Volume 27, Issue 1 | January 2017

Research
- - Reconstructing genetic history of Siberian and Northeastern European populations
    Emily H.M. Wong
    Andrey Khrunin
    Larissa Nichols
    Dmitry Pushkarev
    Denis Khokhrin
    Dmitry Verbenko Oleg Evgrafov
    ...[+2 authors]...,
    James Knowles
    John Novembre
    Svetlana Limborska
    Anton Valouev
    First Published December 13, 2016
  - Genome-wide uniformity of human ‘open’ pre-initiation complexes
    William K.M. Lai
    B. Franklin Pugh
    First Published November 10, 2016
  - Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs
    Marta Melé
    Kaia Mattioli
    William Mallard
    David M. Shechner
    Chiara Gerhardinger
    John L. Rinn
    First Published December 7, 2016
  - A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity
    Fumitaka Inoue
    Martin Kircher
    Beth Martin
    Gregory M. Cooper
    Daniela M. Witten
    Michael T. McManus
    Nadav Ahituv
    Jay Shendure
    First Published November 9, 2016
  - Evolutionary patterns of metazoan microRNAs reveal targeting principles in the let-7 and miR-10 families
    Justin M. Wolter
    Hoai Huang Thi Le
    Alexander Linse
    Victoria A. Godlove
    Thuy-Duyen Nguyen
    Kasuen Kotagama
    Alissa Lynch
    Alan Rawls
    Marco Mangone
    First Published December 7, 2016
  - Drosophila poised enhancers are generated during tissue patterning with the help of repression
    Nina Koenecke
    Jeff Johnston
    Qiye He
    Samuel Meier
    Julia Zeitlinger
    First Published November 14, 2016
  - Nucleosome fragility is associated with future transcriptional response to developmental cues and stress in C. elegans
    Tess E. Jeffers
    Jason D. Lieb
    First Published November 14, 2016
  - Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators
    David van Dijk
    Eilon Sharon
    Maya Lotan-Pompan
    Adina Weinberger
    Eran Segal
    Lucas B. Carey
    First Published December 13, 2016
  - A novel translational control mechanism involving RNA structures within coding sequences
    Jennifer Jungfleisch
    Danny D. Nedialkova
    Ivan Dotu
    Katherine E. Sloan
    Neus Martinez-Bosch
    Lukas Brüning Emanuele Raineri
    ...[+2 authors]...,
    Pilar Navarro
    Markus T. Bohnsack
    Sebastian A. Leidel
    Juana Díez
    First Published November 7, 2016
Methods
- - Identification of complex genomic rearrangements in cancers using CouGaR
    Misko Dzamba
    Arun K. Ramani
    Pawel Buczkowicz
    Yue Jiang
    Man Yu
    Cynthia Hawkins
    Michael Brudno
    First Published November 14, 2016
  - The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells
    Mireia Jordà
    Anna Díez-Villanueva
    Izaskun Mallona
    Berta Martín
    Sergi Lois
    Víctor Barrera
    Manel Esteller
    Tanya Vavouri
    Miguel A. Peinado
    First Published December 20, 2016
  - Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes
    T.S. Keshava Prasad
    Ajeet Kumar Mohanty
    Manish Kumar
    Sreelakshmi K. Sreenivasamurthy
    Gourav Dey
    Raja Sekhar Nirujogi Sneha M. Pinto Anil K. Madugundu Arun H. Patil Jayshree Advani Srikanth S. Manda Manoj Kumar Gupta Sutopa B. Dwivedi Dhanashree S. Kelkar Brantley Hall Xiaofang Jiang Ashley Peery Pavithra Rajagopalan Soujanya D. Yelamanchi Hitendra S. Solanki Remya Raja Gajanan J. Sathe Sandip Chavan Renu Verma Krishna M. Patel Ankit P. Jain Nazia Syed Keshava K. Datta Aafaque Ahmed Khan Manjunath Dammalli Savita Jayaram Aneesha Radhakrishnan Christopher J. Mitchell Chan-Hyun Na Nirbhay Kumar Photini Sinnis Igor V. Sharakhov Charles Wang
    ...[+33 authors]...,
    Harsha Gowda
    Zhijian Tu
    Ashwani Kumar
    Akhilesh Pandey
    First Published November 15, 2016
  - The dynamic landscape of fission yeast meiosis alternative-splice isoforms
    Zheng Kuang
    Jef D. Boeke
    Stefan Canzar
    First Published November 17, 2016
Resources
- - A reference data set of 5.4 million phased human variants validated by genetic inheritance from sequencing a three-generation 17-member pedigree
    Michael A. Eberle
    Epameinondas Fritzilas
    Peter Krusche
    Morten Källberg
    Benjamin L. Moore
    Mitchell A. Bekritsky Zamin Iqbal Han-Yu Chuang Sean J. Humphray Aaron L. Halpern
    ...[+5 authors]...,
    Semyon Kruglyak
    Elliott H. Margulies
    Gil McVean
    David R. Bentley
    First Published November 30, 2016
  - Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource
    Michael J. Keogh
    Wei Wei
    Ian Wilson
    Jon Coxhead
    Sarah Ryan
    Sara Rollinson Helen Griffin Marzena Kurzawa-Akanbi Mauro Santibanez-Koref Kevin Talbot Martin R. Turner Chris-Anne McKenzie Claire Troakes Johannes Attems Colin Smith Safa Al Sarraj Chris M. Morris
    ...[+12 authors]...,
    Olaf Ansorge
    Stuart Pickering-Brown
    James W. Ironside
    Patrick F. Chinnery
    First Published December 21, 2016

Table of Contents

Volume 27, Issue 1 | January 2017

Research

Reconstructing genetic history of Siberian and Northeastern European populations

Genome-wide uniformity of human ‘open’ pre-initiation complexes

Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs

A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity

Evolutionary patterns of metazoan microRNAs reveal targeting principles in the let-7 and miR-10 families

Drosophila poised enhancers are generated during tissue patterning with the help of repression

Nucleosome fragility is associated with future transcriptional response to developmental cues and stress in C. elegans

Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

A novel translational control mechanism involving RNA structures within coding sequences

Methods

Identification of complex genomic rearrangements in cancers using CouGaR

The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells

Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes

The dynamic landscape of fission yeast meiosis alternative-splice isoforms

Resources

A reference data set of 5.4 million phased human variants validated by genetic inheritance from sequencing a three-generation 17-member pedigree

Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource

Table of Contents

Volume 27, Issue 1 | January 2017

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Research

Methods

Resources