Your search for returned 6,372 results
Resource
Transcription initiation mapping in 31 bovine tissues reveals complex promoter activity, pervasive transcription, and tissue-specific promoter usage
- First Published March 15, 2021
Research
ZNF91 deletion in human embryonic stem cells leads to ectopic activation of SVA retrotransposons and up-regulation of KRAB zinc finger gene clusters" > ZNF91 deletion in human embryonic stem cells leads to ectopic activation of SVA retrotransposons and up-regulation of KRAB zinc finger gene clusters
- First Published March 15, 2021
Research
Improved redox homeostasis owing to the up-regulation of one-carbon metabolism and related pathways is crucial for yeast heterosis at high temperature
- First Published March 15, 2021
Method
Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data
- First Published March 15, 2021
Research
A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cells
- First Published March 12, 2021
Research
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia
- First Published March 11, 2021
Method
A plug and play microfluidic platform for standardized sensitive low-input chromatin immunoprecipitation
- First Published March 11, 2021
Research
Genomic analyses provide insights into peach local adaptation and responses to climate change
- First Published March 9, 2021
Research
AP-1 subunits converge promiscuously at enhancers to potentiate transcription
- First Published March 5, 2021
Method
Modeling expression ranks for noise-tolerant differential expression analysis of scRNA-seq data
- First Published March 5, 2021
Research
Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver
- First Published March 1, 2021
Method
Semisupervised adversarial neural networks for single-cell classification
- First Published February 24, 2021
Method
Linear-time cluster ensembles of large-scale single-cell RNA-seq and multimodal data
- First Published February 24, 2021
Research
SARS-CoV-2 genomic diversity and the implications for qRT-PCR diagnostics and transmission
- First Published February 18, 2021
Research
Sir3 mediates long-range chromosome interactions in budding yeast
- First Published February 12, 2021
Method
A minimally destructive protocol for DNA extraction from ancient teeth
- First Published February 12, 2021
Method
Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs
- First Published February 11, 2021
Research
Rtt109 slows replication speed by histone N-terminal acetylation
- First Published February 9, 2021
Research
Drosophila simulans species complex" > Evolution of genome structure in the Drosophila simulans species complex
- First Published February 9, 2021
Research
Drosophila" > Topologically associating domains and their role in the evolution of genome structure and function in Drosophila
- First Published February 9, 2021
Research
Fixation of allelic gene expression landscapes and expression bias pattern shape the transcriptome of the clonal Amazon molly
- First Published February 5, 2021
Research
Low-pass sequencing increases the power of GWAS and decreases measurement error of polygenic risk scores compared to genotyping arrays
- First Published February 3, 2021
Research
Abundantly expressed class of noncoding RNAs conserved through the multicellular evolution of dictyostelid social amoebas
- First Published January 21, 2021
Research
Dosage-sensitive functions in embryonic development drove the survival of genes on sex-specific chromosomes in snakes, birds, and mammals
- First Published January 21, 2021
Resource
A platform for curated products from novel open reading frames prompts reinterpretation of disease variants
- First Published January 19, 2021
Research
Allele-specific alternative splicing and its functional genetic variants in human tissues
- First Published January 15, 2021
Method
Contamination detection in sequencing studies using the mitochondrial phylogeny
- First Published January 15, 2021
Research
Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease
- First Published January 13, 2021
Resource
Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognition
- First Published January 13, 2021
Method
Accurate and efficient detection of gene fusions from RNA sequencing data
- First Published January 13, 2021
Research
Post-transcriptional circadian regulation in macrophages organizes temporally distinct immunometabolic states
- First Published January 12, 2021
Resource
A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons
- First Published January 8, 2021
Research
KDM1A maintains genome-wide homeostasis of transcriptional enhancers
- First Published January 7, 2021
Resource
A new emu genome illuminates the evolution of genome configuration and nuclear architecture of avian chromosomes
- First Published January 6, 2021
Method
Effects of transcriptional noise on estimates of gene and transcript expression in RNA sequencing experiments
- First Published December 23, 2020
Research
Transporter genes in biosynthetic gene clusters predict metabolite characteristics and siderophore activity
- First Published December 23, 2020
Resource
Modeling molecular development of breast cancer in canine mammary tumors
- First Published December 23, 2020
Method
Transcript assembly improves expression quantification of transposable elements in single-cell RNA-seq data
- First Published December 21, 2020
Method
DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution
- First Published December 21, 2020
Method
Genome-wide prediction of DNA mutation effect on nucleosome positions for yeast synthetic genomics
- First Published December 18, 2020
Method
TSA-seq reveals a largely conserved genome organization relative to nuclear speckles with small position changes tightly correlated with gene expression changes
- First Published December 18, 2020
Research
Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development
- First Published December 18, 2020
Research
Arabidopsis thaliana mutation rate" > Thermal stress accelerates Arabidopsis thaliana mutation rate
- First Published December 17, 2020
Research
Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis
