Your search for returned 6,372 results
Research
Genome wide analysis of 3′ UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish
- First Published June 21, 2019
Research
Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer
- First Published June 20, 2019
Research
Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork
- First Published June 19, 2019
Research
Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin
- First Published June 14, 2019
Method
Single-molecule long-read sequencing reveals the chromatin basis of gene expression
- First Published June 14, 2019
Method
A novel synthetic-genetic-array–based yeast one-hybrid system for high discovery rate and short processing time
- First Published June 11, 2019
Resource
Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome
- First Published June 11, 2019
Research
Histone methyltransferase PRDM9 is not essential for meiosis in male mice
- First Published June 11, 2019
Method
A machine-learning approach for accurate detection of copy number variants from exome sequencing
- First Published June 6, 2019
Method
BiosyntheticSPAdes: reconstructing biosynthetic gene clusters from assembly graphs
- First Published June 3, 2019
Research
Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging
- First Published June 3, 2019
Method
methyl-ATAC-seq measures DNA methylation at accessible chromatin
- First Published June 3, 2019
Research
A massively parallel 3′ UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization
- First Published May 31, 2019
Research
Systems analysis reveals complex biological processes during virus infection fate decisions
- First Published May 28, 2019
Research
Diversification and collapse of a telomere elongation mechanism
- First Published May 28, 2019
Method
Crunch: integrated processing and modeling of ChIP-seq data in terms of regulatory motifs
- First Published May 28, 2019
Resource
Caenorhabditis elegans genome" > Recompleting the Caenorhabditis elegans genome
- First Published May 23, 2019
Resource
C. elegans" > Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans
- First Published May 23, 2019
Method
One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry
- First Published May 23, 2019
Research
4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in facioscapulohumeral muscular dystrophy
- First Published May 16, 2019
Method
Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes
- First Published May 16, 2019
Resource
Saccharomyces cerevisiae" > Pervasive and dynamic transcription initiation in Saccharomyces cerevisiae
- First Published May 10, 2019
Research
Human contamination in bacterial genomes has created thousands of spurious proteins
- First Published May 7, 2019
Method
Plasmid detection and assembly in genomic and metagenomic data sets
- First Published May 2, 2019
Research
Convergent recombination cessation between mating-type genes and centromeres in selfing anther-smut fungi
- First Published May 1, 2019
Erratum
Drosophila genus" > Erratum: Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus
- First Published May 1, 2019
Method
Beta-binomial modeling of CRISPR pooled screen data identifies target genes with greater sensitivity and fewer false negatives
- First Published April 23, 2019
Method
Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid
- First Published April 16, 2019
Research
Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its precancerous precursor state
- First Published April 8, 2019
Research
Interplay between coding and exonic splicing regulatory sequences
- First Published April 8, 2019
Research
DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries
- First Published April 4, 2019
Method
A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS
- First Published April 2, 2019
Resource
The accessible chromatin landscape of the murine hippocampus at single-cell resolution
- First Published April 1, 2019
Corrigendum
Corrigendum: Initiation of mtDNA transcription is followed by pausing, and diverges across human cell types and during evolution
- First Published April 1, 2019
Corrigendum
Corrigendum: H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells
- First Published April 1, 2019
Resource
Analysis of 100 high-coverage genomes from a pedigreed captive baboon colony
- First Published March 29, 2019
Research
Brown rat demography reveals pre-commensal structure in eastern Asia before expansion into Southeast Asia
- First Published March 25, 2019
Research
Enterococcus faecium hospital-adapted lineages in municipal wastewater treatment plants indicates widespread distribution and release into the environment" > Detection of vancomycin-resistant Enterococcus faecium hospital-adapted lineages in municipal wastewater treatment plants indicates widespread distribution and release into the environment
- First Published March 21, 2019
Research
The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes
- First Published March 21, 2019
Method
Resolving the full spectrum of human genome variation using Linked-Reads
- First Published March 20, 2019
Method
Identification of human silencers by correlating cross-tissue epigenetic profiles and gene expression
- First Published March 18, 2019
