Your search for returned 6,372 results
Research
High-throughput allele-specific expression across 250 environmental conditions
- First Published October 19, 2016
Method
An integrated metagenomics pipeline for strain profiling reveals novel patterns of bacterial transmission and biogeography
- First Published October 18, 2016
Research
Macaca mulatta) based on whole-genome sequences" > The population genomics of rhesus macaques (Macaca mulatta) based on whole-genome sequences
- First Published October 17, 2016
Method
Centrifuge: rapid and sensitive classification of metagenomic sequences
- First Published October 17, 2016
Resource
Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver
- First Published October 13, 2016
Resource
Genome-wide dynamics of alternative polyadenylation in rice
- First Published October 12, 2016
Method
k-mer validation" > Improved assembly of noisy long reads by k-mer validation
- First Published October 7, 2016
Research
Interchromosomal core duplicons drive both evolutionary instability and disease susceptibility of the Chromosome 8p23.1 region
- First Published October 7, 2016
Corrigendum
Corrigendum: A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?
- First Published October 3, 2016
Research
Legionella pneumophila have emerged recently and independently" > Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently
- First Published September 23, 2016
Research
Nucleosomal signatures impose nucleosome positioning in coding and noncoding sequences in the genome
- First Published September 23, 2016
Research
Reconstructed cell fate–regulatory programs in stem cells reveal hierarchies and key factors of neurogenesis
- First Published September 20, 2016
Resource
Comprehensive variation discovery and recovery of missing sequence in the pig genome using multiple de novo assemblies
- First Published September 19, 2016
Method
Direct chromosome-length haplotyping by single-cell sequencing
- First Published September 19, 2016
Research
Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population
- First Published September 19, 2016
Research
NGS-based reverse genetic screen for common embryonic lethal mutations compromising fertility in livestock
- First Published September 19, 2016
Research
Saccharomyces cerevisiae" > RNA–DNA sequence differences in Saccharomyces cerevisiae
- First Published September 16, 2016
Research
Binding of nuclear factor κB to noncanonical consensus sites reveals its multimodal role during the early inflammatory response
- First Published September 15, 2016
Research
Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia
- First Published September 12, 2016
Research
Brachypodium distachyon align with underlying genetic diversity" > DNA methylation profiles of diverse Brachypodium distachyon align with underlying genetic diversity
- First Published September 9, 2016
Perspective
Dictyostelium discoideum" > A better way to discover gene function in the social amoeba Dictyostelium discoideum
- First Published September 1, 2016
Method
A generic, cost-effective, and scalable cell lineage analysis platform
- First Published August 24, 2016
Research
Common genomic elements promote transcriptional and DNA replication roadblocks
- First Published August 18, 2016
Resource
C. elegans" > The time-resolved transcriptome of C. elegans
- First Published August 16, 2016
Resource
Plasmodium falciparum" > Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum
- First Published August 16, 2016
Method
Inhibition of microRNA 128 promotes excitability of cultured cortical neuronal networks
- First Published August 11, 2016
Research
Drosophila spermatogenesis" > Critical roles of long noncoding RNAs in Drosophila spermatogenesis
- First Published August 11, 2016
Research
Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles
- First Published August 10, 2016
Research
Pangolin genomes and the evolution of mammalian scales and immunity
- First Published August 10, 2016
Research
Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation
- First Published August 2, 2016
Method
Characterizing polymorphic inversions in human genomes by single-cell sequencing
- First Published July 29, 2016
Research
Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin
- First Published July 28, 2016
Method
End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data
- First Published July 28, 2016
Method
A synergistic DNA logic predicts genome-wide chromatin accessibility
- First Published July 25, 2016
Research
Global deceleration of gene evolution following recent genome hybridizations in fungi
- First Published July 20, 2016
Research
The nonessentiality of essential genes in yeast provides therapeutic insights into a human disease
- First Published July 20, 2016
Research
SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells
- First Published July 19, 2016
Method
In silico phylogenomics using complete genomes: a case study on the evolution of hominoids
- First Published July 19, 2016
Research
Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young
- First Published July 19, 2016
Insight/Outlook
The ethics of conducting molecular autopsies in cases of sudden death in the young
- First Published July 13, 2016
Research
Novel features of telomere biology revealed by the absence of telomeric DNA methylation
- First Published July 12, 2016
Method
Integrative analysis with ChIP-seq advances the limits of transcript quantification from RNA-seq
- First Published July 12, 2016
Research
CENPT bridges adjacent CENPA nucleosomes on young human α-satellite dimers
- First Published July 6, 2016
Corrigendum
