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PERSPECTIVE

Genome annotation past, present, and future: How to define an ORF at each locus

  • First Published December 8, 2005
Dog Special/Letters

Hotspots of mutation and breakage in dog and human chromosomes

  • First Published December 8, 2005
PERSPECTIVE

Xenomics

  • First Published December 8, 2005
PERSPECTIVE

Changing perspectives in yeast research nearly a decade after the genome sequence

  • First Published December 8, 2005
PERSPECTIVE

Ciona intestinalis" > Unraveling genomic regulatory networks in the simple chordate, Ciona intestinalis

  • First Published December 8, 2005
PERSPECTIVE

Grains of knowledge: Genomics of model cereals

  • First Published December 8, 2005
PERSPECTIVE

The mouse genome

  • First Published December 8, 2005
Dog Special/Resources

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

  • First Published December 8, 2005
Dog Special/Letters

Short interspersed elements (SINEs) are a major source of canine genomic diversity

  • First Published December 8, 2005
PERSPECTIVE

The canine genome

  • First Published December 8, 2005
Preface

Genome Research celebrated" > A decade of Genome Research celebrated

  • First Published December 8, 2005
PERSPECTIVE

Advances in livestock genomics: Opening the barn door

  • First Published December 8, 2005
PERSPECTIVE

Fish genomics and biology

  • First Published December 8, 2005
Dog Special/Letters

Selective sweep mapping of genes with large phenotypic effects

  • First Published December 8, 2005
PERSPECTIVE

Comparing the human and chimpanzee genomes: Searching for needles in a haystack

  • First Published December 8, 2005
PERSPECTIVE

Insights on biology and evolution from microbial genome sequencing

  • First Published December 8, 2005
PERSPECTIVE

Genomics of the fungal kingdom: Insights into eukaryotic biology

  • First Published December 8, 2005
Dog Special/Letters

Interaction between the X chromosome and an autosome regulates size sexual dimorphism in Portuguese Water Dogs

  • First Published December 8, 2005
PERSPECTIVE

Chicken genome: Current status and future opportunities

  • First Published December 8, 2005
PERSPECTIVE

Genomics of the future: Identification of quantitative trait loci in the mouse

  • First Published December 8, 2005
Dog Special/Letters

Genetics of canid skeletal variation: Size and shape of the pelvis

  • First Published December 8, 2005
PERSPECTIVE

C. elegans: So many genes, such a little worm" > Genomics in C. elegans: So many genes, such a little worm

  • First Published December 8, 2005
LETTER

Uneven distribution of expressed sequence tag loci on maize pachytene chromosomes

  • First Published December 7, 2005
Methods

Survey of allelic expression using EST mining

  • First Published October 26, 2005
LETTER

Large-scale recombination rate patterns are conserved among human populations

  • First Published October 26, 2005
LETTER

Genomic regions exhibiting positive selection identified from dense genotype data

  • First Published October 26, 2005
LETTER

Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants

  • First Published October 26, 2005
LETTER

Ascertainment bias in studies of human genome-wide polymorphism

  • First Published October 26, 2005
ARTICLE

SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27" > Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27

  • First Published October 26, 2005
Methods

Genomic scans for selective sweeps using SNP data

  • First Published October 26, 2005
LETTER

Segmental duplications and gene conversion: Human luteinizing hormone/chorionic gonadotropin β gene cluster

  • First Published October 26, 2005
LETTER

Genome-wide definitive haplotypes determined using a collection of complete hydatidiform moles

  • First Published October 26, 2005
PERSPECTIVE

Determinants of the success of whole-genome association testing

  • First Published October 26, 2005
RESOURCE

The International HapMap Project Web site

  • First Published October 26, 2005
RESOURCE

Inference and analysis of haplotypes from combined genotyping studies deposited in dbSNP

  • First Published October 26, 2005
LETTER

Sequence features in regions of weak and strong linkage disequilibrium

  • First Published October 26, 2005
Methods

Calibrating a coalescent simulation of human genome sequence variation

  • First Published October 26, 2005
ARTICLE

Measures of human population structure show heterogeneity among genomic regions

  • First Published October 26, 2005
ARTICLE

Traffic of genetic information between segmental duplications flanking the typical 22q11.2 deletion in velo-cardio-facial syndrome/DiGeorge syndrome

  • First Published October 26, 2005
LETTER

Evolutionary constraints in conserved nongenic sequences of mammals

  • First Published October 3, 2005
LETTER

Saccharomyces cerevisiae" > Identification of programmed translational -1 frameshifting sites in the genome of Saccharomyces cerevisiae

  • First Published October 3, 2005
LETTER

Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels

  • First Published October 3, 2005
Methods

Gene enrichment in maize with hypomethylated partial restriction (HMPR) libraries

  • First Published October 3, 2005
LETTER

Differential methylation of genes and repeats in land plants

  • First Published October 3, 2005
LETTER

Saccharomyces cerevisiae" > Metabolic functions of duplicate genes in Saccharomyces cerevisiae

