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Method

High-resolution genotype-free mapping of genetic variation with CRI-SPA-Map

  • Sheila Lutz
  • Megan Lawler
  • Samuel Amidon
  • Frank W. Albert
  • First Published March 23, 2026
Method

Restoring the potency of a neutralizing antibody via guided hypermutation with hyper-antibody editor HAE1

  • Yuhong Wang
  • Yuefeng Guo
  • Qiuyu Lu
  • Xinyi Liu
  • Haoqi Xu
  • Jiayi Chen Ruiqi Pi Shaopeng Yuan Ziting Yang
  • ... [+4 authors] ...,
  • Rusen Lu
  • Fei-Long Meng
  • Tingting Gan
  • Jiazhi Hu
  • First Published March 19, 2026
Method

Parallel analysis of replication timing, gene expression, and copy number with PARTAGE

  • Lakshana Sruthi Sadu Murari
  • Quinn Dickinson
  • Silvia Meyer-Nava
  • Juan Carlos Rivera-Mulia
  • First Published March 19, 2026
Research

cis-antisense RNA duplexes" > A transcriptome-wide systematic search does not detect A-to-I RNA editing in cis-antisense RNA duplexes

  • Zohar Rosenwasser
  • Roni Cohen-Fultheim
  • Ofir Shliefer
  • Erez Y. Levanon
  • Eli Eisenberg
  • First Published March 12, 2026
Method

Scalable cell-specific coexpression networks for granular regulatory pattern discovery with NeighbourNet

  • Yidi Deng
  • Jiadong Mao
  • Jarny Choi
  • Kim-Anh Lê Cao
  • First Published March 5, 2026
Method

Minimizing reference bias with an imputed personalized reference

  • Kavya Vaddadi
  • Mao-Jan Lin
  • Sina Majidian
  • Taher Mun
  • Ben Langmead
  • First Published March 5, 2026
Method

Automated interpretable artificial intelligence genomic prediction with AIGP

  • Lei Wei
  • Ziqin Jiang
  • Baoliang Fan
  • Yidan Yan
  • Zhenqiang Xu
  • Xiaoxiang Hu
  • Yuzhe Wang
  • First Published March 5, 2026
Resource

Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease

  • Kangli Wang
  • Weikun Xia
  • Yingli Gu
  • Songpeng Zu
  • Qian Yang
  • Maria Luisa Amaral Yaozhi Wang
  • ... [+2 authors] ...,
  • Allen Wang
  • Xiang-Dong Fu
  • William C. Mobley
  • Bing Ren
  • First Published March 4, 2026
Research

Confounding factors in assessing the enriched expression of somatic mutant alleles in bulk tumor samples

  • Kohei Hagiwara
  • Andrew Thrasher
  • Nadezhda V. Terekhanova
  • Jinghui Zhang
  • First Published March 4, 2026
Research

cis-regulatory modules acting during vertebrate organogenesis" > Functional genomics analysis of developing zebrafish and human endoderm reveals highly conserved cis-regulatory modules acting during vertebrate organogenesis

  • Daniela M. Riley
  • Randa Elsayed
  • Mark D. Walsh
  • Simaran Johal
  • Ying Lin
  • Harry Walton
  • Till Bretschneider
  • Sascha Ott
  • Andrew C. Nelson
  • First Published March 4, 2026
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