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Research

MEIS1 in conferring sleep abnormalities and impaired cerebellar development" > Cross-species variant-to-function analyses implicate MEIS1 in conferring sleep abnormalities and impaired cerebellar development

  • First Published July 30, 2026
Research

Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments

  • First Published July 30, 2026
Method

Fast and memory efficient partial order alignment with minipoa

  • First Published July 24, 2026
Method

Knowledge-driven interpretable neural networks for mechanistic insight

  • First Published July 24, 2026
In memoriam

Jim Watson (1928–2025): a genomics visionary

  • First Published July 23, 2026
Method

Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks

  • First Published July 22, 2026
Method

Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI

  • First Published July 22, 2026
Research

Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer

  • First Published July 17, 2026
Research

Methylation variability and LINE-1 transcriptional activation in multiple myeloma

  • First Published July 17, 2026
Method

ComicGTN infers disease-associated rare cell states from single-cell multiomic data using DNA sequence–augmented graph transformer networks

  • First Published July 17, 2026
Research

Genome-wide crossover analysis in the holocentric pantry moth reveals strong crossover assurance and interference during spermatogenesis

  • First Published July 16, 2026
Research

The impact of sex, age, and genetic ancestry on DNA methylation across tissues

  • First Published July 14, 2026
Method

A sequence-based classifier distinguishes phenotype-associated genes from other gene models in plants

  • First Published July 14, 2026
Research

An RNA polymerase III tissue and tumor atlas uncovers context-specific activities linked to 3D epigenome regulatory mechanisms

  • First Published July 13, 2026
Method

Biobank-scale genotype similarity search and dynamic patient-matched cohort creation with GenoSiS

  • First Published July 10, 2026
Method

De novo structural variants in autism spectrum disorder disrupt distal regulatory interactions of neuronal genes

  • First Published July 8, 2026
Resource

Dietary effects on cytosolic and mitochondrial tRNA abundance and modification patterns across mouse tissues

  • First Published July 8, 2026
Research

Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma

  • First Published July 8, 2026
Corrigendum

Corrigendum: Evaluation of strategies for evidence-driven genome annotation using long-read RNA-seq

  • First Published July 7, 2026
Corrigendum

Corrigendum: Characterizing cytosine methylation of polymorphic transposable element insertions using the human pangenome resources

  • First Published July 7, 2026
Corrigendum

Corrigendum: Systematic evaluation of the effect of polyadenylation signal variants on the expression of disease-associated genes

  • First Published July 7, 2026
Method

High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV

  • First Published July 6, 2026
Resource

Complete sequencing of medaka genomes reveals the architecture of centromeric satellites, giant mobile elements, and sex chromosomes

  • First Published July 1, 2026
Research

Convergence and conflict among telomere specialized transposons across 60 million years of Drosophilid evolution

  • First Published July 1, 2026
Research

Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture

  • First Published June 29, 2026
Method

A unified analysis of cell-type- and trajectory-associated pathways in single-cell data using Phoenix

  • First Published June 29, 2026
Research

Resf1 is required for proper placental development and configuration of trophoblast cell–specific heterochromatin" > Resf1 is required for proper placental development and configuration of trophoblast cell–specific heterochromatin

  • First Published June 29, 2026
Method

Locations of consecutive G•C base pairs direct genomic nucleosome positioning

  • First Published June 25, 2026
Research

Spatially resolved profiling of steroid nuclear receptors reveals a role for the disordered N-terminal domains in genome targeting and AP-1 interaction

  • First Published June 22, 2026
Perspective

The Topological Regulatory Logic of noncoding RNA–mediated gene expression

  • First Published June 17, 2026
Method

Flexible and scalable inference of spatially varying correlation in spatial transcriptomics with spCorr

  • First Published June 17, 2026
Research

Covariation of genetic and epigenetic divergence in barn swallows

  • First Published June 16, 2026
Resource

Tracing genome size dynamics in sharks and rays with inclusive sequence analysis by the Squalomix Consortium

  • First Published June 16, 2026
Method

MAPLE enables ultrasensitive detection of low-frequency cfDNA methylation haplotypes using short capture probes with cost-efficient performance

  • First Published June 16, 2026
Research

Cyanophora paradoxa reveals unique repair signature" > Elevated DNA insertion rate in Cyanophora paradoxa reveals unique repair signature

  • First Published June 12, 2026
Method

A comparison of ancient DNA yields across ossicles and the petrous bone reveals the best preservation in the stapes and incus

  • First Published June 11, 2026
Research

Evolution of an adaptive, inducible defensive trait in a model crustacean

  • First Published June 5, 2026
Method

Reference-informed spatial domain detection using weak supervision for spatial transcriptomics

  • First Published June 3, 2026
Method

Transfer learning enhances clinical utility of polygenic scores with small, phenotypically refined cohorts

  • First Published June 2, 2026
Research

Genome evolution in parthenogenetic nematodes shaped by chromosome rearrangements and introgression

  • First Published May 29, 2026
Method

Augmenting transcriptome annotations through the lens of splicing evolution

  • First Published May 29, 2026
Research

Transposable element small RNAs and large RNAs in aging brains and implications in Huntington's and Parkinson's disease

  • First Published May 28, 2026
Research

Whole-genome variant detection in long-read sequencing data from ultralow input patient samples

  • First Published May 28, 2026
Resource

A comprehensive single-cell atlas of monoallelic expression across various tissues in zebrafish

  • First Published May 28, 2026
Method

RECOMBINE identifies recurrent composite markers of cell types and states

  • First Published May 20, 2026
Research

Interplay between purging and admixture shapes genetic load in an invasive guppy population

  • First Published May 20, 2026
Research

Herbaria provide a valuable resource for obtaining informative mRNA

  • First Published May 19, 2026
Method

Deep learning the TF regulatory code for gene expression

  • First Published May 15, 2026
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