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Synergistic regulation by H3K36 and H3K27 methylation defines the chromatin landscape to control virulence and secondary metabolism in a fungal pathogen

Xingmin Han
Chenghui Xu
Yiyi Ren
Meiling Guo
Jiayue Yan
Xuan Wang Chao Liu
... [+2 authors] ...,
Qin Gu
Xing-Xing Shen
Zhonghua Ma
Yun Chen

First Published October 14, 2025

Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data

Kaixuan Luo
Jianling Zhong
Alexias Safi
Linda K. Hong
Alok K. Tewari
Lingyun Song
... [+1 authors] ...,
Timothy E. Reddy
Li Ma
Gregory E. Crawford
Alexander J. Hartemink

First Published May 24, 2022

Correcting signal biases and detecting regulatory elements in STARR-seq data

Young-Sook Kim
Graham D. Johnson
Jungkyun Seo
Alejandro Barrera
Thomas N. Cowart
William H. Majoros
Alejandro Ochoa
Andrew S. Allen
Timothy E. Reddy

First Published March 15, 2021

AP-1 subunits converge promiscuously at enhancers to potentiate transcription

Jungkyun Seo
D. Dewran Koçak
Luke C. Bartelt
Courtney A. Williams
Alejandro Barrera
Charles A. Gersbach
Timothy E. Reddy

First Published March 5, 2021

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Ian C. McDowell
Alejandro Barrera
Anthony M. D'Ippolito
Christopher M. Vockley
Linda K. Hong
Sarah M. Leichter Luke C. Bartelt William H. Majoros Lingyun Song Alexias Safi D. Dewran Koçak Charles A. Gersbach
... [+7 authors] ...,
Alexander J. Hartemink
Gregory E. Crawford
Barbara E. Engelhardt
Timothy E. Reddy

First Published August 10, 2018

Genomic approaches for understanding the genetics of complex disease

William L. Lowe
Timothy E. Reddy

First Published October 1, 2015

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

Christopher M. Vockley
Cong Guo
William H. Majoros
Michael Nodzenski
Denise M. Scholtens
M. Geoffrey Hayes
William L. Lowe
Timothy E. Reddy

First Published June 17, 2015

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

Lauren R. Polstein
Pablo Perez-Pinera
D. Dewran Kocak
Christopher M. Vockley
Peggy Bledsoe
Lingyun Song
... [+1 authors] ...,
Alexias Safi
Gregory E. Crawford
Timothy E. Reddy
Charles A. Gersbach

First Published May 29, 2015

Dynamic DNA methylation across diverse human cell lines and tissues

Katherine E. Varley
Jason Gertz
Kevin M. Bowling
Stephanie L. Parker
Timothy E. Reddy
Florencia Pauli-Behn Marie K. Cross Brian A. Williams John A. Stamatoyannopoulos
... [+4 authors] ...,
Gregory E. Crawford
Devin M. Absher
Barbara J. Wold
Richard M. Myers

First Published January 16, 2013

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

Jason Gertz
Timothy E. Reddy
Katherine E. Varley
Michael J. Garabedian
Richard M. Myers

First Published September 26, 2012

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