Research
Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin
- First Published March 14, 2019
Method
A virome-wide clonal integration analysis platform for discovering cancer viral etiology
- First Published March 14, 2019
Resource
GenTree, an integrated resource for analyzing the evolution and function of primate-specific coding genes
- First Published March 12, 2019
Resource
Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses
- First Published March 11, 2019
Research
Coexpression patterns define epigenetic regulators associated with neurological dysfunction
- First Published March 11, 2019
Method
Accurate analysis of genuine CRISPR editing events with ampliCan
- First Published March 8, 2019
Research
Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans
- First Published March 7, 2019
Corrigendum
Corrigendum: Inherited DNA methylation primes the establishment of accessible chromatin during genome activation
- First Published March 1, 2019
Method
Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin
- First Published February 26, 2019
Research
TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells
- First Published February 22, 2019
Research
Drosophila" > Cohesin occupancy and composition at enhancers and promoters are linked to DNA replication origin proximity in Drosophila
- First Published February 22, 2019
Method
Bayesian-based noninvasive prenatal diagnosis of single-gene disorders
- First Published February 20, 2019
Research
New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulation
- First Published February 19, 2019
Method
Improved discovery of genetic interactions using CRISPRiSeq across multiple environments
- First Published February 19, 2019
Research
Ribosomal DNA harbors an evolutionarily conserved clock of biological aging
- First Published February 14, 2019
Research
Evolution of gene regulation in ruminants differs between evolutionary breakpoint regions and homologous synteny blocks
- First Published February 13, 2019
Resource
Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development
- First Published February 13, 2019
Resource
Comprehensive, integrated, and phased whole-genome analysis of the primary ENCODE cell line K562
- First Published February 8, 2019
Method
Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes
- First Published February 4, 2019
Research
CG dinucleotides enhance promoter activity independent of DNA methylation
- First Published February 1, 2019
Research
Drosophila genome" > Chromatin architecture reorganization during neuronal cell differentiation in Drosophila genome
- First Published February 1, 2019
Method
Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells
- First Published January 29, 2019
Research
High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity
- First Published January 25, 2019
Research
Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination
- First Published January 25, 2019
Research
Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion
- First Published January 25, 2019
Method
Fast and flexible bacterial genomic epidemiology with PopPUNK
- First Published January 24, 2019
Research
Pou5f3, SoxB1, and Nanog remodel chromatin on high nucleosome affinity regions at zygotic genome activation
- First Published January 23, 2019
Method
Guide Positioning Sequencing identifies aberrant DNA methylation patterns that alter cell identity and tumor-immune surveillance networks
- First Published January 22, 2019
Research
A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA
- First Published January 22, 2019
Resource
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis
- First Published January 18, 2019
Research
Transcription factor activity and nucleosome organization in mitosis
- First Published January 17, 2019
Research
CTCF sites display cell cycle–dependent dynamics in factor binding and nucleosome positioning
- First Published January 17, 2019
Research
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network
- First Published January 16, 2019
Research
Most chromatin interactions are not in linkage disequilibrium
- First Published January 7, 2019
Resource
PepQuery enables fast, accurate, and convenient proteomic validation of novel genomic alterations
- First Published January 4, 2019
Research
An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells
- First Published January 3, 2019
Corrigendum
Corrigendum: RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases
- First Published January 2, 2019
Research
Pathogenicity and selective constraint on variation near splice sites
- First Published December 26, 2018
Research
Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs
- First Published December 26, 2018
Method
Identification of regulatory elements from nascent transcription using dREG
- First Published December 20, 2018
Resource
Saccharomyces cerevisiae" > Global analysis of protein homomerization in Saccharomyces cerevisiae
- First Published December 19, 2018
Method
Anchor: trans-cell type prediction of transcription factor binding sites
- First Published December 19, 2018
Research
Human papillomavirus and the landscape of secondary genetic alterations in oral cancers
- First Published December 18, 2018