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Research

The human gut virome: Inter-individual variation and dynamic response to diet

  • First Published August 31, 2011
Method

Efficient cross-species capture hybridization and next-generation sequencing of mitochondrial genomes from noninvasively sampled museum specimens

  • First Published August 31, 2011
Review

What fraction of the human genome is functional?

  • First Published August 29, 2011
Method

Discriminative prediction of mammalian enhancers from DNA sequence

  • First Published August 29, 2011
Research

Epigenetic regulation of normal human mammary cell type–specific miRNAs

  • First Published August 26, 2011
Method

A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data

  • First Published August 26, 2011
Research

Delineation of key regulatory elements identifies points of vulnerability in the mitogen-activated signaling network

  • First Published August 24, 2011
Research

Relating CNVs to transcriptome data at fine resolution: Assessment of the effect of variant size, type, and overlap with functional regions

  • First Published August 23, 2011
Resource

Macaca fascicularis as a model for drug safety assessment" > Genome-based analysis of the nonhuman primate Macaca fascicularis as a model for drug safety assessment

  • First Published August 23, 2011
Research

DNA methylation profiles of human active and inactive X chromosomes

  • First Published August 23, 2011
Method

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors

  • First Published August 18, 2011
Research

Analysis of alternative splicing associated with aging and neurodegeneration in the human brain

  • First Published August 16, 2011
Research

Genetic variation in radiation-induced cell death

  • First Published August 15, 2011
Method

Digital gene expression for non-model organisms

  • First Published August 15, 2011
Method

Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases

  • First Published August 15, 2011
Research

Copy number variation analysis in the great apes reveals species-specific patterns of structural variation

  • First Published August 8, 2011
Resource

The Proteome Folding Project: Proteome-scale prediction of structure and function

  • First Published August 8, 2011
Resource

Synthetic spike-in standards for RNA-seq experiments

  • First Published August 4, 2011
Method

A comprehensively molecular haplotype-resolved genome of a European individual

  • First Published August 3, 2011
Research

Genome-wide depletion of replication initiation events in highly transcribed regions

  • First Published August 3, 2011
Research

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

  • First Published August 3, 2011
Research

Transcriptome dynamics through alternative polyadenylation in developmental and environmental responses in plants revealed by deep sequencing

  • First Published August 3, 2011
Research

Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatin

  • First Published July 29, 2011
Method

True single-molecule DNA sequencing of a pleistocene horse bone

  • First Published July 29, 2011
Research

Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1

  • First Published July 27, 2011
Method

Trans genomic capture and sequencing of primate exomes reveals new targets of positive selection" > Trans genomic capture and sequencing of primate exomes reveals new targets of positive selection

  • First Published July 27, 2011
Research

Anopheles gambiae using high-resolution Fourier transform mass spectrometry" > A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry

  • First Published July 27, 2011
Research

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

  • First Published July 27, 2011
Method

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases

  • First Published July 27, 2011
Research

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer

  • First Published July 25, 2011
Resource

Genome-scale phylogenetic function annotation of large and diverse protein families

  • First Published July 22, 2011
Research

Coevolution of retroelements and tandem zinc finger genes

  • First Published July 22, 2011
Research

Large-scale methylation domains mark a functional subset of neuronally expressed genes

  • First Published July 22, 2011
Method

Accurate and comprehensive sequencing of personal genomes

  • First Published July 19, 2011
Method

BRCA1 mutations" > Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations

  • First Published July 15, 2011
Research

Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication

  • First Published July 14, 2011
Method

Application of microdroplet PCR for large-scale targeted bisulfite sequencing

  • First Published July 14, 2011
Research

Assessment of palindromes as platforms for DNA amplification in breast cancer

  • First Published July 13, 2011
Research

Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

  • First Published July 12, 2011
Method

Barcoding bias in high-throughput multiplex sequencing of miRNA

  • First Published July 12, 2011
Research

Parallel evolution of transcriptome architecture during genome reorganization

  • First Published July 12, 2011
Research

Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes

  • First Published July 12, 2011
Resource

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

  • First Published July 12, 2011
Research

Variety of genomic DNA patterns for nucleosome positioning

  • First Published July 12, 2011
Research

Loss of exon identity is a common mechanism of human inherited disease

  • First Published July 12, 2011
Research

Genetic analysis in the Collaborative Cross breeding population

  • First Published July 6, 2011
Erratum

Erratum

  • First Published July 1, 2011
Research

Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

  • First Published July 1, 2011
Research

Extensive relationship between antisense transcription and alternative splicing in the human genome

  • First Published June 30, 2011
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