Volume 32, Issue 3 | March 2022

In memoriam
- - C. Thomas Caskey (1938–2022)
    Richard A. Gibbs
    Aravinda Chakravarti
    Evan E. Eichler
    Eric D. Green
    Richard M. Myers
    First Published February 17, 2022
Research
- - Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations
    Anu Toropainen
    Lindsey K. Stolze
    Tiit Örd
    Michael B. Whalen
    Paula Martí Torrell
    First Published February 22, 2022
  - Genomic context sensitivity of insulator function
    André M. Ribeiro-dos-Santos
    Megan S. Hogan
    Raven D. Luther
    Ran Brosh
    Matthew T. Maurano
    First Published January 26, 2022
  - Enhancer–silencer transitions in the human genome
    Di Huang
    Ivan Ovcharenko
    First Published February 1, 2022
  - Whole-genome resequencing of temporally stratified samples reveals substantial loss of haplotype diversity in the highly inbred Scandinavian wolf population
    Agnese Viluma
    Øystein Flagstad
    Mikael Åkesson
    Camilla Wikenros
    Håkan Sand
    First Published February 8, 2022
  - Joint actions of diverse transcription factor families establish neuron-type identities and promote enhancer selectivity
    Angela Jimeno-Martín
    Erick Sousa
    Rebeca Brocal-Ruiz
    Noemi Daroqui
    Miren Maicas
    First Published January 24, 2022
  - Distal regulation, silencers, and a shared combinatorial syntax are hallmarks of animal embryogenesis
    Paola Cornejo-Páramo
    Kathrein Roper
    Sandie M. Degnan
    Bernard M. Degnan
    Emily S. Wong
    First Published January 19, 2022
Methods
- - De novo mutation rates at the single-mutation resolution in a human HBB gene region associated with adaptation and genetic disease
    Daniel Melamed
    Yuval Nov
    Assaf Malik
    Michael B. Yakass
    Evgeni Bolotin
    First Published January 14, 2022
  - Discovery of an unusually high number of de novo mutations in sperm of older men using duplex sequencing
    Renato Salazar
    Barbara Arbeithuber
    Maja Ivankovic
    Monika Heinzl
    Sofia Moura
    Ingrid Hartl Theresa Mair Angelika Lahnsteiner
    ...[+3 authors]...,
    Thomas Ebner
    Omar Shebl
    Johannes Pröll
    Irene Tiemann-Boege
    First Published February 24, 2022
  - Domain-adaptive neural networks improve cross-species prediction of transcription factor binding
    Kelly Cochran
    Divyanshi Srivastava
    Avanti Shrikumar
    Akshay Balsubramani
    Ross C. Hardison
    First Published January 18, 2022
  - Predicting genotype-specific gene regulatory networks
    Deborah Weighill
    Marouen Ben Guebila
    Kimberly Glass
    John Quackenbush
    John Platig
    First Published February 22, 2022
  - NicE-C efficiently reveals open chromatin–associated chromosome interactions at high resolution
    Zhengyu Luo
    Ran Zhang
    Tengfei Hu
    Yuting Zhu
    Yueming Wu
    Wenfei Li
    ...[+1 authors]...,
    Zhi Zhang
    Xuebiao Yao
    Haiyi Liang
    Xiaoyuan Song
    First Published February 1, 2022
  - Low-input RNase footprinting for simultaneous quantification of cytosolic and mitochondrial translation
    Qianru Li
    Haiwang Yang
    Emily K. Stroup
    Hongbin Wang
    Zhe Ji
    First Published February 22, 2022
  - Accurate and robust inference of microbial growth dynamics from metagenomic sequencing reveals personalized growth rates
    Tyler A. Joseph
    Philippe Chlenski
    Aviya Litman
    Tal Korem
    Itsik Pe'er
    First Published January 5, 2022
Resources
- - Mitochondrial DNA variation across 56,434 individuals in gnomAD
    Kristen M. Laricchia
    Nicole J. Lake
    Nicholas A. Watts
    Megan Shand
    Andrea Haessly
    Laura Gauthier David Benjamin Eric Banks Jose Soto Kiran Garimella James Emery Heidi L. Rehm Daniel G. MacArthur
    ...[+8 authors]...,
    Grace Tiao
    Monkol Lek
    Vamsi K. Mootha
    Sarah E. Calvo
    First Published January 24, 2022
  - Genome biology of the darkedged splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentation
    Kang Du
    Martin Pippel
    Susanne Kneitz
    Romain Feron
    Irene da Cruz
    Sylke Winkler Brigitta Wilde Edgar G. Avila Luna
    ...[+3 authors]...,
    Gene Myers
    Yann Guiguen
    Constantino Macias Garcia
    Manfred Schartl
    First Published January 26, 2022

Table of Contents

Volume 32, Issue 3 | March 2022

In memoriam

C. Thomas Caskey (1938–2022)

Research

Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations

Genomic context sensitivity of insulator function

Enhancer–silencer transitions in the human genome

Whole-genome resequencing of temporally stratified samples reveals substantial loss of haplotype diversity in the highly inbred Scandinavian wolf population

Joint actions of diverse transcription factor families establish neuron-type identities and promote enhancer selectivity

Distal regulation, silencers, and a shared combinatorial syntax are hallmarks of animal embryogenesis

Methods

De novo mutation rates at the single-mutation resolution in a human HBB gene region associated with adaptation and genetic disease

Discovery of an unusually high number of de novo mutations in sperm of older men using duplex sequencing

Domain-adaptive neural networks improve cross-species prediction of transcription factor binding

Predicting genotype-specific gene regulatory networks

NicE-C efficiently reveals open chromatin–associated chromosome interactions at high resolution

Low-input RNase footprinting for simultaneous quantification of cytosolic and mitochondrial translation

Accurate and robust inference of microbial growth dynamics from metagenomic sequencing reveals personalized growth rates

Resources

Mitochondrial DNA variation across 56,434 individuals in gnomAD

Genome biology of the darkedged splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentation

Table of Contents

Volume 32, Issue 3 | March 2022

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In memoriam

Research

Methods

Resources