Method
Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data
- First Published May 24, 2022
Research
Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals
- First Published June 21, 2021
Method
Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants
- First Published August 23, 2018
Research
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding
- First Published August 10, 2018
Research
Massive variation of short tandem repeats with functional consequences across strains of Arabidopsis thaliana
- First Published July 3, 2018
Method
Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis
- First Published October 11, 2017
Method
Co-expression networks reveal the tissue-specific regulation of transcription and splicing
- First Published October 11, 2017
Research
Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha
- First Published April 6, 2017
Method
A flexible method for estimating the fraction of fitness influencing mutations from large sequencing data sets
- First Published April 14, 2016
Research
Comprehensive identification and analysis of human accelerated regulatory DNA
- First Published June 23, 2015
Research
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
- First Published May 29, 2015
Research
Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast
- First Published May 29, 2013
Research
DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types
- First Published May 8, 2013
Research
A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity
- First Published April 1, 2013
Research
Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions
- First Published March 12, 2013
Research
Personal and population genomics of human regulatory variation
- First Published September 5, 2012
Research
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
- First Published February 2, 2012
Research
Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells
- First Published November 16, 2011
Method
A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data
- First Published August 26, 2011
Research
Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration
- First Published July 27, 2011
Resource
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
- First Published July 12, 2011
Method
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells
- First Published November 24, 2010
Research
Signatures of positive selection apparent in a small sample of human exomes
- First Published August 6, 2010
Perspective
Constructing genomic maps of positive selection in humans: Where do we go from here?
- First Published May 1, 2009
Letter
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns
- First Published February 27, 2009
Resource
The genomic architecture of segmental duplications and associated copy number variants in dogs
- First Published January 7, 2009
LETTER
Genomic signatures of positive selection in humans and the limits of outlier approaches
- First Published July 6, 2006
LETTER
Fitting background-selection predictions to levels of nucleotide variation and divergence along the human autosomes
- First Published September 1, 2005
Methods
Simultaneous genotyping, gene-expression measurement, and detection of allele-specific expression with oligonucleotide arrays
- First Published February 1, 2005
LETTER
Interrogating a High-Density SNP Map for Signatures of Natural Selection
- First Published December 1, 2002