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Method

Model-driven mapping of transcriptional networks reveals the circuitry and dynamics of virulence regulation

  • First Published February 2, 2015
Research

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

  • First Published February 2, 2015
Research

Actionable exomic incidental findings in 6503 participants: challenges of variant classification

  • First Published January 30, 2015
Research

A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation

  • First Published January 22, 2015
Research

Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription

  • First Published January 21, 2015
Resource

lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines" > A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines

  • First Published January 15, 2015
Resource

Drosophila melanogaster genome" > The Release 6 reference sequence of the Drosophila melanogaster genome

  • First Published January 14, 2015
Method

Single-cell-level spatial gene expression in the embryonic neural differentiation niche

  • First Published January 9, 2015
Research

Drosophila wing development" > A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development

  • First Published January 7, 2015
Resource

Genome-wide discovery of human splicing branchpoints

  • First Published January 5, 2015
Research

BRF1 mutations alter RNA polymerase III–dependent transcription and cause neurodevelopmental anomalies" > BRF1 mutations alter RNA polymerase III–dependent transcription and cause neurodevelopmental anomalies

  • First Published January 5, 2015
Research

RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts

  • First Published December 18, 2014
Research

Candida albicans" > Genetic and phenotypic intra-species variation in Candida albicans

  • First Published December 11, 2014
Research

Staphylococcus aureus in a high transmission setting" > Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting

  • First Published December 9, 2014
Research

Asymmetric nucleosomes flank promoters in the budding yeast genome

  • First Published December 9, 2014
Research

Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline

  • First Published December 5, 2014
Research

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

  • First Published December 1, 2014
Author Index

Author Index, Volume 24, 2014

  • First Published December 1, 2014
Reviewer Index

Reviewer Index, Volume 24, 2014

  • First Published December 1, 2014
Research

Arabidopsis reveals features and regulation of siRNA biogenesis" > Detection of Pol IV/RDR2-dependent transcripts at the genomic scale in Arabidopsis reveals features and regulation of siRNA biogenesis

  • First Published November 20, 2014
Research

Decoupling of evolutionary changes in transcription factor binding and gene expression in mammals

  • First Published November 13, 2014
Research

TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity

  • First Published November 12, 2014
Method

The discovery of integrated gene networks for autism and related disorders

  • First Published November 5, 2014
Method

Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks

  • First Published November 5, 2014
Research

Escherichia coli strains" > Large-scale genomic sequencing of extraintestinal pathogenic Escherichia coli strains

  • First Published November 4, 2014
Research

Genome accessibility is widely preserved and locally modulated during mitosis

  • First Published November 4, 2014
Resource

Single haplotype assembly of the human genome from a hydatidiform mole

  • First Published November 4, 2014
Method

Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line

  • First Published November 4, 2014
Research

Large transcription units unify copy number variants and common fragile sites arising under replication stress

  • First Published November 4, 2014
Research

C. elegans and ADAR mutants" > Profiling the RNA editomes of wild-type C. elegans and ADAR mutants

  • First Published November 4, 2014
Research

Arabidopsis thaliana" > Genome-wide analysis of local chromatin packing in Arabidopsis thaliana

  • First Published November 3, 2014
Research

Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes

  • First Published November 3, 2014
Research

Two new insulator proteins, Pita and ZIPIC, target CP190 to chromatin

  • First Published October 23, 2014
Research

Neurospora: the role of mutational bias and selection" > Intron evolution in Neurospora: the role of mutational bias and selection

  • First Published October 23, 2014
Method

In vitro, long-range sequence information for de novo genome assembly via transposase contiguity

  • First Published October 19, 2014
Research

Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis

  • First Published October 15, 2014
Research

Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis

  • First Published October 15, 2014
Research

Widespread contribution of transposable elements to the innovation of gene regulatory networks

  • First Published October 15, 2014
Research

Arabidopsis thaliana mutations and epimutations" > Environmentally responsive genome-wide accumulation of de novo Arabidopsis thaliana mutations and epimutations

  • First Published October 14, 2014
Research

Estimating genotype error rates from high-coverage next-generation sequence data

  • First Published October 10, 2014
Method

Application of histone modification-specific interaction domains as an alternative to antibodies

  • First Published October 9, 2014
Research

Accounting for biases in riboprofiling data indicates a major role for proline in stalling translation

  • First Published October 7, 2014
Research

Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

  • First Published October 7, 2014
Research

Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters

  • First Published October 7, 2014
Method

Parente2: a fast and accurate method for detecting identity by descent

  • First Published October 1, 2014
Research

Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity" > Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity

  • First Published October 1, 2014
Resource

Alignathon: a competitive assessment of whole-genome alignment methods

  • First Published October 1, 2014
Research

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

  • First Published September 30, 2014
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