Volume 10, Issue 12 | December 2000

INSIGHT/OUTLOOK
- - Keeping the Serpin Machine Running Smoothly
    Peter G.W. Gettins
    First Published December 1, 2000
  - Tools for the Population Genomics of the Tubercle Bacilli
    Alexander S. Pym
    Roland Brosch
    First Published December 1, 2000
  - Doubling the Rewards: Testis ESTs for Drosophila Gene Discovery and Spermatogenesis Expression Profile Analysis
    Barbara T. Wakimoto
    First Published December 1, 2000
ARTICLES
- - Phylogeny of the Serpin Superfamily: Implications of Patterns of Amino Acid Conservation for Structure and Function
    James A. Irving
    Robert N. Pike
    Arthur M. Lesk
    James C. Whisstock
    First Published November 21, 2000
  - Fine-Resolution Physical Mapping of Genomic Diversity in Candida albicans
    Hiroji Chibana
    Janna L. Beckerman
    P.T. Magee
    First Published December 1, 2000
  - Comparative Genome Analysis of the Mouse Imprinted Gene Impact and Its Nonimprinted Human Homolog IMPACT: Toward the Structural Basis for Species-Specific Imprinting
    Kohji Okamura
    Yuriko Hagiwara-Takeuchi
    Tao Li
    Thanh H. Vu
    Momoki Hirai
    First Published December 1, 2000
  - Zebrafish Comparative Genomics and the Origins of Vertebrate Chromosomes
    John H. Postlethwait
    Ian G. Woods
    Phuong Ngo-Hazelett
    Yi-Lin Yan
    Peter D. Kelly
    First Published December 1, 2000
LETTERS
- - A Comparative Map of the Zebrafish Genome
    Ian G. Woods
    Peter D. Kelly
    Felicia Chu
    Phuong Ngo-Hazelett
    Yi-Lin Yan
    First Published December 1, 2000
  - Identification, Characterization, and Mapping of Expressed Sequence Tags from an Embryonic Zebrafish Heart cDNA Library
    Christopher Ton
    David M. Hwang
    Adam A. Dempsey
    Hong-Chang Tang
    Jennifer Yoon
    First Published December 1, 2000
  - The Mouse Clock Locus: Sequence and Comparative Analysis of 204 Kb from Mouse Chromosome 5
    Lisa D. Wilsbacher
    Ashvin M. Sangoram
    Marina P. Antoch
    Joseph S. Takahashi
    First Published December 1, 2000
  - Single QTL Effects, Epistasis, and Pleiotropy Account for Two-thirds of the Phenotypic F2 Variance of Growth and Obesity in DU6i x DBA/2 Mice
    Gudrun A. Brockmann
    Jürgen Kratzsch
    Chris S. Haley
    Ulla Renne
    Manfred Schwerin
    First Published November 21, 2000
  - Sequence Diversity and Genomic Organization of Vomeronasal Receptor Genes in the Mouse
    Karina Del Punta
    Andrea Rothman
    Ivan Rodriguez
    Peter Mombaerts
    First Published December 1, 2000
  - MHC-Linked Olfactory Receptor Loci Exhibit Polymorphism and Contribute to Extended HLA/OR-Haplotypes
    Anke Ehlers
    Stephan Beck
    Simon A. Forbes
    John Trowsdale
    Armin Volz
    First Published December 1, 2000
  - Characterization of Nonfunctional V1R-like Pheromone Receptor Sequences in Human
    Dominique Giorgi
    Cynthia Friedman
    Barbara J. Trask
    Sylvie Rouquier
    First Published December 1, 2000
  - Assessment of Compositional Heterogeneity Within and Between Eukaryotic Genomes
    Anton Nekrutenko
    Wen-Hsiung Li
    First Published December 1, 2000
  - A Random Sequencing Approach for the Analysis of the Trypanosoma cruzi Genome: General Structure, Large Gene and Repetitive DNA Families, and Gene Discovery
    Fernán Agüero
    Ramiro E. Verdún
    Alberto Carlos C. Frasch
    Daniel O. Sánchez
    First Published November 21, 2000
  - The Mouse Brain Transcriptome by SAGE: Differences in Gene Expression between P30 Brains of the Partial Trisomy 16 Mouse Model of Down Syndrome (Ts65Dn) and Normals
    Roman Chrast
    Hamish S. Scott
    Marie Pierre Papasavvas
    Colette Rossier
    Emmanuel S. Antonarakis
    Christine Barras Muriel T. Davisson Cecilia Schmidt
    ...[+3 authors]...,
    Xavier Estivill
    Mara Dierssen
    Melanie Pritchard
    Stylianos E. Antonarakis
    First Published December 1, 2000
  - Microarray Expression Profiling Identifies Genes with Altered Expression in HDL-Deficient Mice
    Matthew J. Callow
    Sandrine Dudoit
    Elaine L. Gong
    Terence P. Speed
    Edward M. Rubin
    First Published December 1, 2000
  - Gene Discovery Using Computational and Microarray Analysis of Transcription in the Drosophila melanogaster Testis
    Justen Andrews
    Gerard G. Bouffard
    Chris Cheadle
    Jining Lü
    Kevin G. Becker
    First Published December 1, 2000
METHODS
- - Detection of Deleted Genomic DNA Using a Semiautomated Computational Analysis of GeneChip Data
    Hugh Salamon
    Midori Kato-Maeda
    Peter M. Small
    Jorg Drenkow
    Thomas R. Gingeras
    First Published November 21, 2000
  - The Comparison of Gene Expression from Multiple cDNA Libraries
    Dov J Stekel
    Yoav Git
    Francesco Falciani
    First Published November 21, 2000
RESOURCE
- - A Large Database of Chicken Bursal ESTs as a Resource for the Analysis of Vertebrate Gene Function
    Igor Abdrakhmanov
    Dmitry Lodygin
    Paul Geroth
    Hiroshi Arakawa
    Andy Law
    First Published December 1, 2000

