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Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • First Published June 8, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • First Published March 14, 2016
Method

Read clouds uncover variation in complex regions of the human genome

  • First Published August 18, 2015
Method

Parente2: a fast and accurate method for detecting identity by descent

  • First Published October 1, 2014
Research

Genome evolution during progression to breast cancer

  • First Published April 8, 2013
Method

Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements

  • First Published September 5, 2012
Resource

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  • First Published September 5, 2012
Method

Linking disease associations with regulatory information in the human genome

  • First Published September 5, 2012
Letter

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

  • First Published January 12, 2010
Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

  • First Published October 2, 2009
Resource

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

  • First Published June 23, 2009
Methods

Shifted Transversal Design smart-pooling for high coverage interactome mapping

  • First Published May 15, 2009
LETTER

Saccharomyces cerevisiae predicted ORFeome" > Revisiting the Saccharomyces cerevisiae predicted ORFeome

  • First Published May 23, 2008
RECOMB Special/Methods

Effect of genetic divergence in identifying ancestral origin using HAPAA

  • First Published March 18, 2008
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
ARTICLE

Distribution and intensity of constraint in mammalian genomic sequence

  • First Published June 17, 2005
RESOURCE

C. elegans ORFeome by cloning TWINSCAN predictions" > Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions

  • First Published April 1, 2005
LETTER

C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones" > New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones

  • First Published February 1, 2005
RESOURCE

Caenorhabditis elegans Promoterome" > A First Version of the Caenorhabditis elegans Promoterome

  • First Published October 15, 2004
PERSPECTIVE

ORFeome Cloning and Systems Biology: Standardized Mass Production of the Parts From the Parts-List

  • First Published October 15, 2004
Insight/Outlook

Academia-Industry Collaboration: An Integral Element for Building “Omic” Resources

  • First Published October 15, 2004
RESOURCE

Human ORFeome Version 1.1: A Platform for Reverse Proteomics

  • First Published October 15, 2004
RESOURCE

Brucella melitensis ORFeome Version 1.1" > Generation of the Brucella melitensis ORFeome Version 1.1

  • First Published October 15, 2004
Methods

A Gateway-Compatible Yeast One-Hybrid System

  • First Published October 15, 2004
Methods

C. elegans Proteins" > High-Throughput Expression of C. elegans Proteins

  • First Published October 15, 2004
LETTER

C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions" > C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions

  • First Published October 15, 2004
Methods

Annotation Transfer Between Genomes: Protein–Protein Interologs and Protein–DNA Regulogs

  • First Published June 1, 2004
Methods

Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human

  • First Published April 1, 2004
LETTER

Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes

  • First Published April 1, 2004
Methods

Eukaryotic Regulatory Element Conservation Analysis and Identification Using Comparative Genomics

  • First Published March 1, 2004
Methods

Identification of Promoter Regions in the Human Genome by Using a Retroviral Plasmid Library-Based Functional Reporter Gene Assay

  • First Published June 12, 2003
LETTER

Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes

  • First Published May 1, 2003
METHODS

LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA

  • First Published March 12, 2003
METHODS

ARACHNE: A Whole-Genome Shotgun Assembler

  • First Published January 1, 2002
METHODS

Identification of Potential Interaction Networks Using Sequence-Based Searches for Conserved Protein-Protein Interactions or “Interologs”

  • First Published December 1, 2001
LETTER

Human and Mouse Gene Structure: Comparative Analysis and Application to Exon Prediction

  • First Published July 1, 2000
RESEARCH

Sequencing a Genome by Walking with Clone-End Sequences: A Mathematical Analysis

  • First Published December 1, 1999
METHODS

A Genetic Strategy to Eliminate Self-Activator Baits Prior to High-Throughput Yeast Two-Hybrid Screens

  • First Published November 1, 1999
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