Corrigendum: Divergence of a conserved elongation factor and transcription regulation in budding and fission yeast
- First Published July 1, 2016
Resource
Diverse alternative back-splicing and alternative splicing landscape of circular RNAs
- First Published June 30, 2016
Research
Transposons passively and actively contribute to evolution of the two-speed genome of a fungal pathogen
- First Published June 20, 2016
Method
Heterogeneity of transcription factor binding specificity models within and across cell lines
- First Published June 16, 2016
Research
High-throughput functional comparison of promoter and enhancer activities
- First Published June 16, 2016
Method
Dictyostelium" > Gene discovery by chemical mutagenesis and whole-genome sequencing in Dictyostelium
- First Published June 15, 2016
Method
Multikernel linear mixed models for complex phenotype prediction
- First Published June 14, 2016
Research
Neurospora chromosomes are organized by blocks of importin alpha-dependent heterochromatin that are largely independent of H3K9me3" > Neurospora chromosomes are organized by blocks of importin alpha-dependent heterochromatin that are largely independent of H3K9me3
- First Published June 3, 2016
Method
TransRate: reference-free quality assessment of de novo transcriptome assemblies
- First Published June 1, 2016
Research
Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus
- First Published May 31, 2016
Research
Arabidopsis thaliana at single-gene resolution" > Genome-wide analysis of chromatin packing in Arabidopsis thaliana at single-gene resolution
- First Published May 25, 2016
Research
Elevated variant density around SV breakpoints in germline lineage lends support to error-prone replication hypothesis
- First Published May 23, 2016
Research
Global analysis of transcriptionally engaged yeast RNA polymerase III reveals extended tRNA transcripts
- First Published May 20, 2016
Research
Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants
- First Published May 18, 2016
Research
Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgression
- First Published May 18, 2016
Research
Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic
- First Published May 18, 2016
Research
Divergence of a conserved elongation factor and transcription regulation in budding and fission yeast
- First Published May 12, 2016
Research
A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer
- First Published May 10, 2016
Method
Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants
- First Published May 10, 2016
Research
The interaction of PRC2 with RNA or chromatin is mutually antagonistic
- First Published May 9, 2016
Research
A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes
- First Published May 6, 2016
Research
Venus flytrap carnivorous lifestyle builds on herbivore defense strategies
- First Published May 4, 2016
Method
Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks
- First Published May 3, 2016
Research
Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells
- First Published May 2, 2016
Resource
Improved definition of the mouse transcriptome via targeted RNA sequencing
- First Published May 2, 2016
Corrigendum
Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
- First Published May 2, 2016
Corrigendum
Corrigendum: Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies
- First Published May 2, 2016
Resource
Identification of the long, edited dsRNAome of LPS-stimulated immune cells
- First Published April 21, 2016
Research
cis-regulation in embryonic stem cells" > Interactions between pluripotency factors specify cis-regulation in embryonic stem cells
- First Published April 15, 2016
Method
A flexible method for estimating the fraction of fitness influencing mutations from large sequencing data sets
- First Published April 14, 2016
Method
SMASH, a fragmentation and sequencing method for genomic copy number analysis
- First Published April 14, 2016
Research
Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks
- First Published April 13, 2016
Research
Drosophila" > Evidence for the fixation of gene duplications by positive selection in Drosophila
- First Published April 12, 2016
Research
Zygotes segregate entire parental genomes in distinct blastomere lineages causing cleavage-stage chimerism and mixoploidy
- First Published April 12, 2016
Research
Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity
- First Published April 7, 2016
Research
Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations
- First Published April 6, 2016
Research
Sperm is epigenetically programmed to regulate gene transcription in embryos
- First Published March 31, 2016
Method
Sequence-targeted nucleosome sliding in vivo by a hybrid Chd1 chromatin remodeler
- First Published March 18, 2016
Research
nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
- First Published March 16, 2016
Method
An extended set of yeast-based functional assays accurately identifies human disease mutations
- First Published March 14, 2016
Research
Chlamydomonas reinhardtii are produced by Dicer-like 3-mediated cleavage of introns and untranslated regions of coding RNAs" > Most microRNAs in the single-cell alga Chlamydomonas reinhardtii are produced by Dicer-like 3-mediated cleavage of introns and untranslated regions of coding RNAs
- First Published March 11, 2016
Research
Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters
- First Published March 8, 2016
Research
4 grass" > Drought responsive gene expression regulatory divergence between upland and lowland ecotypes of a perennial C4 grass
- First Published March 7, 2016