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Methods

cis-regulatory variation in human haplotypes" > Targeted screening of cis-regulatory variation in human haplotypes

  • First Published October 29, 2008
RESOURCE

A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: The NIH heterogeneous stock

  • First Published October 29, 2008
RESOURCE

Whole population, genome-wide mapping of hidden relatedness

  • First Published October 29, 2008
Insight/Outlook

Ethical, legal, and social considerations in conducting the Human Microbiome Project

  • First Published October 29, 2008
Methods

DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression

  • First Published October 29, 2008
Methods

Ortho-proteogenomics: Multiple proteomes investigation through orthology and a new MS-based protocol

  • First Published October 27, 2008
Methods

Most mammalian mRNAs are conserved targets of microRNAs

  • First Published October 27, 2008
LETTER

Comparative sequence analysis of primate subtelomeres originating from a chromosome fission event

  • First Published October 24, 2008
LETTER

Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex

  • First Published October 10, 2008
Methods

Nested Patch PCR enables highly multiplexed mutation discovery in candidate genes

  • First Published October 10, 2008
Methods

Enredo and Pecan: Genome-wide mammalian consistency-based multiple alignment with paralogs

  • First Published October 10, 2008
LETTER

In-depth characterization of the microRNA transcriptome in a leukemia progression model

  • First Published October 10, 2008
Methods

Genome-wide nucleotide-level mammalian ancestor reconstruction

  • First Published October 10, 2008
LETTER

Analysis of copy number variants and segmental duplications in the human genome: Evidence for a change in the process of formation in recent evolutionary history

  • First Published October 8, 2008
RESOURCE

genBlastA: Enabling BLAST to identify homologous gene sequences

  • First Published October 6, 2008
LETTER

Alu retrotransposons in the human genome" > Active Alu retrotransposons in the human genome

  • First Published October 3, 2008
RESOURCE

Haplotype sorting using human fosmid clone end-sequence pairs

  • First Published October 3, 2008
LETTER

Arabidopsis transposed after the origin of the order Brassicales" > Many or most genes in Arabidopsis transposed after the origin of the order Brassicales

  • First Published October 3, 2008
LETTER

E. coli" > Principles of transcriptional regulation and evolution of the metabolic system in E. coli

  • First Published October 3, 2008
LETTER

E2F in vivo binding specificity: Comparison of consensus versus nonconsensus binding sites

  • First Published October 3, 2008
Methods

Unraveling ancient hexaploidy through multiply-aligned angiosperm gene maps

  • First Published October 2, 2008
LETTER

Dispensability of mammalian DNA

  • First Published October 2, 2008
ERRATUM

Errata

  • First Published October 1, 2008
LETTER

Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif

  • First Published September 25, 2008
RESOURCE

Arabidopsis thaliana with short reads" > Sequencing of natural strains of Arabidopsis thaliana with short reads

  • First Published September 25, 2008
Methods

cis-regulatory elements" > Ab initio identification of functionally interacting pairs of cis-regulatory elements

  • First Published September 17, 2008
RESOURCE

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

  • First Published September 17, 2008
Methods

Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification

  • First Published September 16, 2008
LETTER

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

  • First Published September 11, 2008
Methods

Rapid whole-genome mutational profiling using next-generation sequencing technologies

  • First Published September 4, 2008
ARTICLE

Copy number variation and evolution in humans and chimpanzees

  • First Published September 4, 2008
LETTER

Unexpected complexity at breakpoint junctions in phenotypically normal individuals and mechanisms involved in generating balanced translocations t(1;22)(p36;q13)

  • First Published September 2, 2008
Methods

MEDME: An experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment

  • First Published September 2, 2008
Methods

Gene prediction in novel fungal genomes using an ab initio algorithm with unsupervised training

  • First Published August 29, 2008
ERRATUM

Erratum

  • First Published August 28, 2008
LETTER

HOX gene clusters" > Nucleosome positioning in human HOX gene clusters

  • First Published August 22, 2008
LETTER

Pathogen corruption and site-directed recombination at a plant disease resistance gene cluster

  • First Published August 21, 2008
LETTER

Copy number variation at the breakpoint region of isochromosome 17q

  • First Published August 19, 2008
RESOURCE

Mapping short DNA sequencing reads and calling variants using mapping quality scores

  • First Published August 19, 2008
LETTER

Escherichia coli" > Transcription of foreign DNA in Escherichia coli

  • First Published August 13, 2008
LETTER

Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity" > A novel mode of enhancer evolution: The Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity

  • First Published August 7, 2008
LETTER

A diverse set of microRNAs and microRNA-like small RNAs in developing rice grains

  • First Published August 7, 2008
LETTER

Impacts of protein–protein interaction domains on organism and network complexity

  • First Published August 7, 2008
LETTER

NPHP4) is associated with recessive cone-rod dystrophy in standard wire-haired dachshund" > A deletion in nephronophthisis 4 (NPHP4) is associated with recessive cone-rod dystrophy in standard wire-haired dachshund

  • First Published August 7, 2008
LETTER

Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties

  • First Published August 7, 2008
LETTER

Reduced purifying selection prevails over positive selection in human copy number variant evolution

