Microsatellite Marker Content Mapping of 12 Candidate Genes for Obesity: Assembly of Seven Obesity Screening Panels for Automated Genotyping

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Figure 1.
Figure 1.

STS content maps. The chromosome 4 subregion containing the NPY Y1R, NPY Y5R, and CPE genes is shown as an example of those generated in this study. The orientation of theCPE gene is indicated by a 3′ or 5′ following theCPE gene symbol and runs left to right. The orientation of the NPY Y5R and NPY Y1R genes could not be determined by the use of 3′ and 5′ primer sets relative to each other: YACs are shown as lines, the lengths of which reflect the number of included STSs and not actual size. Total size of individual YACs is listed next to the YAC name. The physical distances between adjacent STSs have not been determined directly. Inverted triangles indicate that the YAC was positive for the indicated STS: stars indicate that the YAC was positive for a particular candidate primer set; and diamonds indicate that the YAC was positive for a particular CPE primer set. Genetic distances (in cM) are indicated between selected STSs. Only YACs that were positive with more than one STS are shown. Asterisks above a STS name indicate a polymorphic marker with larger symbols denoting inclusion in a screening panel. Physical (STS content) maps for the following genes are available on the Genome Research web site http://www.genome.org: ART, APOJ,β-3AR, MC4R, NPY Y6R, PC 1, POMC, PPARγ, tub, andUCP2.

This Article

  1. Genome Res. 8: 985-994

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