- First Published December 16, 2020
Review
k-mers for querying large collections of sequencing data sets" > Data structures based on k-mers for querying large collections of sequencing data sets
- First Published December 16, 2020
Method
i-GONAD method" > Generation of mouse conditional knockout alleles in one step using the i-GONAD method
- First Published December 16, 2020
Method
Evidence of widespread, independent sequence signature for transcription factor cobinding
- First Published December 10, 2020
Method
Epigenomic differences in the human and chimpanzee genomes are associated with structural variation
- First Published December 10, 2020
Resource
Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders
- First Published December 3, 2020
Corrigendum
Corrigendum: Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians
- First Published December 1, 2020
Resource
Accessing NCBI data using the NCBI Sequence Viewer and Genome Data Viewer (GDV)
- First Published November 25, 2020
Research
Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules
- First Published November 25, 2020
Research
The origin and evolution of a distinct mechanism of transcription initiation in yeasts
- First Published November 20, 2020
Method
Predictive modeling of single-cell DNA methylome data enhances integration with transcriptome data
- First Published November 20, 2020
Research
Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages" > Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages
- First Published November 18, 2020
Method
MAnorm2 for quantitatively comparing groups of ChIP-seq samples
- First Published November 18, 2020
Method
Identifying chromosomal subpopulations based on their recombination histories advances the study of the genetic basis of phenotypic traits
- First Published November 17, 2020
Method
Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time
- First Published November 17, 2020
Method
Predicting unrecognized enhancer-mediated genome topology by an ensemble machine learning model
- First Published November 12, 2020
Research
C. elegans" > Loss of histone H3.3 results in DNA replication defects and altered origin dynamics in C. elegans
- First Published November 10, 2020
Research
C. elegans" > Global regulatory features of alternative splicing across tissues and within the nervous system of C. elegans
- First Published October 30, 2020
Research
Complex mosaic structural variations in human fetal brains
- First Published October 29, 2020
Method
Identification of bona fide B2 SINE retrotransposon transcription through single-nucleus RNA-seq of the mouse hippocampus
- First Published October 29, 2020
Research
Sequencing identifies multiple early introductions of SARS-CoV-2 to the New York City region
- First Published October 22, 2020
Research
C. elegans" > Distinctive regulatory architectures of germline-active and somatic genes in C. elegans
- First Published October 22, 2020
Resource
Single-cell strand sequencing of a macaque genome reveals multiple nested inversions and breakpoint reuse during primate evolution
- First Published October 22, 2020
Research
A systems genetics approach reveals environment-dependent associations between SNPs, protein coexpression, and drought-related traits in maize
- First Published October 15, 2020
Research
Active retrotransposons help maintain pericentromeric heterochromatin required for faithful cell division
- First Published October 15, 2020
Method
Ultrafast and scalable variant annotation and prioritization with big functional genomics data
- First Published October 15, 2020
Method
Accurate reconstruction of bacterial pan- and core genomes with PEPPAN
- First Published October 14, 2020
Research
Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains
- First Published October 14, 2020
Research
Large tandem duplications affect gene expression, 3D organization, and plant–pathogen response
- First Published October 8, 2020
Research
An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation
- First Published October 5, 2020
Method
Genome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling
- First Published September 25, 2020
Method
Agonist-induced functional analysis and cell sorting associated with single-cell transcriptomics characterizes cell subtypes in normal and pathological brain
- First Published September 24, 2020
Research
Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants
- First Published September 24, 2020
Method
Identification of determinants of differential chromatin accessibility through a massively parallel genome-integrated reporter assay
- First Published September 24, 2020
Research
Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis
- First Published September 23, 2020
Research
Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors
- First Published September 22, 2020
Resource
Pan-cancer multi-omics analysis and orthogonal experimental assessment of epigenetic driver genes
- First Published September 22, 2020
Method
Reconstructing double-stranded DNA fragments on a single-molecule level reveals patterns of degradation in ancient samples
- First Published September 22, 2020
Method
PRAM: a novel pooling approach for discovering intergenic transcripts from large-scale RNA sequencing experiments
- First Published September 21, 2020
Research
V(DD)J recombination is an important and evolutionarily conserved mechanism for generating antibodies with unusually long CDR3s
- First Published September 18, 2020
Method
Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease
- First Published September 18, 2020
Corrigendum
Corrigendum: Functional annotation of human long noncoding RNAs via molecular phenotyping
- First Published September 14, 2020
Corrigendum
Corrigendum: 3′ UTR lengthening as a novel mechanism in regulating cellular senescence
- First Published September 14, 2020
Method
Molecular barcoding of native RNAs using nanopore sequencing and deep learning
- First Published September 9, 2020
Method
Reconstruction of clone- and haplotype-specific cancer genome karyotypes from bulk tumor samples
- First Published September 4, 2020