Microsatellite Marker Content Mapping of 12 Candidate Genes for Obesity: Assembly of Seven Obesity Screening Panels for Automated Genotyping

Online Legend                                                                                 Winick & Friedman 18

STS content maps for the following candidate genes: the chromosome 16 subregion containing the ART gene; the chromosome 8 subregion containing the APOJ gene; the chromosome 8 subregion containing the b3AR gene; the chromosome 4 subregion containing the NPY Y1, NPY Y5 and CPE genes; the chromosome 18 subregion containing the MC4R gene the chromosome 5 subregion containing the NPY Y6 gene; the chromosome 5 subregion containing the PC1 gene; the chromosome 3 subregion containing the PPARg gene; ; the chromosome 11 subregion containing the tubby gene; the chromosome 11 subregion containing the UCP2 gene.  The orientation of the ART gene is indicated by a 3' or 5' following the ART gene symbol and runs left to right. The orientation of the CPE gene is indicated by a 3' or 5' following the CPE gene symbol and runs left to right. The orientation of the NPY Y6 gene is indicated by a 3' or 5' following the NPY Y6 gene symbol and runs left to right. The orientation of the PC1 gene is indicated by a 5' or 3’ following the PC1 gene symbol and runs left to right. The orientation of the following candidate genes could not be determined by the use of 3' & 5' primer sets relative to each other: APOJ, b3AR, NPY Y5, MC4R, PPARg, POMC, tubby and the UCP2 genes. YACs are shown as lines, the length of which reflects the number of included STSs and not actual size. Total size of individual YACs is listed next to the YAC name. The physical distances between adjacent STSs have not been determined directly. Inverted triangles indicate that the YAC was positive for the indicated STS. Stars indicate that the YAC was positive for a particular candidate primer set. Diamonds indicate that the YAC was positive for a particular CPE primer set. Genetic distances in cM are indicated between selected STSs.Only YACs that were found positive with more than one STS are shown. Asterisks above a STS name indicate a polymorphic marker with larger symbols denoting inclusion in a screening panel.


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  1. doi: 10.1101/gr.8.9.985 Genome Res. September 1, 1998 vol. 8 no. 9 985-994
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