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Allele-specific transcription factor binding across human brain regions offers mechanistic insight into eQTLs

  • First Published August 16, 2024

cis-regulatory elements" > Probabilistic association of differentially expressed genes with cis-regulatory elements

  • First Published April 17, 2024

Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells

  • First Published October 18, 2023

Precision environmental health monitoring by longitudinal exposome and multi-omics profiling

  • First Published June 6, 2022

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022

Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

  • First Published April 20, 2021

Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations

  • First Published July 2, 2020

Dynamics of microRNA expression during mouse prenatal development

  • First Published October 23, 2019

A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS

  • First Published April 2, 2019

Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome

  • First Published December 1, 2017

A genome-wide interactome of DNA-associated proteins in the human liver

  • First Published October 11, 2017

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

  • First Published October 20, 2015

CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins

  • First Published September 9, 2015

From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

  • First Published December 3, 2013

Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps

  • First Published October 29, 2013

Dynamic DNA methylation across diverse human cell lines and tissues

  • First Published January 16, 2013

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

  • First Published September 26, 2012

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

  • First Published September 5, 2012

A highly integrated and complex PPARGC1A transcription factor binding network in HepG2 cells

  • First Published September 5, 2012

Widespread plasticity in CTCF occupancy linked to DNA methylation

  • First Published September 5, 2012

Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements

  • First Published September 5, 2012

Linking disease associations with regulatory information in the human genome

  • First Published September 5, 2012

Annotation of functional variation in personal genomes using RegulomeDB

  • First Published September 5, 2012

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

  • First Published September 5, 2012

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  • First Published September 5, 2012

Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

  • First Published September 5, 2012

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

  • First Published February 2, 2012

Transposase mediated construction of RNA-seq libraries

  • First Published November 29, 2011

DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer

  • First Published April 26, 2011

CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

  • First Published February 7, 2011

C. elegans" > Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans

  • First Published December 22, 2010

C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data" > Prediction and characterization of noncoding RNAs in C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data

  • First Published December 22, 2010

Candida albicans using RNA-seq" > Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq

  • First Published September 1, 2010

Sequence features that drive human promoter function and tissue specificity

  • First Published May 25, 2010

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

  • First Published January 12, 2010

Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation

  • First Published October 2, 2009

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009

Signals of recent positive selection in a worldwide sample of human populations

  • First Published March 23, 2009

Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver

  • First Published March 9, 2009

MSB: A mean-shift-based approach for the analysis of structural variation in the genome

  • First Published November 26, 2008

Analysis of copy number variants and segmental duplications in the human genome: Evidence for a change in the process of formation in recent evolutionary history

  • First Published October 8, 2008

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

  • First Published September 11, 2008

A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3′ end RNA polyadenylation

  • First Published May 16, 2008

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

  • First Published February 7, 2008

Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome

  • First Published June 13, 2007

The DART classification of unannotated transcription within the ENCODE regions: Associating transcription with known and novel loci

  • First Published June 13, 2007

Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions

  • First Published June 13, 2007

Statistical analysis of the genomic distribution and correlation of regulatory elements in the ENCODE regions

  • First Published June 13, 2007

Transcription factor binding and modified histones in human bidirectional promoters

  • First Published June 13, 2007

Pseudogenes in the ENCODE regions: Consensus annotation, analysis of transcription, and evolution

  • First Published June 13, 2007

Structured RNAs in the ENCODE selected regions of the human genome

  • First Published June 13, 2007

Mapping of transcription factor binding regions in mammalian cells by ChIP: Comparison of array- and sequencing-based technologies

  • First Published June 13, 2007

Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE)

  • First Published June 13, 2007

What is a gene, post-ENCODE? History and updated definition

  • First Published June 13, 2007

Serum response factor binding sites differ in three human cell types

  • First Published January 2, 2007

Assessing the performance of different high-density tiling microarray strategies for mapping transcribed regions of the human genome

  • First Published November 21, 2006

Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire

  • First Published September 8, 2006

Predicting essential genes in fungal genomes

  • First Published August 9, 2006

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

  • First Published May 3, 2006

Design optimization methods for genomic DNA tiling arrays

  • First Published December 19, 2005

Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome

  • First Published December 12, 2005

Direct isolation and identification of promoters in the human genome

  • First Published May 17, 2005

Coelacanth genome sequence reveals the evolutionary history of vertebrate genes

  • First Published November 15, 2004

Large-Scale Mutagenesis of the Yeast Genome Using a Tn7-Derived Multipurpose Transposon

  • First Published October 1, 2004

Gene Conversion and the Evolution of Protocadherin Gene Cluster Diversity

  • First Published March 1, 2004

An Abundance of Bidirectional Promoters in the Human Genome

  • First Published January 5, 2004

Identification of Promoter Regions in the Human Genome by Using a Retroviral Plasmid Library-Based Functional Reporter Gene Assay

  • First Published June 12, 2003

Identification and Functional Analysis of Human Transcriptional Promoters

  • First Published February 1, 2003

Rapid Mapping of Zebrafish Mutations With SNPs and Oligonucleotide Microarrays

  • First Published December 1, 2002

Comparative DNA Sequence Analysis of Mouse and Human Protocadherin Gene Clusters

  • First Published March 1, 2001

An STS-Based Radiation Hybrid Map of the Human Genome

  • First Published May 1, 1997

The End of the Beginning: The Race to Begin Human Genome Sequencing

  • First Published September 1, 1996
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