  • First Published October 3, 2005
LETTER

C. elegans" > The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans

  • First Published October 3, 2005
LETTER

Mycobacterium tuberculosis Beijing genotype: Clues from human phylogeography" > Origin and primary dispersal of the Mycobacterium tuberculosis Beijing genotype: Clues from human phylogeography

  • First Published September 16, 2005
ARTICLE

Natronomonas pharaonis" > Living with two extremes: Conclusions from the genome sequence of Natronomonas pharaonis

  • First Published September 16, 2005
ARTICLE

De novo discovery of a tissue-specific gene regulatory module in a chordate

  • First Published September 16, 2005
RESOURCE

Galaxy: A platform for interactive large-scale genome analysis

  • First Published September 16, 2005
ARTICLE

Pseudoalteromonas haloplanktis TAC125" > Coping with cold: The genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125

  • First Published September 16, 2005
Methods

Simple, robust methods for high-throughput nanoliter-scale DNA sequencing

  • First Published September 16, 2005
LETTER

A genome-wide survey of structural variation between human and chimpanzee

  • First Published September 16, 2005
LETTER

The evolutionary fate of MULE-mediated duplications of host gene fragments in rice

  • First Published September 1, 2005
LETTER

Arabidopsis" > A microarray analysis of the rice transcriptome and its comparison to Arabidopsis

  • First Published September 1, 2005
LETTER

Fitting background-selection predictions to levels of nucleotide variation and divergence along the human autosomes

  • First Published September 1, 2005
LETTER

Ancient haplotypes of the HLA Class II region

  • First Published September 1, 2005
LETTER

Independent intrachromosomal recombination events underlie the pericentric inversions of chimpanzee and gorilla chromosomes homologous to human chromosome 16

  • First Published September 1, 2005
LETTER

Why do human diversity levels vary at a megabase scale?

  • First Published September 1, 2005
LETTER

Genomic deletions and precise removal of transposable elements mediated by short identical DNA segments in primates

  • First Published September 1, 2005
ARTICLE

Evolutionary mechanisms shaping the genomic structure of the Williams-Beuren syndrome chromosomal region at human 7q11.23

  • First Published September 1, 2005
ARTICLE

ATG deserts define a novel core promoter subclass

  • First Published August 18, 2005
ARTICLE

Gossypium and Arabidopsis: Unraveling the consequences of both ancient and recent polyploidy" > Comparative genomics of Gossypium and Arabidopsis: Unraveling the consequences of both ancient and recent polyploidy

  • First Published August 18, 2005
LETTER

Origin and evolution of new exons in rodents

  • First Published August 18, 2005
RESOURCE

The zebrafish gene map defines ancestral vertebrate chromosomes

  • First Published August 18, 2005
LETTER

An extraordinary retrotransposon family encoding dual endonucleases

  • First Published August 2, 2005
Methods

Ciona savignyi" > Assembly of polymorphic genomes: Algorithms and application to Ciona savignyi

  • First Published August 2, 2005
Methods

Region-specific detection of neuroblastoma loss of heterozygosity at multiple loci simultaneously using a SNP-based tag-array platform

  • First Published August 2, 2005
Methods

Estimating the tempo and mode of gene family evolution from comparative genomic data

  • First Published August 2, 2005
Methods

Recovering the geographic origin of early modern humans by realistic and spatially explicit simulations

  • First Published August 2, 2005
Methods

Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics

  • First Published August 2, 2005
LETTER

Gene-breaking: A new paradigm for human retrotransposon-mediated gene evolution

  • First Published July 15, 2005
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
LETTER

Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations

  • First Published July 15, 2005
Methods

Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis

  • First Published July 15, 2005
LETTER

The scale of mutational variation in the murid genome

  • First Published July 15, 2005
LETTER

Human ribosomal RNA gene arrays display a broad range of palindromic structures

  • First Published July 15, 2005
LETTER

Iroquois cluster gene deserts" > A functional survey of the enhancer activity of conserved non-coding sequences from vertebrate Iroquois cluster gene deserts

  • First Published July 15, 2005
RESOURCE

The MicrobesOnline Web site for comparative genomics

  • First Published July 5, 2005
Methods

Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays

  • First Published July 5, 2005
RESOURCE

An atlas of human gene expression from massively parallel signature sequencing (MPSS)

  • First Published July 5, 2005
Methods

Orthologous repeats and mammalian phylogenetic inference

  • First Published July 5, 2005
LETTER

Assessing the limits of genomic data integration for predicting protein networks

  • First Published July 5, 2005
LETTER

ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle" > Identification of a missense mutation in the bovine ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle

  • First Published July 5, 2005
Methods

BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population" > Mutation scanning by meltMADGE: Validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population

  • First Published July 5, 2005
LETTER

Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease

  • First Published June 17, 2005
ARTICLE

Distribution and intensity of constraint in mammalian genomic sequence

  • First Published June 17, 2005
LETTER

The net of life: Reconstructing the microbial phylogenetic network

  • First Published June 17, 2005
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