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Resource

Allele-specific transcription factor binding across human brain regions offers mechanistic insight into eQTLs

  • First Published August 16, 2024
Method

cis-regulatory elements" > Probabilistic association of differentially expressed genes with cis-regulatory elements

  • First Published April 17, 2024
Research

Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells

  • First Published October 18, 2023
In memoriam

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022
In memoriam

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022
Research

Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

  • First Published April 20, 2021
Research

Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages" > Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages

  • First Published November 18, 2020
Research

Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations

  • First Published July 2, 2020
Resource

Dynamics of microRNA expression during mouse prenatal development

  • First Published October 23, 2019
Method

A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS

  • First Published April 2, 2019
Corrigendum

Corrigendum: Discovery and genotyping of structural variation from long-read haploid genome sequence data

  • First Published January 2, 2018
Resource

A genome-wide interactome of DNA-associated proteins in the human liver

  • First Published October 11, 2017
Corrigendum

Corrigendum: The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2

  • First Published September 1, 2017
Resource

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

  • First Published April 10, 2017
Research

Discovery and genotyping of structural variation from long-read haploid genome sequence data

  • First Published November 28, 2016
Research

Interchromosomal core duplicons drive both evolutionary instability and disease susceptibility of the Chromosome 8p23.1 region

  • First Published October 7, 2016
Research

Pangolin genomes and the evolution of mammalian scales and immunity

  • First Published August 10, 2016
Method

INTEGRATE: gene fusion discovery using whole genome and transcriptome data

  • First Published November 10, 2015
Research

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

  • First Published October 20, 2015
Resource

Chlorocebus aethiops sabaeus)" > The genome of the vervet (Chlorocebus aethiops sabaeus)

  • First Published September 16, 2015
Method

CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins

  • First Published September 9, 2015
Resource

Single haplotype assembly of the human genome from a hydatidiform mole

  • First Published November 4, 2014
Resource

Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline

  • First Published March 27, 2014
Method

Reconstructing complex regions of genomes using long-read sequencing technology

  • First Published January 13, 2014
Method

From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

  • First Published December 3, 2013
Resource

Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps

  • First Published October 29, 2013
Resource

Dynamic DNA methylation across diverse human cell lines and tissues

  • First Published January 16, 2013
Research

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

  • First Published September 26, 2012
Research

Widespread plasticity in CTCF occupancy linked to DNA methylation

  • First Published September 5, 2012
Resource

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

  • First Published September 5, 2012
Resource

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  • First Published September 5, 2012
Resource

MuSiC: Identifying mutational significance in cancer genomes

  • First Published July 3, 2012
Research

The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2

  • First Published March 14, 2012
Research

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

  • First Published February 2, 2012
Resource

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

  • First Published February 2, 2012
Method

Transposase mediated construction of RNA-seq libraries

  • First Published November 29, 2011
Research

Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee

  • First Published June 17, 2011
Research

DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer

  • First Published April 26, 2011
Research

Sequence features that drive human promoter function and tissue specificity

  • First Published May 25, 2010
Letter

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

  • First Published January 12, 2010
Article

Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation

  • First Published October 2, 2009
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
Letter

Signals of recent positive selection in a worldwide sample of human populations

  • First Published March 23, 2009
Methods

Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver

  • First Published March 9, 2009
LETTER

Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

  • First Published November 24, 2008
RESOURCE

Haplotype sorting using human fosmid clone end-sequence pairs

  • First Published October 3, 2008
LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

  • First Published February 7, 2008
ARTICLE

Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome

  • First Published June 13, 2007
ARTICLE

Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
LETTER

Transcription factor binding and modified histones in human bidirectional promoters

  • First Published June 13, 2007
RESOURCE

PolyScan: An automatic indel and SNP detection approach to the analysis of human resequencing data

  • First Published April 6, 2007
LETTER

Serum response factor binding sites differ in three human cell types

  • First Published January 2, 2007
RESOURCE

Molecular refinement of gibbon genome rearrangements

  • First Published December 21, 2006
LETTER

Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire

  • First Published September 8, 2006
Methods

Physical map-assisted whole-genome shotgun sequence assemblies

  • First Published June 1, 2006
RESOURCE

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

  • First Published May 3, 2006
ARTICLE

Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome

  • First Published December 12, 2005
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
LETTER

Punctuated duplication seeding events during the evolution of human chromosome 2p11

  • First Published June 17, 2005
Methods

Direct isolation and identification of promoters in the human genome

  • First Published May 17, 2005
RESOURCE

EAnnot: A genome annotation tool using experimental evidence

  • First Published December 1, 2004
ARTICLE

Coelacanth genome sequence reveals the evolutionary history of vertebrate genes

  • First Published November 15, 2004
LETTER

Analysis of Human mRNAs With the Reference Genome Sequence Reveals Potential Errors, Polymorphisms, and RNA Editing

  • First Published October 15, 2004
Chicken Special/Letters

The repetitive landscape of the chicken genome

  • First Published July 15, 2004
LETTER

Gene Conversion and the Evolution of Protocadherin Gene Cluster Diversity

  • First Published March 1, 2004
LETTER

An Abundance of Bidirectional Promoters in the Human Genome

  • First Published January 5, 2004
Methods

Identification of Promoter Regions in the Human Genome by Using a Retroviral Plasmid Library-Based Functional Reporter Gene Assay

  • First Published June 12, 2003
METHODS

Identification and Functional Analysis of Human Transcriptional Promoters

  • First Published February 1, 2003
METHODS

Rapid Mapping of Zebrafish Mutations With SNPs and Oligonucleotide Microarrays

  • First Published December 1, 2002
INSIGHT/OUTLOOK

What is Finished, and Why Does it Matter

  • First Published May 1, 2002
LETTER

Comparative DNA Sequence Analysis of Mouse and Human Protocadherin Gene Clusters

  • First Published March 1, 2001
METHODS

Theories and Applications for Sequencing Randomly Selected Clones

  • First Published January 18, 2001
LETTER

A Pneumatic Device for Rapid Loading of DNA Sequencing Gels

  • First Published May 1, 1998
LETTER

High Throughput Fingerprint Analysis of Large-Insert Clones

  • First Published November 1, 1997
RESEARCH

An STS-Based Radiation Hybrid Map of the Human Genome

  • First Published May 1, 1997
GENOME METHODS

A Transposon-Based Strategy for Sequencing Repetitive DNA in Eukaryotic Genomes

  • First Published May 1, 1997
EDITORIAL

The End of the Beginning: The Race to Begin Human Genome Sequencing

  • First Published September 1, 1996
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