Your search for returned 6,372 results
Research
Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription
- First Published January 21, 2015
Resource
lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines" > A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines
- First Published January 15, 2015
Resource
Drosophila melanogaster genome" > The Release 6 reference sequence of the Drosophila melanogaster genome
- First Published January 14, 2015
Method
Single-cell-level spatial gene expression in the embryonic neural differentiation niche
- First Published January 9, 2015
Method
Efficient inference of population size histories and locus-specific mutation rates from large-sample genomic variation data
- First Published January 6, 2015
Research
RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts
- First Published December 18, 2014
Research
Candida albicans" > Genetic and phenotypic intra-species variation in Candida albicans
- First Published December 11, 2014
Research
Asymmetric nucleosomes flank promoters in the budding yeast genome
- First Published December 9, 2014
Research
Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline
- First Published December 5, 2014
Research
A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes
- First Published December 1, 2014
Research
Decoupling of evolutionary changes in transcription factor binding and gene expression in mammals
- First Published November 13, 2014
Research
TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity
- First Published November 12, 2014
Method
The discovery of integrated gene networks for autism and related disorders
- First Published November 5, 2014
Method
Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks
- First Published November 5, 2014
Research
Escherichia coli strains" > Large-scale genomic sequencing of extraintestinal pathogenic Escherichia coli strains
- First Published November 4, 2014
Research
Genome accessibility is widely preserved and locally modulated during mitosis
- First Published November 4, 2014
Resource
Single haplotype assembly of the human genome from a hydatidiform mole
- First Published November 4, 2014
Method
Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line
- First Published November 4, 2014
Research
Large transcription units unify copy number variants and common fragile sites arising under replication stress
- First Published November 4, 2014
Research
C. elegans and ADAR mutants" > Profiling the RNA editomes of wild-type C. elegans and ADAR mutants
- First Published November 4, 2014
Research
Arabidopsis thaliana" > Genome-wide analysis of local chromatin packing in Arabidopsis thaliana
- First Published November 3, 2014
Research
Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes
- First Published November 3, 2014
Research
Two new insulator proteins, Pita and ZIPIC, target CP190 to chromatin
- First Published October 23, 2014
Research
Neurospora: the role of mutational bias and selection" > Intron evolution in Neurospora: the role of mutational bias and selection
- First Published October 23, 2014
Method
In vitro, long-range sequence information for de novo genome assembly via transposase contiguity
- First Published October 19, 2014
Research
Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis
- First Published October 15, 2014
Research
Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis
- First Published October 15, 2014
Research
Widespread contribution of transposable elements to the innovation of gene regulatory networks
- First Published October 15, 2014
Research
Arabidopsis thaliana mutations and epimutations" > Environmentally responsive genome-wide accumulation of de novo Arabidopsis thaliana mutations and epimutations
- First Published October 14, 2014
Research
Estimating genotype error rates from high-coverage next-generation sequence data
- First Published October 10, 2014
Method
Application of histone modification-specific interaction domains as an alternative to antibodies
- First Published October 9, 2014
Research
Accounting for biases in riboprofiling data indicates a major role for proline in stalling translation
- First Published October 7, 2014
Research
Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal
- First Published October 7, 2014
Research
Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters
- First Published October 7, 2014
Method
Parente2: a fast and accurate method for detecting identity by descent
- First Published October 1, 2014
Resource
Alignathon: a competitive assessment of whole-genome alignment methods
- First Published October 1, 2014
Research
H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells
- First Published September 30, 2014
Research
Drosophila ovarian cell cultures" > Transposable element dynamics and PIWI regulation impacts lncRNA and gene expression diversity in Drosophila ovarian cell cultures
- First Published September 29, 2014
Research
U2AF1 mutations alter splice site recognition in hematological malignancies" > U2AF1 mutations alter splice site recognition in hematological malignancies
- First Published September 29, 2014
Method
Drosophila melanogaster" > Large-scale identification of chemically induced mutations in Drosophila melanogaster
- First Published September 25, 2014
Research
Widespread intron retention in mammals functionally tunes transcriptomes
- First Published September 25, 2014
Research
Genetic and environmental exposures constrain epigenetic drift over the human life course
- First Published September 23, 2014
Research
Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles" > Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles
- First Published September 18, 2014
Research
Genome-wide map of regulatory interactions in the human genome
- First Published September 16, 2014
Research
Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication
- First Published September 16, 2014
Research
Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia" > Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
- First Published September 15, 2014
Method
A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness
- First Published September 12, 2014
Research
Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition
- First Published September 12, 2014
Research
Systems consequences of amplicon formation in human breast cancer
- First Published September 3, 2014
Resource
OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines
- First Published September 3, 2014
Method
Linking signaling pathways to transcriptional programs in breast cancer
- First Published September 2, 2014
Research
Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways
- First Published August 28, 2014
Research
Saccharomyces cerevisiae" > Preservation of genetic and regulatory robustness in ancient gene duplicates of Saccharomyces cerevisiae
- First Published August 22, 2014
Research
H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress
- First Published August 18, 2014
Method
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C
- First Published August 13, 2014
Research
High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface
- First Published August 13, 2014
Method
piggyBac" > Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac
- First Published August 5, 2014
Research
Cell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing
- First Published August 5, 2014
Research
Plasmodium falciparum" > Interactive transcriptome analysis of malaria patients and infecting Plasmodium falciparum
- First Published August 4, 2014
Research
Differential retention and divergent resolution of duplicate genes following whole-genome duplication
- First Published August 1, 2014
Method
Selective enrichment of damaged DNA molecules for ancient genome sequencing
- First Published July 31, 2014
Method
Tn5 transposase and tagmentation procedures for massively scaled sequencing projects
- First Published July 30, 2014
Research
Error-prone polymerase activity causes multinucleotide mutations in humans
- First Published July 30, 2014
Method
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
- First Published July 24, 2014
Research
Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate
- First Published July 21, 2014
Research
The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity
- First Published July 21, 2014
Research
Noncoding origins of anthropoid traits and a new null model of transposon functionalization
- First Published July 20, 2014
Research
High-throughput functional testing of ENCODE segmentation predictions
- First Published July 17, 2014
Method
Probing the effect of promoters on noise in gene expression using thousands of designed sequences
- First Published July 16, 2014
Research
COL2A1 gene alteration in chondrosarcoma" > Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma
- First Published July 14, 2014
Research
Evolutionarily diverse determinants of meiotic DNA break and recombination landscapes across the genome
- First Published July 14, 2014
Research
T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity
- First Published July 14, 2014
Method
Decoding ChIP-seq with a double-binding signal refines binding peaks to single-nucleotides and predicts cooperative interaction
- First Published July 14, 2014
Research
Genomic analysis of the causative agents of coccidiosis in domestic chickens
- First Published July 11, 2014
Research
RSC-dependent constructive and destructive interference between opposing arrays of phased nucleosomes in yeast
- First Published July 11, 2014
Method
High resolution mapping of modified DNA nucleobases using excision repair enzymes
- First Published July 11, 2014
Method
Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases
- First Published July 2, 2014
Resource
Drosophila cell lines" > Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines
- First Published July 1, 2014
Resource
D. melanogaster modENCODE transcriptome annotation" > Comparative validation of the D. melanogaster modENCODE transcriptome annotation
- First Published July 1, 2014
Resource
Drosophila melanogaster" > Diverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster
- First Published July 1, 2014
Research
DNA replication and transcription programs respond to the same chromatin cues
- First Published July 1, 2014
Research
Evolution of H3K27me3-marked chromatin is linked to gene expression evolution and to patterns of gene duplication and diversification
- First Published July 1, 2014