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Table of Contents
September 2021; 31 (9)
Research
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Differences in the number of de novo mutations between individuals are due to small family-specific effects and stochasticity
Jakob M. Goldmann
,
Juliet E. Hampstead
,
Wendy S.W. Wong
,
Amy B. Wilfert
,
Tychele N. Turner
,
Marianne A. Jonker
,
Raphael Bernier
,
Martijn A. Huynen
,
Evan E. Eichler
,
Joris A. Veltman
,
George L. Maxwell
,
and
Christian Gilissen
Genome Res.
September 2021
31
:
1513
-
1518
;
Published in Advance
July 23, 2021
,
doi:
10.1101/gr.271809.120
Abstract
Full Text
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Parental methylome reprogramming in human uniparental blastocysts reveals germline memory transition
Jiawei Xu
,
Yimin Shu
,
Guidong Yao
,
Yu Zhang
,
Wenbin Niu
,
Yile Zhang
,
Xueshan Ma
,
Haixia Jin
,
Fuli Zhang
,
Senlin Shi
,
Yang Wang
,
Wenyan Song
,
Shanjun Dai
,
Luyao Cheng
,
Xiangyang Zhang
,
Wei Xie
,
Aaron J. Hsueh
,
and
Yingpu Sun
Genome Res.
September 2021
31
:
1519
-
1530
;
Published in Advance
July 30, 2021
,
doi:
10.1101/gr.273318.120
Abstract
Full Text
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Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brain
Christopher J. Playfoot
,
Julien Duc
,
Shaoline Sheppard
,
Sagane Dind
,
Alexandre Coudray
,
Evarist Planet
,
and
Didier Trono
Genome Res.
September 2021
31
:
1531
-
1545
;
Published in Advance
August 16, 2021
,
doi:
10.1101/gr.275133.120
Abstract
Full Text
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OPEN ACCESS ARTICLE
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Ligand-induced native G-quadruplex stabilization impairs transcription initiation
Conghui Li
,
Honghong Wang
,
Zhinang Yin
,
Pingping Fang
,
Ruijing Xiao
,
Ying Xiang
,
Wen Wang
,
Qiuzi Li
,
Beili Huang
,
Jian Huang
,
and
Kaiwei Liang
Genome Res.
September 2021
31
:
1546
-
1560
;
Published in Advance
August 16, 2021
,
doi:
10.1101/gr.275431.121
Abstract
Full Text
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Genome-wide variability in recombination activity is associated with meiotic chromatin organization
Xiaofan Jin
,
Geoff Fudenberg
,
and
Katherine S. Pollard
Genome Res.
September 2021
31
:
1561
-
1572
;
Published in Advance
July 23, 2021
,
doi:
10.1101/gr.275358.121
Abstract
Full Text
Full Text (PDF)
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OPEN ACCESS ARTICLE
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The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection
Jialin Liu
,
Rebecca R. Viales
,
Pierre Khoueiry
,
James P. Reddington
,
Charles Girardot
,
Eileen E.M. Furlong
,
and
Marc Robinson-Rechavi
Genome Res.
September 2021
31
:
1573
-
1581
;
Published in Advance
July 15, 2021
,
doi:
10.1101/gr.275212.121
Abstract
Full Text
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OPEN ACCESS ARTICLE
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Temperature dependence of spontaneous mutation rates
Ann-Marie Waldvogel
and
Markus Pfenninger
Genome Res.
September 2021
31
:
1582
-
1589
;
Published in Advance
July 23, 2021
,
doi:
10.1101/gr.275168.120
Abstract
Full Text
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Single worm transcriptomics identifies a developmental core network of oscillating genes with deep conservation across nematodes
Shuai Sun
,
Christian Rödelsperger
,
and
Ralf J. Sommer
Genome Res.
