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Research

CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain" > Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain

  • First Published September 25, 2024
Research

CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors" > Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors

  • First Published February 14, 2024
Research

Functional characterization of enhancer activity during a long terminal repeat's evolution

  • First Published October 3, 2022
Research

Genomic environments scale the activities of diverse core promoters

  • First Published December 27, 2021
Research

cis-regulatory activity" > Local sequence features that influence AP-1 cis-regulatory activity

  • First Published January 5, 2018
Research

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

  • First Published October 20, 2015
Method

Read clouds uncover variation in complex regions of the human genome

  • First Published August 18, 2015
Method

Parente2: a fast and accurate method for detecting identity by descent

  • First Published October 1, 2014
Research

High-throughput functional testing of ENCODE segmentation predictions

  • First Published July 17, 2014
Method

Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants

  • First Published August 6, 2013
Research

Genome evolution during progression to breast cancer

  • First Published April 8, 2013
Method

Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements

  • First Published September 5, 2012
Resource

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  • First Published September 5, 2012
Method

Linking disease associations with regulatory information in the human genome

  • First Published September 5, 2012
Research

TATA is a modular component of synthetic promoters

  • First Published July 13, 2010
Letter

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

  • First Published January 12, 2010
RECOMB Special/Methods

Effect of genetic divergence in identifying ancestral origin using HAPAA

  • First Published March 18, 2008
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
Methods

Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics

  • First Published August 2, 2005
ARTICLE

Distribution and intensity of constraint in mammalian genomic sequence

  • First Published June 17, 2005
Methods

Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human

  • First Published April 1, 2004
LETTER

Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes

  • First Published April 1, 2004
Methods

Eukaryotic Regulatory Element Conservation Analysis and Identification Using Comparative Genomics

  • First Published March 1, 2004
Methods

Identification of Promoter Regions in the Human Genome by Using a Retroviral Plasmid Library-Based Functional Reporter Gene Assay

  • First Published June 12, 2003
LETTER

Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes

  • First Published May 1, 2003
METHODS

LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA

  • First Published March 12, 2003
METHODS

ARACHNE: A Whole-Genome Shotgun Assembler

  • First Published January 1, 2002
LETTER

Human and Mouse Gene Structure: Comparative Analysis and Application to Exon Prediction

  • First Published July 1, 2000
RESEARCH

Sequencing a Genome by Walking with Clone-End Sequences: A Mathematical Analysis

  • First Published December 1, 1999
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