Resource
Allele-specific transcription factor binding across human brain regions offers mechanistic insight into eQTLs
- First Published August 16, 2024
Method
cis-regulatory elements" > Probabilistic association of differentially expressed genes with cis-regulatory elements
- First Published April 17, 2024
Research
Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells
- First Published October 18, 2023
Research
Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands
- First Published April 20, 2021
Research
Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations
- First Published July 2, 2020
Resource
Dynamics of microRNA expression during mouse prenatal development
- First Published October 23, 2019
Method
A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS
- First Published April 2, 2019
Resource
A genome-wide interactome of DNA-associated proteins in the human liver
- First Published October 11, 2017
Research
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites
- First Published October 20, 2015
Method
CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins
- First Published September 9, 2015
Corrigendum
Corrigendum: Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells
- First Published September 1, 2015
Research
Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells
- First Published March 19, 2015
Research
RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts
- First Published December 18, 2014
Research
Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes
- First Published November 3, 2014
Research
Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia" > Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
- First Published September 15, 2014
Method
From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing
- First Published December 3, 2013
Resource
Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps
- First Published October 29, 2013
Resource
Dynamic DNA methylation across diverse human cell lines and tissues
- First Published January 16, 2013
Research
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner
- First Published September 26, 2012
Research
Widespread plasticity in CTCF occupancy linked to DNA methylation
- First Published September 5, 2012
Resource
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
- First Published September 5, 2012
Resource
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- First Published September 5, 2012
Research
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
- First Published February 2, 2012
Method
Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA
- First Published November 16, 2011
Research
DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer
- First Published April 26, 2011
Research
Natural genetic variation caused by small insertions and deletions in the human genome
- First Published April 1, 2011
Research
A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution
- First Published August 24, 2010
Research
Massive turnover of functional sequence in human and other mammalian genomes
- First Published August 6, 2010
Research
Sequence features that drive human promoter function and tissue specificity
- First Published May 25, 2010
Method
Genome assembly quality: Assessment and improvement using the neutral indel model
- First Published March 19, 2010
Letter
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
- First Published January 12, 2010
Article
Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation
- First Published October 2, 2009
Letter
Signals of recent positive selection in a worldwide sample of human populations
- First Published March 23, 2009
Methods
Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver
- First Published March 9, 2009
LETTER
Reduced purifying selection prevails over positive selection in human copy number variant evolution
- First Published August 7, 2008
Platypus Special/Letter
Defensins and the convergent evolution of platypus and reptile venom genes
- First Published May 7, 2008
LETTER
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets
- First Published February 7, 2008
12 Drosophila Genomes/Letter
Drosophila genomes" > Evolutionary rate analyses of orthologs and paralogs from 12 Drosophila genomes
- First Published November 7, 2007
ARTICLE
Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome
- First Published June 13, 2007
ARTICLE
Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions
- First Published June 13, 2007
LETTER
Transcription factor binding and modified histones in human bidirectional promoters
- First Published June 13, 2007
ARTICLE
Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs
- First Published March 26, 2007
LETTER
Serum response factor binding sites differ in three human cell types
- First Published January 2, 2007
LETTER
Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire
- First Published September 8, 2006
ARTICLE
Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome
- First Published December 12, 2005
Dog Special/Letters
Hotspots of mutation and breakage in dog and human chromosomes
- First Published December 8, 2005
Methods
Direct isolation and identification of promoters in the human genome
- First Published May 17, 2005
ARTICLE
Coelacanth genome sequence reveals the evolutionary history of vertebrate genes
- First Published November 15, 2004
LETTER
Comparative Evolutionary Genomics of Androgen-Binding Protein Genes
- First Published July 15, 2004
LETTER
Evolution and Comparative Genomics of Odorant- and Pheromone-Associated Genes in Rodents
- First Published April 1, 2004
LETTER
Occurrence and Consequences of Coding Sequence Insertions and Deletions in Mammalian Genomes
- First Published April 1, 2004
LETTER
Gene Conversion and the Evolution of Protocadherin Gene Cluster Diversity
- First Published March 1, 2004
LETTER
Elevated Rates of Protein Secretion, Evolution, and Disease Among Tissue-Specific Genes
- First Published January 5, 2004
Methods
Identification of Promoter Regions in the Human Genome by Using a Retroviral Plasmid Library-Based Functional Reporter Gene Assay
- First Published June 12, 2003
METHODS
Identification and Functional Analysis of Human Transcriptional Promoters
- First Published February 1, 2003
METHODS
Rapid Mapping of Zebrafish Mutations With SNPs and Oligonucleotide Microarrays
- First Published December 1, 2002
LETTER
Predicting Protein Cellular Localization Using a Domain Projection Method
- First Published August 1, 2002
LETTER
Systematic Identification of Novel Protein Domain Families Associated with Nuclear Functions
- First Published January 1, 2002
LETTER
Comparative DNA Sequence Analysis of Mouse and Human Protocadherin Gene Clusters
- First Published March 1, 2001
EDITORIAL
The End of the Beginning: The Race to Begin Human Genome Sequencing
- First Published September 1, 1996