September 2021
31
:
1590
-
1601
;
Published in Advance
July 22, 2021
,
doi:
10.1101/gr.275303.121
Abstract
Full Text
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Mutability of mononucleotide repeats, not oxidative stress, explains the discrepancy between laboratory-accumulated mutations and the natural allele-frequency spectrum in
C. elegans
Moein Rajaei
,
Ayush Shekhar Saxena
,
Lindsay M. Johnson
,
Michael C. Snyder
,
Timothy A. Crombie
,
Robyn E. Tanny
,
Erik C. Andersen
,
Joanna Joyner-Matos
,
and
Charles F. Baer
Genome Res.
September 2021
31
:
1602
-
1613
;
Published in Advance
August 17, 2021
,
doi:
10.1101/gr.275372.121
Abstract
Full Text
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Crossover-active regions of the wheat genome are distinguished by DMC1, the chromosome axis, H3K27me3, and signatures of adaptation
Andrew J. Tock
,
Daniel M. Holland
,
Wei Jiang
,
Kim Osman
,
Eugenio Sanchez-Moran
,
James D. Higgins
,
Keith J. Edwards
,
Cristobal Uauy
,
F. Chris H. Franklin
,
and
Ian R. Henderson
Genome Res.
September 2021
31
:
1614
-
1628
;
Published in Advance
August 23, 2021
,
doi:
10.1101/gr.273672.120
Abstract
Full Text
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Methods
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Inferring genes that escape X-Chromosome inactivation reveals important contribution of variable escape genes to sex-biased diseases
Renan Sauteraud
,
Jill M. Stahl
,
Jesica James
,
Marisa Englebright
,
Fang Chen
,
Xiaowei Zhan
,
Laura Carrel
,
and
Dajiang J. Liu
Genome Res.
September 2021
31
:
1629
-
1637
;
Published in Advance
August 23, 2021
,
doi:
10.1101/gr.275677.121
Abstract
Full Text
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Sequence-based correction of barcode bias in massively parallel reporter assays
Dongwon Lee
,
Ashish Kapoor
,
Changhee Lee
,
Michael Mudgett
,
Michael A. Beer
,
and
Aravinda Chakravarti
Genome Res.
September 2021
31
:
1638
-
1645
;
Published in Advance
July 20, 2021
,
doi:
10.1101/gr.268599.120
Abstract
Full Text
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A universal framework for detecting
cis
-regulatory diversity in DNA regions
Anushua Biswas
and
Leelavati Narlikar
Genome Res.
September 2021
31
:
1646
-
1662
;
Published in Advance
July 19, 2021
,
doi:
10.1101/gr.274563.120
Abstract
Full Text
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Resources
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A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells
William K.M. Lai
,
Luca Mariani
,
Gerson Rothschild
,
Edwin R. Smith
,
Bryan J. Venters
,
Thomas R. Blanda
,
Prashant K. Kuntala
,
Kylie Bocklund
,
Joshua Mairose
,
Sarah N. Dweikat
,
Katelyn Mistretta
,
Matthew J. Rossi
,
Daniela James
,
James T. Anderson
,
Sabrina K. Phanor
,
Wanwei Zhang
,
Zibo Zhao
,
Avani P. Shah
,
Katherine Novitzky
,
Eileen McAnarney
,
Michael-C. Keogh
,
Ali Shilatifard
,
Uttiya Basu
,
Martha L. Bulyk
,
and
B. Franklin Pugh
Genome Res.
September 2021
31
:
1663
-
1679
;
Published in Advance
August 23, 2021
,
doi:
10.1101/gr.275472.121
Abstract
Full Text
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Global patterns of enhancer activity during sea urchin embryogenesis assessed by eRNA profiling
Jian Ming Khor
,
Jennifer Guerrero-Santoro
,
William Douglas
,
and
Charles A. Ettensohn
Genome Res.
September 2021
31
:
1680
-
1692
;
Published in Advance
July 30, 2021
,
doi:
10.1101/gr.275684.121
Abstract
Full Text
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September 2021;
31
(9)
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