Table of Contents

Volume 10, Issue 12 | December 2000

INSIGHT/OUTLOOK

Keeping the Serpin Machine Running Smoothly

Tools for the Population Genomics of the Tubercle Bacilli

Doubling the Rewards: Testis ESTs for Drosophila Gene Discovery and Spermatogenesis Expression Profile Analysis

ARTICLES

Phylogeny of the Serpin Superfamily: Implications of Patterns of Amino Acid Conservation for Structure and Function

Fine-Resolution Physical Mapping of Genomic Diversity in Candida albicans

Comparative Genome Analysis of the Mouse Imprinted Gene Impact and Its Nonimprinted Human Homolog IMPACT: Toward the Structural Basis for Species-Specific Imprinting

Zebrafish Comparative Genomics and the Origins of Vertebrate Chromosomes

LETTERS

A Comparative Map of the Zebrafish Genome

Identification, Characterization, and Mapping of Expressed Sequence Tags from an Embryonic Zebrafish Heart cDNA Library

The Mouse Clock Locus: Sequence and Comparative Analysis of 204 Kb from Mouse Chromosome 5

Single QTL Effects, Epistasis, and Pleiotropy Account for Two-thirds of the Phenotypic F2 Variance of Growth and Obesity in DU6i x DBA/2 Mice

Sequence Diversity and Genomic Organization of Vomeronasal Receptor Genes in the Mouse

MHC-Linked Olfactory Receptor Loci Exhibit Polymorphism and Contribute to Extended HLA/OR-Haplotypes

Characterization of Nonfunctional V1R-like Pheromone Receptor Sequences in Human

Assessment of Compositional Heterogeneity Within and Between Eukaryotic Genomes

A Random Sequencing Approach for the Analysis of the Trypanosoma cruzi Genome: General Structure, Large Gene and Repetitive DNA Families, and Gene Discovery

The Mouse Brain Transcriptome by SAGE: Differences in Gene Expression between P30 Brains of the Partial Trisomy 16 Mouse Model of Down Syndrome (Ts65Dn) and Normals

Microarray Expression Profiling Identifies Genes with Altered Expression in HDL-Deficient Mice

Gene Discovery Using Computational and Microarray Analysis of Transcription in the Drosophila melanogaster Testis

METHODS

Detection of Deleted Genomic DNA Using a Semiautomated Computational Analysis of GeneChip Data

The Comparison of Gene Expression from Multiple cDNA Libraries

RESOURCE

A Large Database of Chicken Bursal ESTs as a Resource for the Analysis of Vertebrate Gene Function

Table of Contents

Volume 10, Issue 12 | December 2000

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INSIGHT/OUTLOOK

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LETTERS

METHODS

RESOURCE