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Resource

Allele-specific transcription factor binding across human brain regions offers mechanistic insight into eQTLs

  • First Published August 16, 2024
Method

cis-regulatory elements" > Probabilistic association of differentially expressed genes with cis-regulatory elements

  • First Published April 17, 2024
Research

Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells

  • First Published October 18, 2023
In memoriam

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022
In memoriam

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022
Research

Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

  • First Published April 20, 2021
Research

Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations

  • First Published July 2, 2020
Resource

Dynamics of microRNA expression during mouse prenatal development

  • First Published October 23, 2019
Method

A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS

  • First Published April 2, 2019
Resource

A genome-wide interactome of DNA-associated proteins in the human liver

  • First Published October 11, 2017
Research

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

  • First Published October 20, 2015
Method

CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins

  • First Published September 9, 2015
Method

From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

  • First Published December 3, 2013
Resource

Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps

  • First Published October 29, 2013
Research

DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast

  • First Published June 20, 2013
Resource

Dynamic DNA methylation across diverse human cell lines and tissues

  • First Published January 16, 2013
Research

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

  • First Published September 26, 2012
Resource

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

  • First Published September 5, 2012
Resource

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  • First Published September 5, 2012
Research

Widespread plasticity in CTCF occupancy linked to DNA methylation

  • First Published September 5, 2012
Research

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

  • First Published February 2, 2012
Method

Transposase mediated construction of RNA-seq libraries

  • First Published November 29, 2011
Research

DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer

  • First Published April 26, 2011
Research

Sequence features that drive human promoter function and tissue specificity

  • First Published May 25, 2010
Letter

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

  • First Published January 12, 2010
Article

Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation

  • First Published October 2, 2009
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
Letter

Signals of recent positive selection in a worldwide sample of human populations

  • First Published March 23, 2009
Methods

Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver

  • First Published March 9, 2009
LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

  • First Published February 7, 2008
ARTICLE

Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome

  • First Published June 13, 2007
ARTICLE

Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions

  • First Published June 13, 2007
LETTER

Transcription factor binding and modified histones in human bidirectional promoters

  • First Published June 13, 2007
LETTER

Serum response factor binding sites differ in three human cell types

  • First Published January 2, 2007
LETTER

Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire

  • First Published September 8, 2006
RESOURCE

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

  • First Published May 3, 2006
ARTICLE

Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome

  • First Published December 12, 2005
Methods

Direct isolation and identification of promoters in the human genome

  • First Published May 17, 2005
ARTICLE

Coelacanth genome sequence reveals the evolutionary history of vertebrate genes

  • First Published November 15, 2004
LETTER

Gene Conversion and the Evolution of Protocadherin Gene Cluster Diversity

  • First Published March 1, 2004
LETTER

An Abundance of Bidirectional Promoters in the Human Genome

  • First Published January 5, 2004
Methods

Identification of Promoter Regions in the Human Genome by Using a Retroviral Plasmid Library-Based Functional Reporter Gene Assay

  • First Published June 12, 2003
METHODS

Identification and Functional Analysis of Human Transcriptional Promoters

  • First Published February 1, 2003
METHODS

Rapid Mapping of Zebrafish Mutations With SNPs and Oligonucleotide Microarrays

  • First Published December 1, 2002
LETTER

Comparative DNA Sequence Analysis of Mouse and Human Protocadherin Gene Clusters

  • First Published March 1, 2001
RESEARCH

An STS-Based Radiation Hybrid Map of the Human Genome

  • First Published May 1, 1997
EDITORIAL

The End of the Beginning: The Race to Begin Human Genome Sequencing

  • First Published September 1, 1996
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