Volume 20, Issue 8 | August 2010

Research
- - Contrasting GC-content dynamics across 33 mammalian genomes: Relationship with life-history traits and chromosome sizes
    Jonathan Romiguier
    Vincent Ranwez
    Emmanuel J.P. Douzery
    Nicolas Galtier
    First Published June 7, 2010
  - Signatures of RNA binding proteins globally coupled to effective microRNA target sites
    Anders Jacobsen
    Jiayu Wen
    Debora S. Marks
    Anders Krogh
    First Published May 27, 2010
  - Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver
    Xia Yang
    Bin Zhang
    Cliona Molony
    Eugene Chudin
    Ke Hao
    Jun Zhu Andrea Gaedigk Christine Suver Hua Zhong J. Steven Leeder F. Peter Guengerich Stephen C. Strom Erin Schuetz Thomas H. Rushmore Roger G. Ulrich
    ...[+10 authors]...,
    J. Greg Slatter
    Eric E. Schadt
    Andrew Kasarskis
    Pek Yee Lum
    First Published June 10, 2010
  - Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver
    Brad G. Hoffman
    Gordon Robertson
    Bogard Zavaglia
    Mike Beach
    Rebecca Cullum
    Sam Lee Galina Soukhatcheva Leping Li Elizabeth D. Wederell Nina Thiessen Mikhail Bilenky Timothee Cezard Angela Tam Baljit Kamoh Inanc Birol Derek Dai YongJun Zhao Martin Hirst C. Bruce Verchere
    ...[+14 authors]...,
    Cheryl D. Helgason
    Marco A. Marra
    Steven J.M. Jones
    Pamela A. Hoodless
    First Published June 15, 2010
  - A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells
    Michael R. Tallack
    Tom Whitington
    Wai Shan Yuen
    Elanor N. Wainwright
    Janelle R. Keys
    Brooke B. Gardiner Ehsan Nourbakhsh
    ...[+2 authors]...,
    Nicole Cloonan
    Sean M. Grimmond
    Timothy L. Bailey
    Andrew C. Perkins
    First Published May 27, 2010
  - Genome-wide identification of TAL1's functional targets: Insights into its mechanisms of action in primary erythroid cells
    Mira T. Kassouf
    Jim R. Hughes
    Stephen Taylor
    Simon J. McGowan
    Shamit Soneji
    First Published June 21, 2010
  - Fragile regions and not functional constraints predominate in shaping gene organization in the genus Drosophila
    Marcin von Grotthuss
    Michael Ashburner
    José M. Ranz
    First Published July 2, 2010
  - Genome-wide misexpression of X-linked versus autosomal genes associated with hybrid male sterility
    Xuemei Lu
    Joshua A. Shapiro
    Chau-Ti Ting
    Yan Li
    Chunyan Li
    Jin Xu Huanwei Huang Ya-Jen Cheng Anthony J. Greenberg
    ...[+4 authors]...,
    Shou-Hsien Li
    Mao-Lien Wu
    Yang Shen
    Chung-I Wu
    First Published May 28, 2010
  - Natural selection shapes nucleotide polymorphism across the genome of the nematode Caenorhabditis briggsae
    Asher D. Cutter
    Jae Young Choi
    First Published May 27, 2010
  - Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts
    Ricardo DeMarco
    William Mathieson
    Sophia J. Manuel
    Gary P. Dillon
    Rachel S. Curwen
    Peter D. Ashton
    ...[+1 authors]...,
    Alasdair C. Ivens
    Matthew Berriman
    Sergio Verjovski-Almeida
    R. Alan Wilson
    First Published July 6, 2010
Method
- - A genome-wide map of human genetic interactions inferred from radiation hybrid genotypes
    Andy Lin
    Richard T. Wang
    Sangtae Ahn
    Christopher C. Park
    Desmond J. Smith
    First Published May 27, 2010
  - Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome
    Russell C. DeKelver
    Vivian M. Choi
    Erica A. Moehle
    David E. Paschon
    Dirk Hockemeyer
    Sebastiaan H. Meijsing Yasemin Sancak Xiaoxia Cui Eveline J. Steine Jeffrey C. Miller Phillip Tam Victor V. Bartsevich Xiangdong Meng Igor Rupniewski Sunita M. Gopalan Helena C. Sun Kathleen J. Pitz Jeremy M. Rock Lei Zhang Gregory D. Davis Edward J. Rebar Iain M. Cheeseman Keith R. Yamamoto
    ...[+18 authors]...,
    David M. Sabatini
    Rudolf Jaenisch
    Philip D. Gregory
    Fyodor D. Urnov
    First Published May 27, 2010
  - Predicting genetic modifier loci using functional gene networks
    Insuk Lee
    Ben Lehner
    Tanya Vavouri
    Junha Shin
    Andrew G. Fraser
    First Published June 9, 2010
Resource
- - Phenotypic annotation of the mouse X chromosome
    Brian J. Cox
    Marion Vollmer
    Owen Tamplin
    Mei Lu
    Steffen Biechele
    Marina Gertsenstein Claude van Campenhout Thomas Floss
    ...[+3 authors]...,
    Ralf Kühn
    Wolfgang Wurst
    Heiko Lickert
    Janet Rossant
    First Published June 14, 2010

Table of Contents

Volume 20, Issue 8 | August 2010

Research

Contrasting GC-content dynamics across 33 mammalian genomes: Relationship with life-history traits and chromosome sizes

Signatures of RNA binding proteins globally coupled to effective microRNA target sites

Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells

Genome-wide identification of TAL1's functional targets: Insights into its mechanisms of action in primary erythroid cells

Fragile regions and not functional constraints predominate in shaping gene organization in the genus Drosophila

Genome-wide misexpression of X-linked versus autosomal genes associated with hybrid male sterility

Natural selection shapes nucleotide polymorphism across the genome of the nematode Caenorhabditis briggsae

Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts

Method

A genome-wide map of human genetic interactions inferred from radiation hybrid genotypes

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

Predicting genetic modifier loci using functional gene networks

Resource

Phenotypic annotation of the mouse X chromosome

Table of Contents

Volume 20, Issue 8 | August 2010

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Research

Method

Resource