  • First Published August 7, 2008
LETTER

Evolution of the mammalian transcription factor binding repertoire via transposable elements

  • First Published August 5, 2008
Methods

An MCMC algorithm for haplotype assembly from whole-genome sequence data

  • First Published August 1, 2008
ERRATUM

Errata

  • First Published August 1, 2008
PERSPECTIVE

The opossum genome: Insights and opportunities from an alternative mammal

  • First Published August 1, 2008
PERSPECTIVE

Genomic medicine in Mexico: Initial steps and the road ahead

  • First Published August 1, 2008
LETTER

Global organization of replication time zones of the mouse genome

  • First Published July 30, 2008
LETTER

Relaxation of yeast mitochondrial functions after whole-genome duplication

  • First Published July 30, 2008
PERSPECTIVE

Genome-wide analyses of alternative splicing in plants: Opportunities and challenges

  • First Published July 30, 2008
Methods

C. elegans gene annotations" > Use of shotgun proteomics for the identification, confirmation, and correction of C. elegans gene annotations

  • First Published July 24, 2008
LETTER

Deep sequencing of tomato short RNAs identifies microRNAs targeting genes involved in fruit ripening

  • First Published July 24, 2008
LETTER

Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement

  • First Published July 14, 2008
Methods

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

  • First Published July 10, 2008
LETTER

Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5′-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes

  • First Published July 9, 2008
LETTER

Very small mobile repeated elements in cyanobacterial genomes

  • First Published July 3, 2008
LETTER

DNA methylation and heterochromatinization in the male-specific region of the primitive Y chromosome of papaya

  • First Published July 1, 2008
LETTER

Drosophila melanogaster" > Accelerated sequence divergence of conserved genomic elements in Drosophila melanogaster

  • First Published June 26, 2008
LETTER

Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways" > Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways

  • First Published June 26, 2008
RESOURCE

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

  • First Published June 24, 2008
LETTER

Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation

  • First Published June 18, 2008
LETTER

Pervasive positive selection on duplicated and nonduplicated vertebrate protein coding genes

  • First Published June 18, 2008
Methods

Inferring causal relationships among different histone modifications and gene expression

  • First Published June 18, 2008
LETTER

The amphioxus genome illuminates vertebrate origins and cephalochordate biology

  • First Published June 18, 2008
LETTER

Insights from the amphioxus genome on the origin of vertebrate neural crest

  • First Published June 18, 2008
LETTER

Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity

  • First Published June 18, 2008
RESOURCE

Hylobates and Nomascus Gibbons by high-resolution synteny mapping" > Tracking the complex flow of chromosome rearrangements from the Hominoidea Ancestor to extant Hylobates and Nomascus Gibbons by high-resolution synteny mapping

  • First Published June 13, 2008
LETTER

A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome

  • First Published June 12, 2008
RESOURCE

EagleView: A genome assembly viewer for next-generation sequencing technologies

  • First Published June 11, 2008
LETTER

CpG dinucleotides and the mutation rate of non-CpG DNA

  • First Published June 11, 2008
LETTER

Drosophila" > On the origin of new genes in Drosophila

  • First Published June 11, 2008
Methods

RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays

  • First Published June 11, 2008
Next-Generation DNA Sequencing/Review

The new paradigm of flow cell sequencing

  • First Published June 2, 2008
RESOURCE

DupMasker: A tool for annotating primate segmental duplications" > DupMasker: A tool for annotating primate segmental duplications

  • First Published May 23, 2008
LETTER

Saccharomyces cerevisiae predicted ORFeome" > Revisiting the Saccharomyces cerevisiae predicted ORFeome

  • First Published May 23, 2008
LETTER

A diversity profile of the human skin microbiota

  • First Published May 23, 2008
Methods

A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations

  • First Published May 23, 2008
RESOURCE

A novel DNA sequence database for analyzing human demographic history

  • First Published May 20, 2008
LETTER

Cupriavidus taiwanensis and comparative genomics of rhizobia" > Genome sequence of the β-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia

  • First Published May 19, 2008
LETTER

A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3′ end RNA polyadenylation

  • First Published May 16, 2008
LETTER

TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing" > Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing

  • First Published May 14, 2008
LETTER

C. elegans reveals a lack of universal sequence-dictated positioning" > A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning

  • First Published May 13, 2008
RESOURCE

A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach

  • First Published May 9, 2008
LETTER

The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast

  • First Published May 7, 2008
Platypus Special/Letter

Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes

  • First Published May 7, 2008
LETTER

Transcription induces strand-specific mutations at the 5′ end of human genes

  • First Published May 7, 2008
Platypus Special/Letter

Retroposed SNOfall—A mammalian-wide comparison of platypus snoRNAs

  • First Published May 7, 2008
Platypus Special/Letter

Defensins and the convergent evolution of platypus and reptile venom genes

  • First Published May 7, 2008
Platypus Special/Letter

Origin of INSL3-mediated testicular descent in therian mammals

  • First Published May 7, 2008
Platypus Special/Letter

Conservation of small RNA pathways in platypus

  • First Published May 7, 2008
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