Volume 32, Issue 10 | October 2022

Research
- - Mosaic loss of Chromosome Y in aged human microglia
    Michael C. Vermeulen
    Richard Pearse
    Tracy Young-Pearse
    Sara Mostafavi
    First Published August 30, 2022
  - Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis
    Marija Petrić Howe
    Hamish Crerar
    Jacob Neeves
    Jasmine Harley
    Giulia E. Tyzack
    First Published September 30, 2022
  - Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels
    Amanda J. Lea
    Julie Peng
    Julien F. Ayroles
    First Published October 13, 2022
  - Functional characterization of enhancer activity during a long terminal repeat's evolution
    Alan Y. Du
    Xiaoyu Zhuo
    Vasavi Sundaram
    Nicholas O. Jensen
    Hemangi G. Chaudhari
    First Published October 3, 2022
  - Natural variation in C. elegans short tandem repeats
    Gaotian Zhang
    Ye Wang
    Erik C. Andersen
    First Published October 4, 2022
  - A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility
    Angelo A. Ruggieri
    Luca Livraghi
    James J. Lewis
    Elizabeth Evans
    Francesco Cicconardi
    Laura Hebberecht Yadira Ortiz-Ruiz Stephen H. Montgomery Alfredo Ghezzi José Arcadio Rodriguez-Martinez Chris D. Jiggins
    ...[+6 authors]...,
    W. Owen McMillan
    Brian A. Counterman
    Riccardo Papa
    Steven M. Van Belleghem
    First Published September 15, 2022
Methods
- - Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells
    Keyi Geng
    Lara G. Merino
    Linda Wedemann
    Aniek Martens
    Małgorzata Sobota
    First Published September 30, 2022
  - Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling
    Stephanie M. Zimmerman
    Robin Fropf
    Bridget R. Kulasekara
    Maddy Griswold
    Oliver Appelbe
    Arya Bahrami Rich Boykin Derek L. Buhr Kit Fuhrman Margaret L. Hoang Quoc Huynh Lesley Isgur Andrew Klock Alecksandr Kutchma Alexa E. Lasley Yan Liang Jill McKay-Fleisch Jeffrey S. Nelson Karen Nguyen Erin Piazza
    ...[+15 authors]...,
    Aric Rininger
    Daniel R. Zollinger
    Michael Rhodes
    Joseph M. Beechem
    First Published September 13, 2022
  - A model-based constrained deep learning clustering approach for spatially resolved single-cell data
    Xiang Lin
    Le Gao
    Nathan Whitener
    Ashley Ahmed
    Zhi Wei
    First Published October 5, 2022
  - A statistical physics approach for disease module detection
    Xu-Wen Wang
    Dandi Qiao
    Michael H. Cho
    Dawn L. DeMeo
    Edwin K. Silverman
    First Published October 11, 2022
  - Surveying mutation density patterns around specific genomic features
    Hui Yu
    Scott Ness
    Chung-I Li
    Yongsheng Bai
    Peng Mao
    First Published September 13, 2022
Resources
- - A high-resolution map of small-scale inversions in the gibbon genome
    Ludovica Mercuri
    Donato Palmisano
    Alberto L'Abbate
    Pietro D'Addabbo
    Francesco Montinaro
    Claudia Rita Catacchio Patrick Hasenfeld Mario Ventura
    ...[+3 authors]...,
    Jan O. Korbel
    Ashley D. Sanders
    Flavia Angela Maria Maggiolini
    Francesca Antonacci
    First Published September 30, 2022
  - The western redcedar genome reveals low genetic diversity in a self-compatible conifer
    Tal J. Shalev
    Omnia Gamal El-Dien
    Macaire M.S. Yuen
    Shu Shengqiang
    Shaun D. Jackman
    René L. Warren Lauren Coombe Lise van der Merwe Ada Stewart Lori B. Boston Christopher Plott Jerry Jenkins Guifen He Juying Yan Mi Yan Jie Guo Jesse W. Breinholt Leandro G. Neves Jane Grimwood Loren H. Rieseberg Jeremy Schmutz Inanc Birol Matias Kirst
    ...[+18 authors]...,
    Alvin D. Yanchuk
    Carol Ritland
    John H. Russell
    Joerg Bohlmann
    First Published September 15, 2022
Corrigenda
- - Corrigendum: Cell cycle arrest explains the observed bulk 3D genomic alterations in response to long-term heat shock in K562 cells
    Bingxiang Xu
    Xiaomeng Gao
    Xiaoli Li
    Yan Jia
    Feifei Li
    First Published November 2, 2022
  - Corrigendum: Diversifying the genomic data science research community
    First Published November 2, 2022

Table of Contents

Volume 32, Issue 10 | October 2022

Research

Mosaic loss of Chromosome Y in aged human microglia

Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis

Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels

Functional characterization of enhancer activity during a long terminal repeat's evolution

Natural variation in C. elegans short tandem repeats

A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility

Methods

Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells

Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling

A model-based constrained deep learning clustering approach for spatially resolved single-cell data

A statistical physics approach for disease module detection

Surveying mutation density patterns around specific genomic features

Resources

A high-resolution map of small-scale inversions in the gibbon genome

The western redcedar genome reveals low genetic diversity in a self-compatible conifer

Corrigenda

Corrigendum: Cell cycle arrest explains the observed bulk 3D genomic alterations in response to long-term heat shock in K562 cells

Corrigendum: Diversifying the genomic data science research community

Table of Contents

Volume 32, Issue 10 | October 2022

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Research

Methods

Resources

Corrigenda