Volume 31, Issue 1 | January 2021

Review
- - Data structures based on k-mers for querying large collections of sequencing data sets
    Camille Marchet
    Christina Boucher
    Simon J. Puglisi
    Paul Medvedev
    Mikaël Salson
    First Published December 16, 2020
Research
- - Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis
    Kai Li
    Jiayue Xu
    Yanyun Luo
    Dingfeng Zou
    Ruiqin Han
    Shunshun Zhong Qing Zhao Xinyu Mang Mengzhen Li Yanmin Si Yan Lu Pengyu Li Cheng Jin Zhipeng Wang Fang Wang Shiying Miao Bo Wen
    ...[+12 authors]...,
    Linfang Wang
    Yanni Ma
    Jia Yu
    Wei Song
    First Published December 16, 2020
  - Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development
    Suba Rajendren
    Alfa Dhakal
    Pranathi Vadlamani
    Jack Townsend
    Sarah N. Deffit
    First Published December 18, 2020
  - Thermal stress accelerates Arabidopsis thaliana mutation rate
    Eric J. Belfield
    Carly Brown
    Zhong Jie Ding
    Lottie Chapman
    Mengqian Luo
    Eleanor Hinde Sam W. van Es Sophie Johnson
    ...[+3 authors]...,
    Youzheng Ning
    Shao Jian Zheng
    Aziz Mithani
    Nicholas P. Harberd
    First Published December 17, 2020
  - The origin and evolution of a distinct mechanism of transcription initiation in yeasts
    Zhaolian Lu
    Zhenguo Lin
    First Published November 20, 2020
  - Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules
    Jonathon L. Baker
    James T. Morton
    Márcia Dinis
    Ruth Alvarez
    Nini C. Tran
    First Published November 25, 2020
Methods
- - DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution
    Juniper J. Elacqua
    Navpreet Ranu
    Sarah E. DiIorio
    Paul C. Blainey
    First Published December 21, 2020
  - Transcript assembly improves expression quantification of transposable elements in single-cell RNA-seq data
    Wanqing Shao
    Ting Wang
    First Published December 21, 2020
  - Predictive modeling of single-cell DNA methylome data enhances integration with transcriptome data
    Yasin Uzun
    Hao Wu
    Kai Tan
    First Published November 20, 2020
  - Greater strength of selection and higher proportion of beneficial amino acid changing mutations in humans compared with mice and Drosophila melanogaster
    Ying Zhen
    Christian D. Huber
    Robert W. Davies
    Kirk E. Lohmueller
    First Published November 18, 2020
  - Generation of mouse conditional knockout alleles in one step using the i-GONAD method
    Renjie Shang
    Haifeng Zhang
    Pengpeng Bi
    First Published December 16, 2020
  - MAnorm2 for quantitatively comparing groups of ChIP-seq samples
    Shiqi Tu
    Mushan Li
    Haojie Chen
    Fengxiang Tan
    Jian Xu
    First Published November 18, 2020
Resources
- - Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders
    Guangsheng Pei
    Yin-Ying Wang
    Lukas M. Simon
    Yulin Dai
    Zhongming Zhao
    First Published December 3, 2020
  - Accessing NCBI data using the NCBI Sequence Viewer and Genome Data Viewer (GDV)
    Sanjida H. Rangwala
    Anatoliy Kuznetsov
    Victor Ananiev
    Andrea Asztalos
    Evgeny Borodin
    Vladislav Evgeniev Victor Joukov Vadim Lotov Ravinder Pannu
    ...[+4 authors]...,
    Dmitry Rudnev
    Andrew Shkeda
    Eric M. Weitz
    Valerie A. Schneider
    First Published November 25, 2020

Table of Contents

Volume 31, Issue 1 | January 2021

Review

Data structures based on k-mers for querying large collections of sequencing data sets

Research

Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis

Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development

Thermal stress accelerates Arabidopsis thaliana mutation rate

The origin and evolution of a distinct mechanism of transcription initiation in yeasts

Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules

Methods

DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution

Transcript assembly improves expression quantification of transposable elements in single-cell RNA-seq data

Predictive modeling of single-cell DNA methylome data enhances integration with transcriptome data

Greater strength of selection and higher proportion of beneficial amino acid changing mutations in humans compared with mice and Drosophila melanogaster

Generation of mouse conditional knockout alleles in one step using the i-GONAD method

MAnorm2 for quantitatively comparing groups of ChIP-seq samples

Resources

Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders

Accessing NCBI data using the NCBI Sequence Viewer and Genome Data Viewer (GDV)

Table of Contents

Volume 31, Issue 1 | January 2021

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Review

Research

Methods

Resources