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Research

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  Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

  • Laura B. Ramsey,
  • Gitte H. Bruun,
  • Wenjian Yang,
  • Lisa R. Treviño,
  • Selina Vattathil,
  • Paul Scheet,
  • Cheng Cheng,
  • Gary L. Rosner,
  • Kathleen M. Giacomini,
  • Yiping Fan,
  • Alex Sparreboom,
  • Torben S. Mikkelsen,
  • Thomas J. Corydon,
  • Ching-Hon Pui,
  • William E. Evans,
  • and Mary V. Relling

  Genome Res. January 2012 22: 1-8; Published in Advance December 6, 2011, doi:10.1101/gr.129668.111
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  Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

  • Bum-Kyu Lee,
  • Akshay A. Bhinge,
  • Anna Battenhouse,
  • Ryan M. McDaniell,
  • Zheng Liu,
  • Lingyun Song,
  • Yunyun Ni,
  • Ewan Birney,
  • Jason D. Lieb,
  • Terrence S. Furey,
  • Gregory E. Crawford,
  • and Vishwanath R. Iyer

  Genome Res. January 2012 22: 9-24; Published in Advance November 16, 2011, doi:10.1101/gr.127597.111
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  Aberrant firing of replication origins potentially explains intragenic nonrecurrent rearrangements within genes, including the human DMD gene

  • Arunkanth Ankala,
  • Jordan N. Kohn,
  • Anisha Hegde,
  • Arjun Meka,
  • Chin Lip Hon Ephrem,
  • Syed H. Askree,
  • Shruti Bhide,
  • and Madhuri R. Hegde

  Genome Res. January 2012 22: 25-34; Published in Advance November 16, 2011, doi:10.1101/gr.123463.111
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  Changes in exon–intron structure during vertebrate evolution affect the splicing pattern of exons

  • Sahar Gelfman,
  • David Burstein,
  • Osnat Penn,
  • Anna Savchenko,
  • Maayan Amit,
  • Schraga Schwartz,
  • Tal Pupko,
  • and Gil Ast

  Genome Res. January 2012 22: 35-50; Published in Advance October 5, 2011, doi:10.1101/gr.119834.110
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  Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

  • Erik Axelsson,
  • Matthew T. Webster,
  • Abhirami Ratnakumar,
  • The LUPA Consortium,
  • Chris P. Ponting,
  • and Kerstin Lindblad-Toh

  Genome Res. January 2012 22: 51-63; Published in Advance October 17, 2011, doi:10.1101/gr.124123.111
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  Developmental control of gene copy number by repression of replication initiation and fork progression

  • Noa Sher,
  • George W. Bell,
  • Sharon Li,
  • Jared Nordman,
  • Thomas Eng,
  • Matthew L. Eaton,
  • David M. MacAlpine,
  • and Terry L. Orr-Weaver

  Genome Res. January 2012 22: 64-75; Published in Advance November 16, 2011, doi:10.1101/gr.126003.111
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  A novel candidate cis-regulatory motif pair in the promoters of germline and oogenesis genes in C. elegans

  • Chaim Linhart,
  • Yonit Halperin,
  • Amir Darom,
  • Shahar Kidron,
  • Limor Broday,
  • and Ron Shamir

  Genome Res. January 2012 22: 76-83; Published in Advance September 19, 2011, doi:10.1101/gr.115626.110
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  A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast

  • Judith B. Zaugg and
  • Nicholas M. Luscombe

  Genome Res. January 2012 22: 84-94; Published in Advance September 19, 2011, doi:10.1101/gr.124099.111
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  Contrasting patterns of evolution following whole genome versus tandem duplication events in Populus

  • Eli Rodgers-Melnick,
  • Shrinivasrao P. Mane,
  • Palitha Dharmawardhana,
  • Gancho T. Slavov,
  • Oswald R. Crasta,
  • Steven H. Strauss,
  • Amy M. Brunner,
  • and Stephen P. DiFazio

  Genome Res. January 2012 22: 95-105; Published in Advance October 5, 2011, doi:10.1101/gr.125146.111
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  Genomic basis of endosymbiont-conferred protection against an insect parasitoid

  • Allison K. Hansen,
  • Christoph Vorburger,
  • and Nancy A. Moran

  Genome Res. January 2012 22: 106-114; Published in Advance September 23, 2011, doi:10.1101/gr.125351.111
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  Microbial domestication signatures of Lactococcus lactis can be reproduced by experimental evolution

  • Herwig Bachmann,
  • Marjo J.C. Starrenburg,
  • Douwe Molenaar,
  • Michiel Kleerebezem,
  • and Johan E.T. van Hylckama Vlieg

  Genome Res. January 2012 22: 115-124; Published in Advance November 11, 2011, doi:10.1101/gr.121285.111
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