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Research

Neisseria meningitidis" > The effect of recombination on the evolution of a population of Neisseria meningitidis

  • First Published June 9, 2021
Method

Rapid and accurate alignment of nucleotide conversion sequencing reads with HISAT-3N

  • First Published June 8, 2021
Research

A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes

  • First Published June 4, 2021
Method

A machine learning method for the discovery of minimum marker gene combinations for cell type identification from single-cell RNA sequencing

  • First Published June 4, 2021
Research

Arabidopsis" > Polycomb-dependent differential chromatin compartmentalization determines gene coregulation in Arabidopsis

  • First Published June 3, 2021
Research

Conserved noncoding sequences provide insights into regulatory sequence and loss of gene expression in maize

  • First Published May 27, 2021
Method

A joint deep learning model enables simultaneous batch effect correction, denoising, and clustering in single-cell transcriptomics

  • First Published May 25, 2021
Method

Characterizing spatial gene expression heterogeneity in spatially resolved single-cell transcriptomic data with nonuniform cellular densities

  • First Published May 25, 2021
Resource

Drosophila brain on cocaine at single-cell resolution" > The Drosophila brain on cocaine at single-cell resolution

  • First Published May 25, 2021
Method

Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories

  • First Published May 19, 2021
Research

Positive selective sweeps of epigenetic mutations regulating specialized metabolites in plants

  • First Published May 18, 2021
Research

CTCF looping is established during gastrulation in medaka embryos

  • First Published May 18, 2021
Research

Chromatin architecture transitions from zebrafish sperm through early embryogenesis

  • First Published May 18, 2021
Research

Distinct roles for RSC and SWI/SNF chromatin remodelers in genomic excision repair

  • First Published May 17, 2021
Research

Competition for DNA binding between paralogous transcription factors determines their genomic occupancy and regulatory functions

  • First Published May 11, 2021
Research

Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy

  • First Published May 7, 2021
Research

The genomic basis of evolutionary differentiation among honey bees

  • First Published May 4, 2021
Erratum

Erratum: Ultralow-input single-tube linked-read library method enables short-read second-generation sequencing systems to routinely generate highly accurate and economical long-range sequencing information

  • First Published May 3, 2021
Research

Toxoplasma gondii and related tissue coccidia" > A novel fragmented mitochondrial genome in the protist pathogen Toxoplasma gondii and related tissue coccidia

  • First Published April 27, 2021
Research

Linking the dynamics of chromatin occupancy and transcription with predictive models

  • First Published April 23, 2021
Resource

Caenorhabditis elegans nematodes" > Comprehensive characterization of tissue-specific chromatin accessibility in L2 Caenorhabditis elegans nematodes

  • First Published April 22, 2021
Resource

Modeling transcriptional regulation of model species with deep learning

  • First Published April 22, 2021
Research

Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

  • First Published April 20, 2021
Research

Enterprise, a massive transposon carrying Spok meiotic drive genes" > The Enterprise, a massive transposon carrying Spok meiotic drive genes

  • First Published April 19, 2021
Research

Xenopus laevis" > Identification and characterization of centromeric sequences in Xenopus laevis

  • First Published April 19, 2021
Method

Systematic evaluation of the effect of polyadenylation signal variants on the expression of disease-associated genes

  • First Published April 19, 2021
Research

Genome-wide analysis of plant miRNA action clarifies levels of regulatory dynamics across developmental contexts

  • First Published April 16, 2021
Research

The contributions from the progenitor genomes of the mesopolyploid Brassiceae are evolutionarily distinct but functionally compatible

  • First Published April 16, 2021
Research

Copy number variation underlies complex phenotypes in domestic dog breeds and other canids

  • First Published April 16, 2021
Research

Tissue-specific reprogramming of host tRNA transcriptome by the microbiome

  • First Published April 15, 2021
Research

Drosophila fat body is infection-specific" > The mode of expression divergence in Drosophila fat body is infection-specific

  • First Published April 15, 2021
Method

Profiling single-cell histone modifications using indexing chromatin immunocleavage sequencing

  • First Published April 14, 2021
Method

Mapping the regulatory landscape of auditory hair cells from single-cell multi-omics data

  • First Published April 9, 2021
Method

Bayesian estimation of cell type–specific gene expression with prior derived from single-cell data

  • First Published April 9, 2021
Method

Automated quality control and cell identification of droplet-based single-cell data using dropkick

  • First Published April 9, 2021
Method

Interpretation of allele-specific chromatin accessibility using cell state–aware deep learning

  • First Published April 8, 2021
Resource

Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring

  • First Published April 8, 2021
Method

Optimized sample selection for cost-efficient long-read population sequencing

  • First Published April 2, 2021
Research

Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

  • First Published April 2, 2021
Research

Antisense RNAs during early vertebrate development are divided in groups with distinct features

  • First Published April 1, 2021
Method

A HIT-trapping strategy for rapid generation of reversible and conditional alleles using a universal donor

  • First Published April 1, 2021
Corrigendum

Corrigendum: Benchmark and integration of resources for the estimation of human transcription factor activities

  • First Published April 1, 2021
Method

Alignment of single-cell RNA-seq samples without overcorrection using kernel density matching

  • First Published March 19, 2021
Method

Ultrafast functional profiling of RNA-seq data for nonmodel organisms

  • First Published March 17, 2021
Method

Correcting signal biases and detecting regulatory elements in STARR-seq data

  • First Published March 15, 2021
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