Volume 18, Issue 2 | February 2008

COMMENTARY
- - Confidence in comparative genomics
    Elliott H. Margulies
    First Published February 1, 2008
PERSPECTIVE
- - Qualifying the relationship between sequence conservation and molecular function
    Gregory M. Cooper
    Christopher D. Brown
    First Published February 1, 2008
LETTERS
- - Quantitative systems-level determinants of human genes targeted by successful drugs
    Lixia Yao
    Andrey Rzhetsky
    First Published December 14, 2007
  - Alternative approach to a heavy weight problem
    Amir Goren
    Eddo Kim
    Maayan Amit
    Ron Bochner
    Galit Lev-Maor
    First Published December 20, 2007
  - Gene number expansion and contraction in vertebrate genomes with respect to invertebrate genomes
    Anuphap Prachumwat
    Wen-Hsiung Li
    First Published December 14, 2007
  - Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription
    Zhuo Du
    Yiqiang Zhao
    Ning Li
    First Published December 20, 2007
  - Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions
    Elfar Torarinsson
    Zizhen Yao
    Eric D. Wiklund
    Jesper B. Bramsen
    Claus Hansen
    First Published December 20, 2007
  - Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b
    David M. McGaughey
    Ryan M. Vinton
    Jimmy Huynh
    Amr Al-Saif
    Michael A. Beer
    First Published December 10, 2007
  - Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast
    Heiko Schober
    Véronique Kalck
    Miguel A. Vega-Palas
    Griet Van Houwe
    Daniel Sage
    First Published December 20, 2007
  - Wolbachia genome integrated in an insect chromosome: Evolution and fate of laterally transferred endosymbiont genes
    Naruo Nikoh
    Kohjiro Tanaka
    Fukashi Shibata
    Natsuko Kondo
    Masahiro Hizume
    First Published December 11, 2007
  - Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum
    Tobias Mourier
    Celine Carret
    Sue Kyes
    Zoe Christodoulou
    Paul P. Gardner
    Daniel C. Jeffares Robert Pinches Bart Barrell Matt Berriman
    ...[+4 authors]...,
    Sam Griffiths-Jones
    Alasdair Ivens
    Chris Newbold
    Arnab Pain
    First Published December 20, 2007
  - A bacterial metapopulation adapts locally to phage predation despite global dispersal
    Victor Kunin
    Shaomei He
    Falk Warnecke
    S. Brook Peterson
    Hector Garcia Martin
    Matthew Haynes Natalia Ivanova Linda L. Blackall
    ...[+3 authors]...,
    Mya Breitbart
    Forest Rohwer
    Katherine D. McMahon
    Philip Hugenholtz
    First Published December 12, 2007
Methods
- - Uncertainty in homology inferences: Assessing and improving genomic sequence alignment
    Gerton Lunter
    Andrea Rocco
    Naila Mimouni
    Andreas Heger
    Alexandre Caldeira
    First Published December 11, 2007
  - Generic eukaryotic core promoter prediction using structural features of DNA
    Thomas Abeel
    Yvan Saeys
    Eric Bonnet
    Pierre Rouzé
    Yves Van de Peer
    First Published December 20, 2007
  - Short read fragment assembly of bacterial genomes
    Mark J. Chaisson
    Pavel A. Pevzner
    First Published December 14, 2007
  - Resolving the structural features of genomic islands: A machine learning approach
    Georgios S. Vernikos
    Julian Parkhill
    First Published December 10, 2007

Table of Contents

Volume 18, Issue 2 | February 2008

COMMENTARY

Confidence in comparative genomics

PERSPECTIVE

Qualifying the relationship between sequence conservation and molecular function

LETTERS

Quantitative systems-level determinants of human genes targeted by successful drugs

Alternative approach to a heavy weight problem

Gene number expansion and contraction in vertebrate genomes with respect to invertebrate genomes

Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription

Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions

Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b

Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast

Wolbachia genome integrated in an insect chromosome: Evolution and fate of laterally transferred endosymbiont genes

Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum

A bacterial metapopulation adapts locally to phage predation despite global dispersal

Methods

Uncertainty in homology inferences: Assessing and improving genomic sequence alignment

Generic eukaryotic core promoter prediction using structural features of DNA

Short read fragment assembly of bacterial genomes

Resolving the structural features of genomic islands: A machine learning approach

Table of Contents

Volume 18, Issue 2 | February 2008

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COMMENTARY

PERSPECTIVE

LETTERS

Methods