Volume 31, Issue 12 | December 2021

Research
- - Delayed DNA replication in haploid human embryonic stem cells
    Matthew M. Edwards
    Michael V. Zuccaro
    Ido Sagi
    Qiliang Ding
    Dan Vershkov
    First Published November 22, 2021
  - Decoding the function of bivalent chromatin in development and cancer
    Dhirendra Kumar
    Senthilkumar Cinghu
    Andrew J. Oldfield
    Pengyi Yang
    Raja Jothi
    First Published October 19, 2021
  - Epstein–Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci
    Ted Hong
    Sreeja Parameswaran
    Omer A. Donmez
    Daniel Miller
    Carmy Forney
    Michael Lape Mariana Saint Just Ribeiro Jun Liang Lee E. Edsall Albert F. Magnusen William Miller Iouri Chepelev
    ...[+7 authors]...,
    John B. Harley
    Bo Zhao
    Leah C. Kottyan
    Matthew T. Weirauch
    First Published November 19, 2021
  - A multi-enhancer RET regulatory code is disrupted in Hirschsprung disease
    Sumantra Chatterjee
    Kameko M. Karasaki
    Lauren E. Fries
    Ashish Kapoor
    Aravinda Chakravarti
    First Published November 15, 2021
  - Individualized VDJ recombination predisposes the available Ig sequence space
    Andrei Slabodkin
    Maria Chernigovskaya
    Ivana Mikocziova
    Rahmad Akbar
    Lonneke Scheffer
    Milena Pavlović Habib Bashour Igor Snapkov Brij Bhushan Mehta Cédric R. Weber Jose Gutierrez-Marcos Ludvig M. Sollid
    ...[+7 authors]...,
    Ingrid Hobæk Haff
    Geir Kjetil Sandve
    Philippe A. Robert
    Victor Greiff
    First Published November 23, 2021
  - Mutagenesis of human genomes by endogenous mobile elements on a population scale
    Nelson T. Chuang
    Eugene J. Gardner
    Diane M. Terry
    Jonathan Crabtree
    Anup A. Mahurkar
    First Published November 12, 2021
  - Alu insertion variants alter gene transcript levels
    Lindsay M. Payer
    Jared P. Steranka
    Maria S. Kryatova
    Giacomo Grillo
    Mathieu Lupien
    First Published November 19, 2021
  - Structural variants are a major source of gene expression differences in humans and often affect multiple nearby genes
    Alexandra J. Scott
    Colby Chiang
    Ira M. Hall
    First Published September 20, 2021
  - Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits
    Peter Orchard
    Nandini Manickam
    Christa Ventresca
    Swarooparani Vadlamudi
    Arushi Varshney
    Vivek Rai Jeremy Kaplan Claudia Lalancette
    ...[+3 authors]...,
    Karen L. Mohlke
    Katherine Gallagher
    Charles F. Burant
    Stephen C.J. Parker
    First Published November 23, 2021
  - Evolutionary rewiring of the wheat transcriptional regulatory network by lineage-specific transposable elements
    Yuyun Zhang
    Zijuan Li
    Yu'e Zhang
    Kande Lin
    Yuan Peng
    Luhuan Ye Yili Zhuang Meiyue Wang Yilin Xie Jingyu Guo Wan Teng Yiping Tong
    ...[+7 authors]...,
    Wenli Zhang
    Yongbiao Xue
    Zhaobo Lang
    Yijing Zhang
    First Published September 9, 2021
  - Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizophagus irregularis
    Alexandra Dallaire
    Bethan F. Manley
    Maya Wilkens
    Iliana Bista
    Clement Quan
    Edouard Evangelisti Charles R. Bradshaw Navin B. Ramakrishna
    ...[+3 authors]...,
    Sebastian Schornack
    Falk Butter
    Uta Paszkowski
    Eric A. Miska
    First Published November 12, 2021
  - Intergenic ORFs as elementary structural modules of de novo gene birth and protein evolution
    Chris Papadopoulos
    Isabelle Callebaut
    Jean-Christophe Gelly
    Isabelle Hatin
    Olivier Namy
    First Published November 22, 2021
  - Different trajectories of polyploidization shape the genomic landscape of the Brettanomyces bruxellensis yeast species
    Chris Eberlein
    Omar Abou Saada
    Anne Friedrich
    Warren Albertin
    Joseph Schacherer
    First Published November 23, 2021
Methods
- - Genome-wide cancer-specific chromatin accessibility patterns derived from archival processed xenograft tumors
    Shelsa S. Marcel
    Austin L. Quimby
    Melodie P. Noel
    Oscar C. Jaimes
    Marjan Mehrab-Mohseni
    Suud A. Ashur Brian Velasco James K. Tsuruta Sandeep K. Kasoji Charlene M. Santos
    ...[+5 authors]...,
    Paul A. Dayton
    Joel S. Parker
    Ian J. Davis
    Samantha G. Pattenden
    First Published November 23, 2021
  - Quantifying full-length circular RNAs in cancer
    Ken Hung-On Yu
    Christina Huan Shi
    Bo Wang
    Savio Ho-Chit Chow
    Grace Tin-Yun Chung
    Raymond Wai-Ming Lung Ke-En Tan
    ...[+2 authors]...,
    Yat-Yuen Lim
    Anna Chi-Man Tsang
    Kwok-Wai Lo
    Kevin Y. Yip
    First Published October 18, 2021
  - Global quantification exposes abundant low-level off-target activity by base editors
    Ilana Buchumenski
    Shalom Hillel Roth
    Eli Kopel
    Efrat Katsman
    Ariel Feiglin
    First Published October 19, 2021
Reviewer Index
- - Reviewer Index, Volume 31, 2021
    First Published December 2, 2021

Table of Contents

Volume 31, Issue 12 | December 2021

Research

Delayed DNA replication in haploid human embryonic stem cells

Decoding the function of bivalent chromatin in development and cancer

Epstein–Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci

A multi-enhancer RET regulatory code is disrupted in Hirschsprung disease

Individualized VDJ recombination predisposes the available Ig sequence space

Mutagenesis of human genomes by endogenous mobile elements on a population scale

Alu insertion variants alter gene transcript levels

Structural variants are a major source of gene expression differences in humans and often affect multiple nearby genes

Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits

Evolutionary rewiring of the wheat transcriptional regulatory network by lineage-specific transposable elements

Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizophagus irregularis

Intergenic ORFs as elementary structural modules of de novo gene birth and protein evolution

Different trajectories of polyploidization shape the genomic landscape of the Brettanomyces bruxellensis yeast species

Methods

Genome-wide cancer-specific chromatin accessibility patterns derived from archival processed xenograft tumors

Quantifying full-length circular RNAs in cancer

Global quantification exposes abundant low-level off-target activity by base editors

Reviewer Index

Reviewer Index, Volume 31, 2021

Table of Contents

Volume 31, Issue 12 | December 2021

Share this issue

Research

Methods

Reviewer Index