benign and damaging personal amino acid mutations

  • First Published June 22, 2009
Letter

Epigenetic profiling at mouse imprinted gene clusters reveals novel epigenetic and genetic features at differentially methylated regions

  • First Published June 19, 2009
Methods

Can the whole be less than the sum of its parts? Pathway analysis in genome-scale metabolic networks using elementary flux patterns

  • First Published June 18, 2009
Methods

Next-generation tag sequencing for cancer gene expression profiling

  • First Published June 18, 2009
Methods

Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing

  • First Published June 18, 2009
Resource

Circos: An information aesthetic for comparative genomics

  • First Published June 18, 2009
Resource

Evidence-based gene predictions in plant genomes

  • First Published June 18, 2009
Methods

Genome-wide comparisons of variation in linkage disequilibrium

  • First Published June 18, 2009
Letter

Drosophila ovary cell line" > Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line

  • First Published June 18, 2009
Methods

Multiplex padlock targeted sequencing reveals human hypermutable CpG variations

  • First Published June 12, 2009
Article

Saccharomycetaceae" > Comparative genomics of protoploid Saccharomycetaceae

  • First Published June 12, 2009
Methods

A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease

  • First Published June 8, 2009
Letter

Ride the wavelet: A multiscale analysis of genomic contexts flanking small insertions and deletions

  • First Published June 5, 2009
Letter

The consequences of genetic drift for bacterial genome complexity

  • First Published June 5, 2009
Resource

The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes

  • First Published June 4, 2009
Letter

Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity

  • First Published June 3, 2009
Methods

Genome-wide screen of promoter methylation identifies novel markers in melanoma

  • First Published June 2, 2009
Resource

The first Korean genome sequence and analysis: Full genome sequencing for a socio-ethnic group

  • First Published May 26, 2009
Resource

Automated identification of conserved synteny after whole-genome duplication

  • First Published May 22, 2009
Methods

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

  • First Published May 21, 2009
Methods

Drosophila melanogaster" > Conserved introns reveal novel transcripts in Drosophila melanogaster

  • First Published May 20, 2009
Methods

Incorporating nucleosomes into thermodynamic models of transcription regulation

  • First Published May 18, 2009
Letter

Horizontal gene transfer of an entire metabolic pathway between a eukaryotic alga and its DNA virus

  • First Published May 18, 2009
Methods

Overlapping pools for high-throughput targeted resequencing

  • First Published May 15, 2009
Methods

DNA Sudoku—harnessing high-throughput sequencing for multiplexed specimen analysis

  • First Published May 15, 2009
Methods

Combinatorial algorithms for structural variation detection in high-throughput sequenced genomes

  • First Published May 15, 2009
Methods

Shifted Transversal Design smart-pooling for high coverage interactome mapping

  • First Published May 15, 2009
Methods

MS-qFRET: A quantum dot-based method for analysis of DNA methylation

  • First Published May 14, 2009
Letter

Domain shuffling and the evolution of vertebrates

  • First Published May 14, 2009
Letter

Evolution of gene function and regulatory control after whole-genome duplication: Comparative analyses in vertebrates

  • First Published May 13, 2009
Letter

Does the human X contain a third evolutionary block? Origin of genes on human Xp11 and Xq28

  • First Published May 13, 2009
Resource

Efficient frequency-based de novo short-read clustering for error trimming in next-generation sequencing

  • First Published May 13, 2009
Letter

Mobile elements create structural variation: Analysis of a complete human genome

  • First Published May 13, 2009
Letter

Drosophila melanogaster spontaneous mutation accumulation lines" > Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines

  • First Published May 13, 2009
Methods

Mapping epigenetic mutations in fission yeast using whole-genome next-generation sequencing

  • First Published May 7, 2009
Methods

High-throughput genotyping by whole-genome resequencing

  • First Published May 6, 2009
Letter

Large-scale mRNA sequencing determines global regulation of RNA editing during brain development

  • First Published May 6, 2009
Resource

SNP detection for massively parallel whole-genome resequencing

  • First Published May 6, 2009
Letter

CD44 contribute to acetaminophen-induced liver injury in humans" > Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

  • First Published May 5, 2009
Resource

Recovering genome rearrangements in the mammalian phylogeny

  • First Published May 1, 2009
Preface

On the origin of Darwinism

  • First Published May 1, 2009
Letter

Evolutionary descent of a human chromosome 6 neocentromere: A jump back to 17 million years ago

  • First Published May 1, 2009
Perspective

Evolution under canalization and the dual roles of microRNAs—A hypothesis

  • First Published May 1, 2009
Letter

Alu repeats in primate genomes" > Comparative analysis of Alu repeats in primate genomes

  • First Published May 1, 2009
Methods

The difficulty of avoiding false positives in genome scans for natural selection

  • First Published May 1, 2009
Perspective

Non-Darwinian estimation: My ancestors, my genes' ancestors

  • First Published May 1, 2009
Letter

Drosophila" > Proteomic discovery of previously unannotated, rapidly evolving seminal fluid genes in Drosophila

  • First Published May 1, 2009
Article

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes

  • First Published May 1, 2009
Letter

Fine-scaled human genetic structure revealed by SNP microarrays

  • First Published May 1, 2009
Perspective

Genetic architecture of quantitative traits in mice, flies, and humans

  • First Published May 1, 2009
Commentary

One hundred fifty years without Darwin are enough!

  • First Published May 1, 2009
Letter

Adaptive evolution of young gene duplicates in mammals

  • First Published May 1, 2009
Perspective

On the origin of prokaryotic species

  • First Published May 1, 2009
Erratum

Erratum

  • First Published May 1, 2009
Letter

The polyadenylation site of Mimivirus transcripts obeys a stringent ‘hairpin rule’

  • First Published April 29, 2009
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