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The impact of long-read sequencing on human population-scale genomics

  • First Published April 14, 2025
Perspective

Unraveling the hidden complexity of cancer through long-read sequencing

  • First Published March 20, 2025
Perspective

Notable challenges posed by long-read sequencing for the study of transcriptional diversity and genome annotation

  • First Published March 3, 2025
Perspective

Challenges in identifying mRNA transcript starts and ends from long-read sequencing data

  • First Published November 20, 2024
Perspective

Ribosome decision graphs for the representation of eukaryotic RNA translation complexity

  • First Published May 7, 2024
Perspective

Why community consultation matters in genomic research benefit-sharing models

  • First Published January 31, 2024
Perspective

Challenges and considerations for reproducibility of STARR-seq assays

  • First Published May 2, 2023
Perspective

Diversifying the genomic data science research community

  • First Published July 20, 2022
Perspective

Short arms of human acrocentric chromosomes and the completion of the human genome sequence

  • First Published March 31, 2022
Perspective

The genetics and epigenetics of satellite centromeres

  • First Published March 31, 2022
Perspective

Advances in spatial transcriptomic data analysis

  • First Published October 1, 2021
Perspective

Applications of single-cell genomics and computational strategies to study common disease and population-level variation

  • First Published October 1, 2021
Perspective

Cancer cell states and emergent properties of the dynamic tumor system

  • First Published October 1, 2021
Perspective

Tagmentation-based single-cell genomics

  • First Published October 1, 2021
Perspective

Decrypting noncoding RNA interactions, structures, and functional networks

  • First Published August 21, 2019
Perspective

Realizing the potential of blockchain technologies in genomics

  • First Published August 3, 2018
Perspective

Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship

  • First Published April 6, 2018
Perspective

Moving beyond Bermuda: sharing data to build a medical information commons

  • First Published April 3, 2017
Perspective

The path to routine use of genomic biomarkers in the cancer clinic

  • First Published October 1, 2015
Perspective

Defining cell types and states with single-cell genomics

  • First Published October 1, 2015
Perspective

The first five years of single-cell cancer genomics and beyond

  • First Published October 1, 2015
Perspective

The Mendelian disorders of the epigenetic machinery

  • First Published October 1, 2015
Perspective

Epigenomics and the structure of the living genome

  • First Published October 1, 2015
Perspective

Genomic approaches for understanding the genetics of complex disease

  • First Published October 1, 2015
Perspective

Enabling functional genomics with genome engineering

  • First Published October 1, 2015
Perspective

Biological data sciences in genome research

  • First Published October 1, 2015
Perspective

Linking RNA biology to lncRNAs

  • First Published October 1, 2015
Perspective

Parlez-vous VUS?

  • First Published October 1, 2015
Perspective

A vision for ubiquitous sequencing

  • First Published October 1, 2015
Perspective

Functional genomics bridges the gap between quantitative genetics and molecular biology

  • First Published October 1, 2015
Perspective

Can I be sued for that? Liability risk and the disclosure of clinically significant genetic research findings

  • First Published March 27, 2014
Perspective

Functional transcriptomics in the post-ENCODE era

  • First Published October 30, 2013
Perspective

From human genome to cancer genome: The first decade

  • First Published July 1, 2013
Perspective

Understanding the regulatory and transcriptional complexity of the genome through structure

  • First Published July 1, 2013
Perspective

Insights into neural crest development and evolution from genomic analysis

  • First Published July 1, 2013
Perspective

Comparative genomics as a tool to understand evolution and disease

  • First Published July 1, 2013
Perspective

Translating genomic information into clinical medicine: Lung cancer as a paradigm

  • First Published September 27, 2012
Perspective

Toward mapping the biology of the genome

  • First Published September 5, 2012
Perspective

What does our genome encode?

  • First Published September 5, 2012
Perspective

Human genomic disease variants: A neutral evolutionary explanation

  • First Published June 4, 2012
Perspective

Translating cancer ‘omics’ to improved outcomes

  • First Published February 1, 2012
Perspective

Translational genomics: The challenge of developing cancer biomarkers

  • First Published February 1, 2012
Perspective

Reading TE leaves: New approaches to the identification of transposable element insertions

  • First Published June 1, 2011
Perspective

Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

  • First Published February 4, 2011
Perspective

Transgenerational epigenetic inheritance: More questions than answers

  • First Published November 1, 2010
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